Marburg virus - Revision history

Aidan: /* Prevent */

2020-08-28T13:41:50Z

Prevent

← Older revision		Revision as of 13:41, 28 August 2020
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	*Experimental therapies include [[favipiravir]] and monoclonal antibodies		*Experimental therapies include [[favipiravir]] and monoclonal antibodies

	==~~Prevent~~==		==Prevention==

	=== Vaccination ===		===Vaccination===

	*Vaccination is under investigation		*Vaccination is under investigation

	=== Infection Prevention and Control ===		===Infection Prevention and Control===

	* Isolate patient		*Isolate patient
	* Droplet precautions and face protection within 1 meter of patient		*Droplet precautions and face protection within 1 meter of patient
	* Limit hospital staff who have contact		*Limit hospital staff who have contact

	[[Category:Filoviridae]]		[[Category:Filoviridae]]

Aidan: /* Prevent */

2020-08-28T13:41:43Z

Prevent

← Older revision		Revision as of 13:41, 28 August 2020
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	*Mortality 23 to 90%		*Mortality 23 to 90%

	== Diagnosis ==		==Diagnosis==

	* RT-PCR at the National Microbiology Laboratory		*RT-PCR at the National Microbiology Laboratory
	** Inform microbiology lab beforehand and contact Public Health for collection instructions		**Inform microbiology lab beforehand and contact Public Health for collection instructions

	==Management==		==Management==
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	==Prevent==		==Prevent==

			=== Vaccination ===

	*Vaccination is under investigation		*Vaccination is under investigation

			=== Infection Prevention and Control ===

			* Isolate patient
			* Droplet precautions and face protection within 1 meter of patient
			* Limit hospital staff who have contact

	[[Category:Filoviridae]]		[[Category:Filoviridae]]

Aidan at 13:39, 28 August 2020

2020-08-28T13:39:32Z

← Older revision		Revision as of 13:39, 28 August 2020
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	==Background==		==Background==

	=== Microbiology ===		===Microbiology===

	*Negative-sense single-stranded RNA virus in the [[Filoviridae]] family		*Negative-sense single-stranded RNA virus in the [[Filoviridae]] family
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	**Ravn virus		**Ravn virus

	=== Epidemiology ===		===Epidemiology===

	* Rare, with 11 outbreaks since discovery in 1967, totalling 470 cases		*Rare, with 11 outbreaks since discovery in 1967, totalling 470 cases
	* Animal reservoir is [[Reservoir::fruit bat]], with a sylvian cycle that occasionally spills over into human populations		*Animal reservoir is [[Reservoir::fruit bat]], with a sylvian cycle that occasionally spills over into human populations
	** The range of the reservoir extends into Middle East, South Asia, and south Pacific, but the virus is essentially limited to subsaharan Africa		**The range of the reservoir extends into Middle East, South Asia, and south Pacific, but the virus is essentially limited to subsaharan Africa

	== Clinical Manifestations ==		==Clinical Manifestations==

	* Incubation period [[Usual incubation period::2 to 21 days]]		*Incubation period [[Usual incubation period::2 to 21 days]]
	* Starts with high fever, severe headache malaise		*Starts with high fever, severe headache malaise
	* Followed by multi-system involvement as early as day 3		*Followed by multi-system involvement as early as day 3
	** Nausea, vomiting, anorexia, abdominal pain, diarrhea (can persist for a week)		**Nausea, vomiting, anorexia, abdominal pain, diarrhea (can persist for a week)
	** Chest pain, dyspnea, cough		**Chest pain, dyspnea, cough
	** Hypotension, edema, maculopapular rash		**Hypotension, edema, maculopapular rash
	** Headache, confusion		**Headache, confusion
	* Mortality 23 to 90%		*Mortality 23 to 90%

	== ~~Management~~ ==		== Diagnosis ==

			* RT-PCR at the National Microbiology Laboratory
⚫	* Good supportive care decreases mortality substantially
			** Inform microbiology lab beforehand and contact Public Health for collection instructions
⚫	* Experimental therapies include [[favipiravir]] and monoclonal antibodies

	== ~~Prevent~~ ==		==Management==

		⚫	*Good supportive care decreases mortality substantially
⚫	* Vaccination is under investigation
		⚫	*Experimental therapies include [[favipiravir]] and monoclonal antibodies

			==Prevent==

		⚫	*Vaccination is under investigation

	[[Category:Filoviridae]]		[[Category:Filoviridae]]

Aidan at 13:38, 28 August 2020

2020-08-28T13:38:23Z

← Older revision		Revision as of 13:38, 28 August 2020
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	== ~~Microbiology~~ ==		==Background==

			=== Microbiology ===
⚫	* Negative-sense single-stranded RNA virus in the Filoviridae family

		⚫	*Negative-sense single-stranded RNA virus in the [[Filoviridae]] family
			*Genus contains two species
			**Marburg virus
			**Ravn virus

			=== Epidemiology ===

			* Rare, with 11 outbreaks since discovery in 1967, totalling 470 cases
			* Animal reservoir is [[Reservoir::fruit bat]], with a sylvian cycle that occasionally spills over into human populations
			** The range of the reservoir extends into Middle East, South Asia, and south Pacific, but the virus is essentially limited to subsaharan Africa

			== Clinical Manifestations ==

			* Incubation period [[Usual incubation period::2 to 21 days]]
			* Starts with high fever, severe headache malaise
			* Followed by multi-system involvement as early as day 3
			** Nausea, vomiting, anorexia, abdominal pain, diarrhea (can persist for a week)
			** Chest pain, dyspnea, cough
			** Hypotension, edema, maculopapular rash
			** Headache, confusion
			* Mortality 23 to 90%

			== Management ==

			* Good supportive care decreases mortality substantially
			* Experimental therapies include [[favipiravir]] and monoclonal antibodies

			== Prevent ==

			* Vaccination is under investigation

	[[Category:Filoviridae]]		[[Category:Filoviridae]]

Aidan: /* Microbiology */

2019-08-17T15:23:46Z

Microbiology

← Older revision		Revision as of 15:23, 17 August 2019
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	= Microbiology =		== Microbiology ==

	* Negative-sense single-stranded RNA virus in the Filoviridae family		* Negative-sense single-stranded RNA virus in the Filoviridae family

Aidan at 23:39, 14 August 2019

2019-08-14T23:39:45Z

← Older revision		Revision as of 23:39, 14 August 2019
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		⚫	= Microbiology =
	= Marburg virus (MARV) =

⚫	== Microbiology ==

	* Negative-sense single-stranded RNA virus in the Filoviridae family		* Negative-sense single-stranded RNA virus in the Filoviridae family

			[[Category:Filoviridae]]

Aidan: Aidan moved page RNA Marburg virus (MARV) to Marburg virus without leaving a redirect

2019-08-14T23:39:29Z

Aidan moved page RNA Marburg virus (MARV) to Marburg virus without leaving a redirect

← Older revision		Revision as of 23:39, 14 August 2019
(No difference)

Maintenance script: Imported from text file

2019-08-11T18:05:57Z

Imported from text file

New page

= Marburg virus (MARV) =

== Microbiology ==

* Negative-sense single-stranded RNA virus in the Filoviridae family