Kaposi sarcoma-associated herpesvirus - Revision history

Aidan: /* Clinical Manifestations */

2023-10-26T13:39:54Z

Clinical Manifestations

← Older revision		Revision as of 13:39, 26 October 2023
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	** Causes effusions isolated to the pleural, pericardial, or abdominal cavities		** Causes effusions isolated to the pleural, pericardial, or abdominal cavities
	** Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI tract		** Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI tract
	* Multicentric Castleman disease (MCD)		* [[Multicentric Castleman disease]] (MCD)
	** Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly		** Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly
	* Kaposi sarcoma-associated herpesvirus inflammatory cytokine syndrome (KICS)		* Kaposi sarcoma-associated herpesvirus inflammatory cytokine syndrome (KICS)

Aidan: Aidan moved page Kaposi sarcoma–associated herpesvirus to Kaposi sarcoma-associated herpesvirus without leaving a redirect

2022-11-11T11:42:48Z

Aidan moved page Kaposi sarcoma–associated herpesvirus to Kaposi sarcoma-associated herpesvirus without leaving a redirect

← Older revision		Revision as of 11:42, 11 November 2022
(No difference)

Aidan at 12:58, 2 October 2022

2022-10-02T12:58:37Z

← Older revision		Revision as of 12:58, 2 October 2022
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	== Background ==		== Background ==
			* One of the [[human herpesviruses]] (family [[Family::Herpesviridae]], subfamily [[Subfamily::Gammaherpesvirinae\|''Gammaherpesvirinae'']])
	* Seroprevalence varies by geography and group		* Seroprevalence varies by geography and group
	** US general population 1-5%		** US general population 1-5%

Aidan: Aidan moved page Human herpesvirus 8 to Kaposi sarcoma–associated herpesvirus

2022-10-02T12:56:35Z

Aidan moved page Human herpesvirus 8 to Kaposi sarcoma–associated herpesvirus

← Older revision		Revision as of 12:56, 2 October 2022
(No difference)

Aidan at 12:55, 2 October 2022

2022-10-02T12:55:24Z

← Older revision		Revision as of 12:55, 2 October 2022
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	* For [[Kaposi sarcoma]] with symptomatic visceral involvement, chemotherapy is recommended		* For [[Kaposi sarcoma]] with symptomatic visceral involvement, chemotherapy is recommended
	** May be indicated for disseminated cutaneous KS as well		** May be indicated for disseminated cutaneous KS as well

			== Further Reading ==

			* Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV. NIH, CDC, HIVMA, and IDSA. Available at https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-opportunistic-infection

	[[Category:Human herpesviruses]]		[[Category:Human herpesviruses]]

Aidan at 12:21, 2 October 2022

2022-10-02T12:21:45Z

← Older revision		Revision as of 12:21, 2 October 2022
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	== Background ==		== Background ==
	* Seroprevalence ~~variés~~ by geography and group		* Seroprevalence varies by geography and group
	** US general population 1-5%		** US general population 1-5%
	** US men who have sex with men 15-20%		** US men who have sex with men 15-20%
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	** Some Mediterranean countries 10-20%		** Some Mediterranean countries 10-20%
	** Sub-Saharan African countries 30-80%		** Sub-Saharan African countries 30-80%
			* Possibly transmitted through saliva or sex

	== Clinical Manifestations ==		== Clinical Manifestations ==
	* Mostly asymptomatic		* Mostly asymptomatic
			* Primary infection consists of fever, rash, lymphadenopathy, and bone marrow failure, and may rapidly progress to [[Kaposi sarcoma]]
	* [[Kaposi sarcoma]]		* [[Kaposi sarcoma]] (KS)
			** Hyperpigmented macules or nodules
			** Mostly skin but can include mouth, respiratory tract, and GI tract as well
	* Primary effusion lymphoma (PEL)		* Primary effusion lymphoma (PEL)
	** Causes effusions isolated ~~within~~ the pleural, pericardial, or abdominal cavities		** Causes effusions isolated to the pleural, pericardial, or abdominal cavities
	** Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI		** Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI tract
	* Multicentric Castleman disease (MCD)		* Multicentric Castleman disease (MCD)
	** Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly		** Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly
			* Kaposi sarcoma-associated herpesvirus inflammatory cytokine syndrome (KICS)
			** Like MCD but without pathology demonstrating MCD
			** Patients are often critically ill

	== Management ==		== Management ==
	* ~~See~~ [[Kaposi sarcoma]]		* For [[Kaposi sarcoma]] with symptomatic visceral involvement, chemotherapy is recommended
			** May be indicated for disseminated cutaneous KS as well

	[[Category:Human herpesviruses]]		[[Category:Human herpesviruses]]

Aidan: added a few other clinical manifestations

2022-10-01T18:14:26Z

added a few other clinical manifestations

← Older revision		Revision as of 18:14, 1 October 2022
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	* Mostly asymptomatic		* Mostly asymptomatic
	* [[Kaposi sarcoma]]		* [[Kaposi sarcoma]]
			* Primary effusion lymphoma (PEL)
			** Causes effusions isolated within the pleural, pericardial, or abdominal cavities
			** Occasionally causes mass lesions and extracavitary disease within skin, hematopoietic organs, and the GI
			* Multicentric Castleman disease (MCD)
			** Causes systemic symptoms including fever and night sweats, generalized adenopathy, fever, and hepatosplenomegaly

	== Management ==		== Management ==

Aidan: Created page with "== Background == * Seroprevalence variés by geography and group US general population 1-5% US men who have sex with men 15-20% US MSM with HIV 30-35% Some Mediterranean countries 10-20% ** Sub-Saharan African countries 30-80% == Clinical Manifestations == * Mostly asymptomatic * Kaposi sarcoma == Management == * See Kaposi sarcoma Category:Human herpesviruses"

2022-10-01T17:57:13Z

Created page with "== Background == * Seroprevalence variés by geography and group ** US general population 1-5% ** US men who have sex with men 15-20% ** US MSM with HIV 30-35% ** Some Mediterranean countries 10-20% ** Sub-Saharan African countries 30-80% == Clinical Manifestations == * Mostly asymptomatic * Kaposi sarcoma == Management == * See Kaposi sarcoma Category:Human herpesviruses"

New page

== Background ==
* Seroprevalence variés by geography and group
** US general population 1-5%
** US men who have sex with men 15-20%
** US MSM with HIV 30-35%
** Some Mediterranean countries 10-20%
** Sub-Saharan African countries 30-80%

== Clinical Manifestations ==
* Mostly asymptomatic
* [[Kaposi sarcoma]]

== Management ==
* See [[Kaposi sarcoma]]

[[Category:Human herpesviruses]]