Isavuconazole - Revision history

Aidan at 17:31, 9 February 2026

2026-02-09T17:31:49Z

← Older revision		Revision as of 17:31, 9 February 2026
Line 59:		Line 59:
	==Dosing==		==Dosing==

	*~~Isavuconazole~~ 200 mg IV ~~tid~~ for 6 doses followed by 200 mg IV daily		*[[Invasive aspergillosis]]: 200 mg p.o./IV three times daily for 6 doses followed by 200 mg p.o./IV daily
			*[[Coccidioiomycosis]]: 200 mg p.o./IV q8h for 6 doses, followed by 200 mg p.o./IV every 24 hours

	=== Renal Dosing ===		=== Renal Dosing ===

2024-10-22T13:27:48Z

@@ Line 19: / Line 19: @@
 !ATU
 !R
 |-
 |[[Aspergillus flavus]]
@@ Line 90: / Line 48: @@
 |≤1
 |—
-|>2
+|>1
 |}
 ==Dosing==

2024-10-22T13:08:03Z

updated aspergillus to EUCAST 2020

2024-10-22T13:03:20Z

← Older revision		Revision as of 13:03, 22 October 2024
Line 10:		Line 10:
	*Indications include {{#ask: [[Is treated by::isavuconazole]]}}		*Indications include {{#ask: [[Is treated by::isavuconazole]]}}

			=== Breakpoints ===
			{\| class="wikitable"
			! rowspan="2" \|Species
			! rowspan="2" \|ECOFF (mg/L)
			! colspan="4" \|Breakpoints (μg/mL)
			! colspan="4" \|Breakpoints (mm)
			\|-
			! S
			!I
			!SDD
			!R
			!S
			! I
			!SDD
			!R
			\|-
			\|[[Candida albicans]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Candida glabrata]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Candida krusei]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Candida parapsilosis]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Candida tropicalis]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Cryptococcus neoformans]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Cryptococcus gattii]]
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|
			\|-
			\|[[Aspergillus flavus]]
			\|2
			\|—
			\| colspan="2" rowspan="5" \|
			\|—
			\| colspan="4" rowspan="5" \|
			\|-
			\|[[Aspergillus fumigatus]]
			\|2
			\|≤1
			\|>1
			\|-
			\|[[Aspergillus nidulans]]
			\|0.25
			\|≤0.25
			\|>0.25
			\|-
			\|[[Aspergillus niger]]
			\|4
			\|—
			\|—
			\|-
			\|[[Aspergillus terreus]]
			\|1
			\|≤1
			\|>1
			\|}
	==Dosing==		==Dosing==

2022-03-30T13:23:47Z

Safety

← Older revision		Revision as of 13:23, 30 March 2022
Line 28:		Line 28:
	* Nausea, vomiting, diarrhea		* Nausea, vomiting, diarrhea
	* Elevated liver enzymes		* Elevated liver enzymes
			**Generally transient ALT elevation that does not require change in therapy
			**May also include severe cholestatic or hepatocellular enzyme rises within the first few months of therapy
			**See also [https://www.ncbi.nlm.nih.gov/books/NBK548643/ LiverTox]
	* Hypokalemia		* Hypokalemia

2022-01-27T20:52:09Z

Text replacement - " species]]" to "]]"

← Older revision		Revision as of 20:52, 27 January 2022
Line 7:		Line 7:
	=== Spectrum of Activity ===		=== Spectrum of Activity ===

	*Active against [[Candida]], [[Cryptococcus]], [[Aspergillus ~~species~~]] including [[Aspergillus flavus]], [[Aspergillus fumigatus]], and [[Aspergillus niger]], and [[Mucorales]]		*Active against [[Candida]], [[Cryptococcus]], [[Aspergillus]] including [[Aspergillus flavus]], [[Aspergillus fumigatus]], and [[Aspergillus niger]], and [[Mucorales]]
	*Indications include {{#ask: [[Is treated by::isavuconazole]]}}		*Indications include {{#ask: [[Is treated by::isavuconazole]]}}

2020-09-03T10:59:40Z

@@ Line 1: / Line 1: @@
 *Indications include {{#ask: [[Is treated by::isavuconazole]]}}
@@ Line 4: / Line 13: @@
 *Isavuconazole 200 mg IV tid for 6 doses followed by 200 mg IV daily
 [[Category:Triazoles]]

2020-08-26T11:02:54Z

← Older revision		Revision as of 11:02, 26 August 2020
Line 1:		Line 1:
			*Indications include {{#ask: [[Is treated by::isavuconazole]]}}
⚫	== Dosing ==

		⚫	==Dosing==
⚫	* Isavuconazole 200 mg IV tid for 6 doses followed by 200 mg IV daily

		⚫	*Isavuconazole 200 mg IV tid for 6 doses followed by 200 mg IV daily

	[[Category:Triazoles]]		[[Category:Triazoles]]

2020-08-26T11:01:08Z

Created page with "== Dosing == * Isavuconazole 200 mg IV tid for 6 doses followed by 200 mg IV daily Category:Triazoles"

New page

== Dosing ==

* Isavuconazole 200 mg IV tid for 6 doses followed by 200 mg IV daily

[[Category:Triazoles]]