Aidan: Created page with "== Background == * Decreased or absent levels of serum IgA (<7 mg/dL) with normal IgG and IgM levels in a person age 4 years or older * Partial deficiency is when serum level..."

2020-09-14T00:43:46Z

Created page with "== Background == * Decreased or absent levels of serum IgA (<7 mg/dL) with normal IgG and IgM levels in a person age 4 years or older * Partial deficiency is when serum level..."

New page

== Background ==

* Decreased or absent levels of serum IgA (<7 mg/dL) with normal IgG and IgM levels in a person age 4 years or older
* Partial deficiency is when serum levels are ≥7 mg/dL but still more than 2 standard deviations below normal

=== Epidemiology ===

* Most common primary immunodeficiency, though mostly asymptomatic
* More common in European, African, and Middle Eastern populations, and less common in Asian populations

== Clinical Manifestations ==

* Mostly asymptomatic (85-90%)
* Recurrent sinopulmonary and gastrointestinal infections
* Increased risk of allergy, autoimmune diseases, and [[celiac disease]]
* Risk of anaphylaxis to [[IVIg]]
* Can progress to [[specific antibody deficiency]] or [[CVID]]

[[Category:Primary immunodeficiencies]]

IgA deficiency - Revision history

Aidan: Created page with "== Background == * Decreased or absent levels of serum IgA (<7 mg/dL) with normal IgG and IgM levels in a person age 4 years or older * Partial deficiency is when serum level..."