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	<id>https://idwiki.org/index.php?action=history&amp;feed=atom&amp;title=Intrauterine_fetal_demise</id>
	<title>Intrauterine fetal demise - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://idwiki.org/index.php?action=history&amp;feed=atom&amp;title=Intrauterine_fetal_demise"/>
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	<updated>2026-05-13T01:10:47Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.43.8</generator>
	<entry>
		<id>https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;diff=5818&amp;oldid=prev</id>
		<title>Aidan at 02:19, 8 August 2020</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;diff=5818&amp;oldid=prev"/>
		<updated>2020-08-08T02:19:11Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;a href=&quot;https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;amp;diff=5818&amp;amp;oldid=5021&quot;&gt;Show changes&lt;/a&gt;</summary>
		<author><name>Aidan</name></author>
	</entry>
	<entry>
		<id>https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;diff=5021&amp;oldid=prev</id>
		<title>Aidan: Text replacement - &quot;Clinical Presentation&quot; to &quot;Clinical Manifestations&quot;</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;diff=5021&amp;oldid=prev"/>
		<updated>2020-07-18T11:51:53Z</updated>

		<summary type="html">&lt;p&gt;Text replacement - &amp;quot;Clinical Presentation&amp;quot; to &amp;quot;Clinical Manifestations&amp;quot;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 11:51, 18 July 2020&lt;/td&gt;
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		<author><name>Aidan</name></author>
	</entry>
	<entry>
		<id>https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;diff=4293&amp;oldid=prev</id>
		<title>Maintenance script: Imported from text file</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Intrauterine_fetal_demise&amp;diff=4293&amp;oldid=prev"/>
		<updated>2020-07-04T01:17:41Z</updated>

		<summary type="html">&lt;p&gt;Imported from text file&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Definition ==&lt;br /&gt;
&lt;br /&gt;
* Death of fetus in the uterus antepartum after 20 weeks gestation&lt;br /&gt;
** Also called intrauterine fetal demise (IUFD)&lt;br /&gt;
* Compared to stillbirth, where death is ante- or peripartum after 20 weeks gestation&lt;br /&gt;
** Fresh: delivered within 24h of fetal death&lt;br /&gt;
*** Zero degree: red skin suggests less than 8h dead&lt;br /&gt;
** Macerated: delivered after 24h of fetal death&lt;br /&gt;
*** First degree: peeling skin suggests more than 8h from death&lt;br /&gt;
*** Second degree: 2-7 days, effusion of skin&lt;br /&gt;
*** Third degree: &amp;amp;gt;7 days, yellow liver&lt;br /&gt;
* Spontaneous abortion if less than 20 weeks gestation&lt;br /&gt;
&lt;br /&gt;
== Etiology ==&lt;br /&gt;
&lt;br /&gt;
* Idiopathic, most commonly&lt;br /&gt;
* Maternal&lt;br /&gt;
** Diabetes&lt;br /&gt;
** Antiphospholid syndrome&lt;br /&gt;
** TORCH syndrome&lt;br /&gt;
** Preeclampsia&lt;br /&gt;
** Quite rinse rupture&lt;br /&gt;
** Porphyria&lt;br /&gt;
* Fetal&lt;br /&gt;
** Multiple gestation&lt;br /&gt;
** Growth restriction&lt;br /&gt;
** Hydrocephalus&lt;br /&gt;
* Placental&lt;br /&gt;
** Abruption&lt;br /&gt;
** Insufficiency&lt;br /&gt;
&lt;br /&gt;
== Risk factors ==&lt;br /&gt;
&lt;br /&gt;
* African-American&lt;br /&gt;
* Maternal infertility&lt;br /&gt;
* Maternal age &amp;amp;gt;40 years&lt;br /&gt;
* Male fetus&lt;br /&gt;
* Multiple gestation&lt;br /&gt;
* Multiparty&lt;br /&gt;
&lt;br /&gt;
== Clinical Presentation ==&lt;br /&gt;
&lt;br /&gt;
* Decreased fetal movement&lt;br /&gt;
* Absent fetal heart beat&lt;br /&gt;
&lt;br /&gt;
== Investigations ==&lt;br /&gt;
&lt;br /&gt;
* Ultrasound for diagnosis&lt;br /&gt;
** Spalding sign: overlapping fetal skull bones&lt;br /&gt;
** Robert sign: gas in the heart and vessels&lt;br /&gt;
* Assess for DIC&lt;br /&gt;
** Platelets&lt;br /&gt;
** Fibrinogen&lt;br /&gt;
** INR/PTT&lt;br /&gt;
* To investigate etiology&lt;br /&gt;
** CBC&lt;br /&gt;
** Blood glucose or HbA1c&lt;br /&gt;
** Lupus anticoagulant&lt;br /&gt;
** VDRL and TORCH screen&lt;br /&gt;
** Placental culture&lt;br /&gt;
* Examine the fetus after delivery for signs of trisomies, hydrocephalus&lt;br /&gt;
** X-ray&lt;br /&gt;
** MRI&lt;br /&gt;
** Autopsy&lt;br /&gt;
&lt;br /&gt;
== Management ==&lt;br /&gt;
&lt;br /&gt;
* Diagnose with ultrasound&lt;br /&gt;
* Assess risk of DIC&lt;br /&gt;
* Deliver the fetus, preferably vaginally&lt;br /&gt;
** Induction (preferred)&lt;br /&gt;
*** First-line:&lt;br /&gt;
**** Misoprostol 25-50mcg q4&lt;br /&gt;
**** If no progress after 24h, consider Caesarian section&lt;br /&gt;
*** Second-line: oxytocin&lt;br /&gt;
** Expectant management&lt;br /&gt;
*** Expected to deliver in 1-2 weeks&lt;br /&gt;
*** Counsel the patient&lt;br /&gt;
*** Follow coagulation status to monitor for DIC&lt;br /&gt;
* Evaluate the fetus after delivery&lt;br /&gt;
* Counsel and reassure the parents&lt;br /&gt;
* Prevent breast milk&lt;br /&gt;
** First-line: carbigoline once&lt;br /&gt;
** Last-line: bromocriptine&lt;br /&gt;
&lt;br /&gt;
[[Category:Obstetrical medicine]]&lt;/div&gt;</summary>
		<author><name>Maintenance script</name></author>
	</entry>
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