Aidan: /* Causes by risk factor */

2021-01-20T18:19:21Z

Causes by risk factor

← Older revision		Revision as of 18:19, 20 January 2021
Line 1:		Line 1:
	== Background ==		==Background==

	* Refers to enlargement of the lymph nodes		*Refers to enlargement of the lymph nodes

	==Differential Diagnosis==		==Differential Diagnosis==
Line 76:		Line 76:
	**'''Southeastern or central US:''' [[histoplasmosis]]		**'''Southeastern or central US:''' [[histoplasmosis]]
	**'''Southeast Asia, India, or northern Australia:''' [[scrub typhus]]		**'''Southeast Asia, India, or northern Australia:''' [[scrub typhus]]
	**'''Central or west Africa:''' African trypanosomiasis		**'''Central or west Africa:''' [[African trypanosomiasis]]
	**'''Central or South America:''' American trypanosomiasis		**'''Central or South America:''' [[American trypanosomiasis]]
	**'''East Africa, Mediterranean, China, or South/Central America:''' leishmaniasis		**'''East Africa, Mediterranean, China, or South/Central America:''' [[leishmaniasis]]
	**'''Mexico, Peru, Chile, India, Pakistan, Egypt, or Indonesia:''' typhoid fever		**'''Mexico, Peru, Chile, India, Pakistan, Egypt, or Indonesia:''' [[typhoid fever]]

	[[Category:Infectious diseases]]		[[Category:Infectious diseases]]

Aidan at 20:05, 17 November 2020

2020-11-17T20:05:22Z

← Older revision		Revision as of 20:05, 17 November 2020
Line 1:		Line 1:
			== Background ==

			* Refers to enlargement of the lymph nodes

	==Differential Diagnosis==		==Differential Diagnosis==

Aidan at 23:34, 15 November 2020

2020-11-15T23:34:34Z

Show changes

Maintenance script: Imported from text file

2020-07-04T01:17:43Z

Imported from text file

New page

== Differential Diagnosis ==

* Neoplasm
** Hematologic: lymphoma, leukemia
** Solid-tumour: squamous cell cancer of the head and neck
** Metastasis
* Infection
** Viral: HIV, EBV, HSV, CMV, mumps, measles, rubella, hepatitis B, dengue
** Bacterial
*** Regional: streptococcal pharyngitis, skin and soft tissue infections, tularemia, plague, cat scratch disease, diphtheria, chancroid, rat bite fever, Lyme disease
*** Generalized: brucellosis, leptospirosis, lymphogranuloma venereum, typhoid fever, secondary syphilis
** Mycobacterial: tuberculosis, non-tuberculous mycobacteria
** Fungal: histoplasmosis, coccidiomycosis, cryptococcosis
** Parasitic: toxoplasmosis, leishmaniasis
* Non-neoplastic lymphoproliferative disorders
** Angioimmunoblastic lymphadenopathy with dysproteinemia
** Autoimmune lymphoproliferative disease
** Rosai-Dorfman disease
** Hemophagocytic lymphohistiocytosis
* Immune-mediated
** Serum sickness
** Drug reactions: allopurinol, atenolol, captopril, carbamazepine, cephalosporins, ethosuximide, gold, hydralazine, imatinib, lamotrigine, penicillin, '''phenytoin''', primidone, pyrimethamine, quinidine, sulfonamides, sulindac
** IgG4-related disease
* Endocrine and metabolism
** Addison disease
** Lipid storage disease
* Other
** Sarcoidosis
** Multicentric Castleman disease
** Amyloidosis
** Histiocytosis
** Chronic granulomatous disease
** Kikuchi disease
** Kawasaki disease
** Inflammatory pseudotumor
** Systemic lupus erythematosus
** Rheumatoid arthritis
** Still disease
** Dermatomyositis
** Eosinophilic granulomatosis with polyangiitis

=== Causes by location ===

* '''Cervical:''' EBV, CMV, toxoplasmosis, tuberculosis or non-tuberculous mycobacteria (if more chronic with less tenderness), cat scratch disease, metastatic head-and-neck cancer
* '''Preauricular:''' conjunctivitis, Parinaud oculoglandular syndrome (cat scratch disease)
* '''Postauricular:''' parietotemporal scalp infection, rubella
* '''Suboccipital:''' posterior scalp infection
* '''Supraclavicular:''' malignancy (especially intraabdominal malignancy)
* '''Axillary:''' infections of the arm (including cat scratch disease), malignancy (including breast and metastasis), foreign body reaction to silicone breast implants
* '''Epitrochlear:''' infections of the forearm or hand, lymphoma, sarcoidosis, tularemia, and secondary syphilis
* '''Inguinal:''' trauma, lower limb infections, STIs (chancroid, LGV, herpes, syphilis), malignancy (including skin on legs, cervix, vulva, skin on trunk, rectum/anus, ovary, penis)
* '''Generalized:'''
** '''More common:''' HIV, tuberculosis, mononucleosis, lupus, medications, sarcoidosis, lymphoma
** '''Less common:''' Castleman disease,Kikuchi disease, Kawasaki disease, angioimmunoblastic T-cell lymphoma, inflammatory pseudotumour, amyloidosis, Kimura disease, progressive transformation of germinal centres, Fosai-Dorfman disease, IgG4-related disease

=== Causes by risk factor ===

* '''Animal exposure'''

* '''Cat:''' cat-scratch disease, toxoplasmosis
** '''Undercooked meat:''' toxoplasmosis
** '''Tick bite:''' Lyme disease, tularemia
** '''Tuberculosis:''' tuberculous adenitis
** '''Transfusion or transplant:''' CMV, HIV
** '''High-risk sexual behaviour:''' HIV, syphilis, HSV, CMV, hepatitis B
** '''Intravenous drug use:''' HIV, endocarditis, hepatitis B

* '''Occupational'''
* '''Hunters and trappers:''' tularemia
** '''Fishermen and butchers:''' erysipeloid
* '''Travel-related'''
* '''Arizona, southern California, New Mexico, and western Texas:''' coccidiomycosis
** '''Southwestern US:''' plague
** '''Southeastern or central US:''' histoplasmosis
** '''Southeast Asia, India, or northern Australia:''' scrub typhus
** '''Central or west Africa:''' African trypanosomiasis
** '''Central or South America:''' American trypanosomiasis
** '''East Africa, Mediterranean, China, or South/Central America:''' leishmaniasis
** '''Mexico, Peru, Chile, India, Pakistan, Egypt, or Indonesia:''' typhoid fever

[[Category:Infectious diseases]]
[[Category:Hematology]]
[[Category:Clinical exam]]

Lymphadenopathy - Revision history

Aidan: /* Causes by risk factor */

Aidan at 20:05, 17 November 2020

Aidan at 23:34, 15 November 2020

Maintenance script: Imported from text file