https://idwiki.org/index.php?action=history&feed=atom&title=Leukocytoclastic_vasculitis 2026-04-29T02:07:40Z Revision history for this page on the wiki MediaWiki 1.43.8 https://idwiki.org/index.php?title=Leukocytoclastic_vasculitis&diff=8176&oldid=prev 2021-11-11T22:30:14Z

<p>Created page with &quot;== Background == * Histopathologic description of a small-vessel <a href="/Vasculitis" title="Vasculitis">vasculitis</a>, typically of the skin * Includes <a href="/index.php?title=Cutaneous_leukocytoclastic_angiitis&amp;action=edit&amp;redlink=1" class="new" title="Cutaneous leukocytoclastic angiitis (page does not exist)">cutaneous leukocytoclastic angiitis</a> and cutaneous arte...&quot;</p> <p><b>New page</b></p><div>== Background ==<br /> <br /> * Histopathologic description of a small-vessel [[vasculitis]], typically of the skin<br /> * Includes [[cutaneous leukocytoclastic angiitis]] and [[cutaneous arteritis]]<br /> <br /> == Etiology ==<br /> <br /> * Idiopathic in 50%<br /> * Infections<br /> ** Post-infectious sequela of [[streptococcal pharyngitis]]<br /> ** [[Mycobacterium]], [[Staphylococcus aureus]], [[Chlamydia]], [[Neisseria meningitidis|Neisseria]], and [[HIV]]<br /> ** Chronic [[hepatitis B]], [[hepatitis C]], and [[syphilis]]<br /> * Drugs, typically with onset 1 to 3 weeks after starting<br /> ** Antibiotics: beta lactams, [[erythromycin]], [[clindamycin]], [[vancomycin]], sulfonamides<br /> ** Others: [[furosemide]], [[allopurinol]], NSAIDs, [[amiodarone]], [[gold]], thiazides, [[phenytoin]], beta blockers, TNF-alpha inhibitors, SSRIs, [[metformin]], [[warfarin]], [[valproic acid]]<br /> * Neoplastic: [[lymphoma]], [[leukemia]], colorectal adenocarcinoma, [[lung cancer]]<br /> * Autoimmune diseases<br /> ** [[Systemic lupus erythematosus]]<br /> ** [[Sjogren syndrome]]<br /> ** [[IBD]]<br /> ** Behcet disease<br /> ** [[Rheumatoid arthritis]]<br /> ** [[Cryoglobulinemic vasculitis]]<br /> ** [[IgA vasculitis]]<br /> ** [[Hypocomplementemic urticarial vasculitis]]<br /> ** [[Erythema elevatum diutinum]]<br /> <br /> == Investigations ==<br /> <br /> * Biopsy<br /> * If systemic involvement, get ANA, ENA, ANCA, C3/C4, RF, cryoglobulins, SPEP, aPTT, hepatitis B, hepatitis C, and HIV<br /> * Second-line investigations include cryofibrinogen, lupus anticoagulant, anti-B2-glycoprotein, anti-cardiolipin, and-dsDNA, anti-CCP, serum IgA levels, celiac testing, cold agglutinins, echocardiography, blood and urine cultures<br /> <br /> [[Category:Rheumatology]]</div>

Aidan