Lead toxicity - Revision history

Aidan: /* Investigations */

2020-10-23T14:12:21Z

Investigations

← Older revision		Revision as of 14:12, 23 October 2020
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	== Background ==		==Background==

	=== Pathophysiology ===		===Pathophysiology===

	* Lead has multisystem effects, and is a powerful neurotoxin		*Lead has multisystem effects, and is a powerful neurotoxin

	===Risk Factors===		===Risk Factors===
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	**[[Miscarriage]] and [[stillbirth]]		**[[Miscarriage]] and [[stillbirth]]

	== Investigations ==		==Investigations==

	*Labs:		*Labs:
	**CBC showing [[microcytic anemia]]		**CBC showing [[microcytic anemia]]
	**Peripheral blood film showing basophilic stippling		**Peripheral blood film showing basophilic stippling

			== Diagnosis ==

			* Blood lead level strongly correlates with exposure level and health effects
			** Shows acute exposures (i.e. within months)
			* Since lead deposits in the bones, can do X-ray defraction for cumulative lead exposure

	[[Category:Toxicology]]		[[Category:Toxicology]]

Aidan at 13:44, 23 October 2020

2020-10-23T13:44:49Z

← Older revision		Revision as of 13:44, 23 October 2020
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	== ~~Risk Factors~~ ==		== Background ==

			=== Pathophysiology ===
⚫	* Occupational exposure to lead
⚫	** Battery manufacturing
⚫	** Plumbing
⚫	** Mining
⚫	** Painting
⚫	** Paper hanging
⚫	** Auto repair

			* Lead has multisystem effects, and is a powerful neurotoxin
⚫	== Clinical Manifestations ==

			===Risk Factors===
⚫	* Acute exposure

⚫	** Abdominal pain and constipation
		⚫	*Occupational exposure to lead:
⚫	** Headache, cognitive deficits, and peripheral neuropathy
		⚫	**Battery manufacturing
⚫	** Myalgias and arthralgias
		⚫	**Plumbing
⚫	** Anemia
		⚫	**Mining
⚫	** Anorexia
		⚫	**Painting
⚫	* Chronic exposure
		⚫	**Paper hanging
⚫	** Fatigue and insomnia
		⚫	**Auto repair
⚫	** Hypertension

⚫	** Neuropsychiatric symptoms
		⚫	==Clinical Manifestations==
⚫	** Nephropathy

	** Miscarriages and stillbirths Investigations
		⚫	*Acute exposure
⚫	* Labs:
		⚫	**[[Abdominal pain]] and [[constipation]]
⚫	** CBC showing microcytic anemia
		⚫	**[[Headache]], cognitive deficits, and [[peripheral neuropathy]]
⚫	** Peripheral blood film showing basophilic stippling
		⚫	**Myalgias and arthralgias
		⚫	**[[Anemia]]
		⚫	**Anorexia
		⚫	*Chronic exposure
		⚫	**Fatigue and [[insomnia]]
		⚫	**[[Hypertension]]
		⚫	**Neuropsychiatric symptoms
		⚫	**[[Nephropathy]]
			**[[Miscarriage]] and [[stillbirth]]

			== Investigations ==

		⚫	*Labs:
		⚫	**CBC showing [[microcytic anemia]]
		⚫	**Peripheral blood film showing basophilic stippling

	[[Category:Toxicology]]		[[Category:Toxicology]]

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-14T23:53:53Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 23:53, 14 July 2020
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	** Auto repair		** Auto repair

	== Clinical ~~Presentation~~ ==		== Clinical Manifestations ==

	* Acute exposure		* Acute exposure

Maintenance script: Imported from text file

2020-07-04T01:17:42Z

Imported from text file

New page

== Risk Factors ==

* Occupational exposure to lead
** Battery manufacturing
** Plumbing
** Mining
** Painting
** Paper hanging
** Auto repair

== Clinical Presentation ==

* Acute exposure
** Abdominal pain and constipation
** Headache, cognitive deficits, and peripheral neuropathy
** Myalgias and arthralgias
** Anemia
** Anorexia
* Chronic exposure
** Fatigue and insomnia
** Hypertension
** Neuropsychiatric symptoms
** Nephropathy
** Miscarriages and stillbirths Investigations
* Labs:
** CBC showing microcytic anemia
** Peripheral blood film showing basophilic stippling

[[Category:Toxicology]]