Invasive fungal sinusitis - Revision history

Aidan: /* Microbiology */

2020-08-16T00:32:27Z

Microbiology

← Older revision		Revision as of 00:32, 16 August 2020
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	== Background ==		==Background==

	===Microbiology===		===Microbiology===

			*[[Aspergillus]]
	*[[Zygomycetes]]: [[Mucor]], [[Rhizopus]]		*[[Zygomycetes]]: [[Mucor]], [[Rhizopus]]
	*[[Fusarium]]		*[[Fusarium]]
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	**Allergic fungal sinusitis: [[Aspergillus]], [[Bipolaris]], [[Curvularia]], [[Dreschlera]]		**Allergic fungal sinusitis: [[Aspergillus]], [[Bipolaris]], [[Curvularia]], [[Dreschlera]]

	=== Risk Factors ===		===Risk Factors===

	* Immunocompromise, including [[solid organ transplantation]] and [[hematopoietic stem cell transplantation]]		*Immunocompromise, including [[solid organ transplantation]] and [[hematopoietic stem cell transplantation]]
	* [[Diabetes mellitus]]		*[[Diabetes mellitus]]

	==Clinical Manifestations==		==Clinical Manifestations==

Aidan at 00:29, 16 August 2020

2020-08-16T00:29:55Z

← Older revision		Revision as of 00:29, 16 August 2020
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	== ~~Microbiology~~ ==		== Background ==

			===Microbiology===
	* Mucorales (50%)
	* Aspergillus (50%)
⚫	* Fusarium ~~(rare)~~

			*[[Zygomycetes]]: [[Mucor]], [[Rhizopus]]
⚫	== Clinical Manifestations ==
		⚫	*[[Fusarium]]
			*[[Pseudoallescheria boydii]]
			*[[Alternaria]]
			*[[Bipolaris]]
			*[[Cladophialophora]]
			*[[Curvularia]]
			*Non-invasive:
			**Mycetoma: [[Mucor]], [[Rhizopus]], [[Fusarium]], [[Pseudoallescheria bpydii]], [[Alternaria]], [[Bipolaris]], [[Cladophialophora]], [[Curvularia]]
			**Allergic fungal sinusitis: [[Aspergillus]], [[Bipolaris]], [[Curvularia]], [[Dreschlera]]

			=== Risk Factors ===
⚫	* Difficult to distinguish from ~~bacteria~~
	* Risk factors: DM, solid organ transplant, hematologic transplant
⚫	* Edema and paresthesias are common
⚫	* NP scope normal in ~30%; black eschar in 50%

			* Immunocompromise, including [[solid organ transplantation]] and [[hematopoietic stem cell transplantation]]
⚫	== Management ==
			* [[Diabetes mellitus]]

		⚫	==Clinical Manifestations==
⚫	* CT for extrasinus invasion

⚫	** MRI is more sensitive
		⚫	*Difficult to distinguish from [[acute bacterial sinusitis]]
⚫	* Debridement
		⚫	*Edema and paresthesias are common
⚫	* Lipsomal amphotericin B 5 mg/kg
		⚫	*NP scope normal in ~30%; black eschar in 50%
⚫	** Every day of delay increases mortality

⚫	** 3 week induction, then switch to posaconazole or isuvaconazole for 3-6 months
		⚫	==Management==
⚫	* Decrease immunosuppression

		⚫	*CT for extrasinus invasion
		⚫	**MRI is more sensitive
		⚫	*Debridement
		⚫	*Lipsomal amphotericin B 5 mg/kg
		⚫	**Every day of delay increases mortality
		⚫	**3 week induction, then switch to posaconazole or isuvaconazole for 3-6 months
		⚫	*Decrease immunosuppression

	[[Category:Head and neck infections]]		[[Category:Head and neck infections]]

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-17T16:02:28Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 16:02, 17 July 2020
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	* Fusarium (rare)		* Fusarium (rare)

	== Clinical ~~Presentation~~ ==		== Clinical Manifestations ==

	* Difficult to distinguish from bacteria		* Difficult to distinguish from bacteria

Aidan at 15:23, 17 August 2019

2019-08-17T15:23:31Z

← Older revision		Revision as of 15:23, 17 August 2019
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	= Microbiology =		== Microbiology ==

	* Mucorales (50%)		* Mucorales (50%)
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	* Fusarium (rare)		* Fusarium (rare)

	= Clinical Presentation =		== Clinical Presentation ==

	* Difficult to distinguish from bacteria		* Difficult to distinguish from bacteria
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	* NP scope normal in ~30%; black eschar in 50%		* NP scope normal in ~30%; black eschar in 50%

	= Management =		== Management ==

	* CT for extrasinus invasion		* CT for extrasinus invasion

Aidan at 01:08, 15 August 2019

2019-08-15T01:08:10Z

← Older revision		Revision as of 01:08, 15 August 2019
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		⚫	= Microbiology =
	= Invasive fungal sinusitis =

⚫	== Microbiology ==

	* Mucorales (50%)		* Mucorales (50%)
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	* Fusarium (rare)		* Fusarium (rare)

	== Clinical Presentation ==		= Clinical Presentation =

	* Difficult to distinguish from bacteria		* Difficult to distinguish from bacteria
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	* NP scope normal in ~30%; black eschar in 50%		* NP scope normal in ~30%; black eschar in 50%

	== Management ==		= Management =

	* CT for extrasinus invasion		* CT for extrasinus invasion
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	** 3 week induction, then switch to posaconazole or isuvaconazole for 3-6 months		** 3 week induction, then switch to posaconazole or isuvaconazole for 3-6 months
	* Decrease immunosuppression		* Decrease immunosuppression

			[[Category:Head and neck infections]]

Aidan: Aidan moved page Head and neck Invasive fungal sinusitis to Invasive fungal sinusitis without leaving a redirect

2019-08-15T01:07:52Z

Aidan moved page Head and neck Invasive fungal sinusitis to Invasive fungal sinusitis without leaving a redirect

← Older revision	Revision as of 01:07, 15 August 2019
(No difference)

Maintenance script: Imported from text file

2019-08-11T18:05:52Z

Imported from text file

New page

= Invasive fungal sinusitis =

== Microbiology ==

* Mucorales (50%)
* Aspergillus (50%)
* Fusarium (rare)

== Clinical Presentation ==

* Difficult to distinguish from bacteria
* Risk factors: DM, solid organ transplant, hematologic transplant
* Edema and paresthesias are common
* NP scope normal in ~30%; black eschar in 50%

== Management ==

* CT for extrasinus invasion
** MRI is more sensitive
* Debridement
* Lipsomal amphotericin B 5 mg/kg
** Every day of delay increases mortality
** 3 week induction, then switch to posaconazole or isuvaconazole for 3-6 months
* Decrease immunosuppression