Intravenous immune globulin - Revision history

Aidan at 19:04, 8 April 2022

2022-04-08T19:04:45Z

← Older revision		Revision as of 19:04, 8 April 2022
Line 13:		Line 13:
	\|0.5 g/kg over 4 hours		\|0.5 g/kg over 4 hours
	\|-		\|-
	\|Immune thrombocytopenia, adult, acute		\|[[Immune thrombocytopenia]], adult, acute
	\|1 g/kg as a single dose; repeat if platelets do not increase by at least 30		\|1 g/kg as a single dose; repeat if platelets do not increase by at least 30
	\|-		\|-
	\|Immune thrombocytopenia, adult, chronic		\|[[Immune thrombocytopenia]], adult, chronic
	\|1-2 g/kg, as directed by a hematologist		\|1-2 g/kg, as directed by a hematologist
	\|-		\|-
	\|Immune thrombocytopenia, pediatric		\|[[Immune thrombocytopenia]], pediatric
	\|0.8 to 1 mg/kg as a single dose; can be repeated if no response		\|0.8 to 1 mg/kg as a single dose; can be repeated if no response
	\|-		\|-

Aidan at 19:04, 8 April 2022

2022-04-08T19:04:27Z

← Older revision		Revision as of 19:04, 8 April 2022
Line 4:		Line 4:
	!Dose and Duration		!Dose and Duration
	\|-		\|-
	\|Fetal/neonatal alloimmune thrombocytopenia		\|Fetal/neonatal alloimmune thrombocytopenia, maternal
			\|up to 2 g/kg weekly starting at 12-16 weeks gestation if previous fetus with intracranial hemorrhage, of up to 1 g/kg weekly starting at 20-26 weeks gestation otherwise
	\|		\|-
			\|Fetal/neonatal alloimmune thrombocytopenia, infant
			\|1 g/kg and reassess
	\|-		\|-
	\|Hemolytic disease of the fetus and newborn		\|Hemolytic disease of the fetus and newborn

Aidan: Created page with "== Dosing == {| class="wikitable" !Indication !Dose and Duration |- |Fetal/neonatal alloimmune thrombocytopenia | |- |Hemolytic disease of the fetus and newborn |0.5 g/kg over..."

2022-04-08T19:02:46Z

Created page with "== Dosing == {| class="wikitable" !Indication !Dose and Duration |- |Fetal/neonatal alloimmune thrombocytopenia | |- |Hemolytic disease of the fetus and newborn |0.5 g/kg over..."

New page

== Dosing ==
{| class="wikitable"
!Indication
!Dose and Duration
|-
|Fetal/neonatal alloimmune thrombocytopenia
|
|-
|Hemolytic disease of the fetus and newborn
|0.5 g/kg over 4 hours
|-
|Immune thrombocytopenia, adult, acute
|1 g/kg as a single dose; repeat if platelets do not increase by at least 30
|-
|Immune thrombocytopenia, adult, chronic
|1-2 g/kg, as directed by a hematologist
|-
|Immune thrombocytopenia, pediatric
|0.8 to 1 mg/kg as a single dose; can be repeated if no response
|-
|[[Post-transfusion purpura]]
|up to 2 g/kg divided over 2 to 5 consecutive days; repeat if necessary
|-
|[[Pemphigus vulgaris]]
|2 g/kg divided over 2 to 5 days every 4 weeks, then every 6 weeks after 6 months of therapy
|-
|[[Juvenile idiopathic inflammatory myopathy]]
|2 g/kg initial divided over 2 days as initial dose, followed by maintenance dose of up to 2 g/kg total
|-
|[[Kawasaki disease]]
|2 g/kg for 1 day; can be repeated if no response
|-
|Idiopathic inflammatory myopathy, including dermatomyositis and polymyositis
|up to 2 g/kg over 2 days monthly for 3 to 6 months, then continued at decreasing freuqncy over 2 years
|-
|[[Primary immunodeficiency|Primary]] and secondary immunodeficiency, adult
|0.4 to 0.6 g/kg every 3 to 4 weeks
|-
|[[Primary immunodeficiency|Primary]] and secondary immunodeficiency, pediatric
|0.3 to 0.6 g/kg every 3 to 4 weeks, targetting tough of 700 mg/dL
|-
|Hematopoietic stem cell transplant in primary immunodeficiency
|0.4-0.6 g/kg every 3 to 4 weeks
|-
|Kidney transplant from living donor to whom the patient is sensitized
|2 g/kg monthly for 4 months
|-
|Pre-transplant heart
|up to 1 g/kg monthly until transplant
|-
|Peri-transplant heart, lung, kidney, or pancreas
|1 g/kg in divided doses with a course of plasmapheresis
|-
|Post-transplant, acute
|1 g/kg/dose, can be divided if also getting plasmaphereesis
|-
|Post-transplant, chronic
|1 g/kg monthly
|-
|[[Streptococcal toxic shock syndrome]]
|1 g/kg on day one follower by 0.5 mg/kg daily for 2 days, or 0.15 g/kg daily for 5 days
|-
|[[Staphylococcal toxic shock syndrome]]
|1 g/kg on day one follower by 0.5 mg/kg daily for 2 days, or 0.15 g/kg daily for 5 days
|}
[[Category:Medications]]
[[Category:Hematology]]