Legionella - Revision history

Aidan at 15:54, 13 February 2025

2025-02-13T15:54:38Z

← Older revision		Revision as of 15:54, 13 February 2025
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	*Presents as a community-acquired or healthcare-associated pneumonia		*Presents as a community-acquired or healthcare-associated pneumonia
	*May have a prodrome of hours to days that involves ~~headaches~~, myalgias, asthenia, and anorexia, possibly fevers		*May have a prodrome of hours to days that involves [[Causes::headache\|headache]], myalgias, [[Causes::asthenia\|asthenia]], and anorexia, possibly fevers
	**Diarrhea and abdominal pain		**[[Causes::Diarrhea\|Diarrhea]] and abdominal pain
	**Cough, sometimes chest pain, sometimes productive		**Cough, sometimes chest pain, sometimes productive
	*Fevers with pulse-temperature dissociation, myalgias, nonproductive cough, diarrhea, confusion, hyponatremia, hypophosphatemia, and elevated liver enzymes		*Fevers with [[Causes::pulse-temperature dissociation\|pulse-temperature dissociation]], myalgias, nonproductive cough, diarrhea, confusion, hyponatremia, hypophosphatemia, and elevated liver enzymes
	*Can have leukopenia, thrombocytopenia, DIC, leukocytosis, pyuria		*Can have leukopenia, thrombocytopenia, DIC, leukocytosis, pyuria

2023-12-12T15:19:24Z

← Older revision		Revision as of 15:19, 12 December 2023
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	\|60-95%		\|60-95%
	\|>99%		\|>99%
	\|Highest sensitivity for serogroup 1, Pontiac type; positive for days to months		\|Highest sensitivity for serogroup 1, Pontiac type; positive for days to months, even up to a year
	\|-		\|-
	\|Immunofluorescent microscopy		\|Immunofluorescent microscopy
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	==Management==		==Management==

	*~~First-line~~: [[Is treated by::Levofloxacin]] 750 mg PO or IV once daily or [[Is treated by::moxifloxacin]] 400 mg PO or IV once daily		*Treatments include: [[Is treated by::Levofloxacin]] 750 mg PO or IV once daily, [[Is treated by::moxifloxacin]] 400 mg PO or IV once daily, or [[Is treated by::azithromycin]] 500 mg PO or IV once daily
	*Alternative: [[Is treated by::~~azithromycin~~]] ~~500~~ mg ~~PO or IV~~ ~~once~~ daily		*Alternative is [[Is treated by::doxycycline]] 100 mg p.o. twice daily
	*Usual duration 7-10 days		*Usual duration 7-10 days
	*No need to treat Pontiac fever		*No need to treat Pontiac fever

2023-04-12T15:58:36Z

Microbiology

← Older revision		Revision as of 15:58, 12 April 2023
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	**Requires media enriched with L-cysteine		**Requires media enriched with L-cysteine
	*''L. pneumophila'' is an facultative intracellular parasite of a number of amoebae		*''L. pneumophila'' is an facultative intracellular parasite of a number of amoebae
	*Close relative of ''[[Coxiella ~~burnetti~~]]''		*Close relative of [[Coxiella burnetii]]
	*Also have a quiescent state that is "viable but not cultivable"		*Also have a quiescent state that is "viable but not cultivable"

2022-08-27T13:51:21Z

moved and fixed display title

← Older revision		Revision as of 13:51, 27 August 2022
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	*https://www.cdc.gov/legionella/health-depts/index.html		*https://www.cdc.gov/legionella/health-depts/index.html

	{{DISPLAYTITLE:''Legionella''		{{DISPLAYTITLE:''Legionella''}}
	[[Category:Gram-negative bacilli]]		[[Category:Gram-negative bacilli]]

2022-08-27T13:51:02Z

Aidan moved page Legionella species to Legionella without leaving a redirect

← Older revision	Revision as of 13:51, 27 August 2022
(No difference)

2022-02-08T02:53:56Z

Text replacement - " species}}" to ""

← Older revision		Revision as of 02:53, 8 February 2022
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	*https://www.cdc.gov/legionella/health-depts/index.html		*https://www.cdc.gov/legionella/health-depts/index.html

	{{DISPLAYTITLE:''Legionella'' ~~species}}~~		{{DISPLAYTITLE:''Legionella''
	[[Category:Gram-negative bacilli]]		[[Category:Gram-negative bacilli]]

2020-10-15T02:43:57Z

Text replacement - "[[Cellular shape::" to "[[Shape::"

← Older revision		Revision as of 02:43, 15 October 2020
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	===Microbiology===		===Microbiology===

	*Small, fastidious [[Stain::Gram-negative]] [[~~Cellular shape~~::bacillus]]		*Small, fastidious [[Stain::Gram-negative]] [[Shape::bacillus]]
	*Uses proteins rather than carbohydrates as an energy source		*Uses proteins rather than carbohydrates as an energy source
	**Requires media enriched with L-cysteine		**Requires media enriched with L-cysteine

2020-08-27T11:34:05Z

Clinical Manifestations

← Older revision		Revision as of 11:34, 27 August 2020
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	*Incubation period of [[Usual incubation period::2 to 10 days]] (median 4 to 6 days); at most [[Incubation period range::up to 28 days]]		*Incubation period of [[Usual incubation period::2 to 10 days]] (median 4 to 6 days); at most [[Incubation period range::up to 28 days]]

	===Legionnaires' ~~disease~~===		===Legionnaires' Disease===

	*Presents as a community-acquired or healthcare-associated pneumonia		*Presents as a community-acquired or healthcare-associated pneumonia
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	*Can have leukopenia, thrombocytopenia, DIC, leukocytosis, pyuria		*Can have leukopenia, thrombocytopenia, DIC, leukocytosis, pyuria

	===Extrapulmonary ~~infections~~===		===Extrapulmonary Infections===

	*Rare, in immunocompromised patients or severe illness		*Rare, in immunocompromised patients or severe illness
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	*Case reports of endocarditis		*Case reports of endocarditis

	===Pontiac ~~fever~~===		===Pontiac Fever===

	*Incubation period 4 hours to 3 days		*Incubation period 4 hours to 3 days

2020-08-05T14:13:35Z

Clinical Manifestations

← Older revision		Revision as of 14:13, 5 August 2020
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	==Clinical Manifestations==		==Clinical Manifestations==

	*Incubation period of [[Usual incubation period::2 to 10 days]] (median 4 to 6 days); [[Incubation period range::at ~~most~~ 28 days]]		*Incubation period of [[Usual incubation period::2 to 10 days]] (median 4 to 6 days); at most [[Incubation period range::up to 28 days]]

	===Legionnaires' disease===		===Legionnaires' disease===

2020-08-05T13:51:16Z

Clinical Manifestations

← Older revision		Revision as of 13:51, 5 August 2020
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	==Clinical Manifestations==		==Clinical Manifestations==

	*Incubation period of 2 to 10 days (median 4 to 6 days); at most 28 days		*Incubation period of [[Usual incubation period::2 to 10 days]] (median 4 to 6 days); [[Incubation period range::at most 28 days]]

	===Legionnaires' disease===		===Legionnaires' disease===