Japanese encephalitis virus - Revision history

Aidan at 15:18, 13 March 2023

2023-03-13T15:18:00Z

← Older revision		Revision as of 15:18, 13 March 2023
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	== Background ==		== Background ==

			=== Virology ===
	* Single-stranded positive-sense enveloped virus in the family [[Flaviviridae]] and genus [[Flavivirus]]		* Single-stranded positive-sense enveloped virus in the family [[Flaviviridae]] and genus [[Flavivirus]]

	* Found in Asian and the western Pacific
			=== Epidemiology ===
	* Reservoir is pig and wading birds
	* Vector-borne, transmitted by [[Vector::Culex]] mosquitoes		* Vector-borne, transmitted by [[Vector::Culex]] mosquitoes, mainly [[Vector::Culex tritaeniorhynchus]]
			* Found in Asia and the western Pacific, including India, southeast Asia, and eastern Asia, and as far south as parts of northern Australia
			* Enzoonotic transmission cycle includes mosquitoes, pigs, and water birds, primarily in rural and periurban areas
			* Seasonal transmission
			** In temperate climates, transmission is more common in the warm season, which can include outbreaks and epidemics
			** In tropical and subtropical climates, transmission is year-round, but intensifies during the rainy season and in the pre-harvest season where rice is grown
	* More common in children and non-immune adults		* More common in children and non-immune adults
	* Overall, extremely low risk for travellers with 66 cases in Western travellers since 1973 and estimated less than 1 case per 10 million trips		* Overall, extremely low risk for travellers with 66 cases in Western travellers since 1973 and estimated less than 1 case per 10 million trips
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	* Incubation period of [[Usual incubation period::5 to 15 days]]		* Incubation period of [[Usual incubation period::5 to 15 days]]
	* 99% of infections are asymptomatic		* 99% of infections are asymptomatic
			* Mild infections can cause fever and headache, with or without other symptoms
⚫	* ~~Syndrome~~ ~~is characterized by~~ [[parkinsonism]]
			* Severe illness has rapid onset high fever, headache, neck stiffness, disorientation, coma, seizures, spastic paralysis, and death
		⚫	** May have [[parkinsonism]]

	=== Prognosis and Complications ===		=== Prognosis and Complications ===

	* 20-30% mortality among people who develop encephalitis		* 20-30% mortality among people who develop encephalitis
	* 30-50% of survivors have neuropsychiatric symptoms		* 30-50% of survivors have permanent neuropsychiatric symptoms, including paralysis, seizures, and aphasia

	== Management ==		== Management ==

Aidan: Text replacement - " species]]" to "]]"

2022-01-26T19:58:21Z

Text replacement - " species]]" to "]]"

← Older revision		Revision as of 19:58, 26 January 2022
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	* Found in Asian and the western Pacific		* Found in Asian and the western Pacific
	* Reservoir is pig and wading birds		* Reservoir is pig and wading birds
	* Vector-borne, transmitted by [[Vector::Culex ~~species~~]] mosquitoes		* Vector-borne, transmitted by [[Vector::Culex]] mosquitoes
	* More common in children and non-immune adults		* More common in children and non-immune adults
	* Overall, extremely low risk for travellers with 66 cases in Western travellers since 1973 and estimated less than 1 case per 10 million trips		* Overall, extremely low risk for travellers with 66 cases in Western travellers since 1973 and estimated less than 1 case per 10 million trips

Aidan: Created page with "== Background == * Single-stranded positive-sense enveloped virus in the family Flaviviridae and genus Flavivirus * Found in Asian and the western Pacific * Reservoir..."

2020-08-18T11:00:23Z

Created page with "== Background == * Single-stranded positive-sense enveloped virus in the family Flaviviridae and genus Flavivirus * Found in Asian and the western Pacific * Reservoir..."

New page

== Background ==

* Single-stranded positive-sense enveloped virus in the family [[Flaviviridae]] and genus [[Flavivirus]]
* Found in Asian and the western Pacific
* Reservoir is pig and wading birds
* Vector-borne, transmitted by [[Vector::Culex species]] mosquitoes
* More common in children and non-immune adults
* Overall, extremely low risk for travellers with 66 cases in Western travellers since 1973 and estimated less than 1 case per 10 million trips

== Clinical Manifestations ==

* Incubation period of [[Usual incubation period::5 to 15 days]]
* 99% of infections are asymptomatic
* Syndrome is characterized by [[parkinsonism]]

=== Prognosis and Complications ===

* 20-30% mortality among people who develop encephalitis
* 30-50% of survivors have neuropsychiatric symptoms

== Management ==

* Supportive

== Prevention ==

* Vaccine is not routinely recommended due to the rarity of disease
* Vaccine may be considered if there will be rural exposure, repeated travel to risk areas, longer cumulative duration of travel (e.g., > 30 days), or travel in areas suffering an outbreak
** However, disease is still rare

[[Category:Infectious diseases]]
[[Category:Vector-borne infections]]
[[Category:CNS infections]]