Hidradenitis suppurativa - Revision history

Aidan at 14:53, 3 July 2025

2025-07-03T14:53:34Z

← Older revision		Revision as of 14:53, 3 July 2025
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	* '''Stage II''': recurrent abscesses with skin tunnels and scarring, single or multiple widely separated lesions		* '''Stage II''': recurrent abscesses with skin tunnels and scarring, single or multiple widely separated lesions
	* '''Stage III''': diffuse or almost diffuse involvement, or multiple interconnected skin tunnels and abscesses across the entire area		* '''Stage III''': diffuse or almost diffuse involvement, or multiple interconnected skin tunnels and abscesses across the entire area

			== Differential Diagnosis ==

			* Clinically, consider: follicular pyoderma (including folliculitis, furuncles, and carbuncles), [[granuloma inguinale]], noduloulcerative [[syphilis]], [[Tuberculosis\|tuberculous abscess]], [[actinomycosis]], [[lymphogranuloma venereum]], [[acne vulgaris]], epidermoid/dermoid/pilonidal/Bartholin cysts, [[Crohn disease]]
			* Histopathologically, consider: granulomatous disease (including [[Crohn disease]], [[sarcoidosis]], [[Mycobacteria\|mycobacterial infections]]), chronic deep folliculitis, [[Langerhans cell histiocytosis]], folliculotropic [[mycosis fungoides]], [[pyoderma gangrenosum]], follicular rupture, and abscess

	== Management ==		== Management ==

Aidan: /* Management */

2025-07-03T14:50:17Z

Management

← Older revision		Revision as of 14:50, 3 July 2025
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	== Management ==		== Management ==

	* For mild disease, can consider topical [[clindamycin]] or oral [[tetracycline]]		* For mild disease, can consider topical [[clindamycin]] or oral [[tetracycline]] (as a trial for 2 to 3 months)
			** Can also consider [[spirolonactone]] and [[metformin]]
	* For mild to moderate disease, consider oral [[tetracycline]]		* For mild to moderate disease, consider oral [[tetracycline]]
	* For moderate to severe disease, particularly which does not respond to antibiotics, consider [[adalimumab]]		* For moderate to severe disease, particularly which does not respond to antibiotics, consider [[adalimumab]]

Aidan: /* Management */

2025-07-03T14:48:13Z

Management

← Older revision		Revision as of 14:48, 3 July 2025
Line 30:		Line 30:
	== Management ==		== Management ==

	* For mild disease, can consider topical clindamycin or oral tetracycline		* For mild disease, can consider topical [[clindamycin]] or oral [[tetracycline]]
	* For mild to moderate disease, consider oral tetracycline		* For mild to moderate disease, consider oral [[tetracycline]]
	* For moderate to severe disease, particularly which does not respond to antibiotics, consider [[adalimumab]]		* For moderate to severe disease, particularly which does not respond to antibiotics, consider [[adalimumab]]
	** Also [[infliximab]], [[secukinumab]], [[acitretin]]		** Also [[infliximab]], [[secukinumab]], [[acitretin]]

Aidan: Created page with "== Background == * Idiopathic chronic inflammatory skin condition * Also known as acne inversa or Verneuil disease === Pathophysiology === * Chronic follicular occlusive disease involving the follicular portion of the folliculopilosebaceous units === Epidemiology === * Onset between puberty and age 40 * Slight female predominance * Increased risk of metabolic syndrome * Possible association with Crohn disease (more than ulcerative colitis) * Member of th..."

2023-10-25T18:22:14Z

Created page with "== Background == * Idiopathic chronic inflammatory skin condition * Also known as acne inversa or Verneuil disease === Pathophysiology === * Chronic follicular occlusive disease involving the follicular portion of the folliculopilosebaceous units === Epidemiology === * Onset between puberty and age 40 * Slight female predominance * Increased risk of metabolic syndrome * Possible association with Crohn disease (more than ulcerative colitis) * Member of th..."

New page

== Background ==

* Idiopathic chronic inflammatory skin condition
* Also known as acne inversa or Verneuil disease

=== Pathophysiology ===

* Chronic follicular occlusive disease involving the follicular portion of the folliculopilosebaceous units

=== Epidemiology ===

* Onset between puberty and age 40
* Slight female predominance
* Increased risk of [[metabolic syndrome]]
* Possible association with [[Crohn disease]] (more than [[ulcerative colitis]])
* Member of the follicular occlusion tetrad, including acne conglobata, dissecting cellulitis of the scalp, and pilonidal sinus
* May be associated with autoimmune or inflammatory disorders, some malignancies, and genetic disorder

== Clinical Manifestations ==

* Lesions mimic recurrent boils or furuncles
* Predominantly in intertriginous areas, with axillae being most common, but also affecting inguinal area, inner thighs, perianal and perineal areas, mammary and inframammary areas, buttocks, pubic region, scrotum, vulva, trunk, and occasionally the scalp and retroauricular areas

=== Hurley Clinical Staging ===

* '''Stage I''': abscess formation (single or multiple) without skin tunnels or cicatrization/scarring
* '''Stage II''': recurrent abscesses with skin tunnels and scarring, single or multiple widely separated lesions
* '''Stage III''': diffuse or almost diffuse involvement, or multiple interconnected skin tunnels and abscesses across the entire area

== Management ==

* For mild disease, can consider topical clindamycin or oral tetracycline
* For mild to moderate disease, consider oral tetracycline
* For moderate to severe disease, particularly which does not respond to antibiotics, consider [[adalimumab]]
** Also [[infliximab]], [[secukinumab]], [[acitretin]]

[[Category:Rheumatology]]
[[Category:Dermatology]]