Hepatitis B vaccine - Revision history

Aidan at 20:36, 28 February 2021

2021-02-28T20:36:16Z

@@ Line 1: / Line 1: @@
 ==Indications==
-**persons with a history of sexually transmitted infections
+***persons who have unprotected sex with new partners
-**persons who engage in high-risk sexual practices
+***persons with a history of sexually transmitted infections
-**men who have sex with men (MSM)
+***persons who engage in high-risk sexual practices
 *Any person who wishes to decrease their risk of HB.

Aidan: /* Post-Vaccine Serology */

2021-02-23T21:59:58Z

Post-Vaccine Serology

← Older revision		Revision as of 21:59, 23 February 2021
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	== Indications ==		==Indications==

	* Adults and children who have immigrated to Canada from areas where there is a [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png high prevalence of HB].		*Adults and children who have immigrated to Canada from areas where there is a [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png high prevalence of HB].
	* Children born in Canada whose families have emigrated from areas where there is a [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png high prevalence of HB] and who may be exposed to HB carriers through their extended families or when visiting their family’s country of origin.		*Children born in Canada whose families have emigrated from areas where there is a [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png high prevalence of HB] and who may be exposed to HB carriers through their extended families or when visiting their family’s country of origin.
	* Children and workers in child care settings in which there is a child or worker who has acute HB or is a HB carrier.		*Children and workers in child care settings in which there is a child or worker who has acute HB or is a HB carrier.
	* Household and sexual contacts of acute HB cases and HB carriers.		*Household and sexual contacts of acute HB cases and HB carriers.
	* Household or close contacts of children adopted from [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png HB-endemic countries] if the adopted child is HBsAg positive.		*Household or close contacts of children adopted from [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png HB-endemic countries] if the adopted child is HBsAg positive.
	* Populations or communities in which HB is highly endemic.		*Populations or communities in which HB is highly endemic.
	* Residents and staff of institutions for the developmentally challenged.		*Residents and staff of institutions for the developmentally challenged.
	* Staff and inmates of correctional facilities.		*Staff and inmates of correctional facilities.
	* People with lifestyle risks for infection, including:		*People with lifestyle risks for infection, including:
	** persons who have unprotected sex with new partners		**persons who have unprotected sex with new partners
	** persons who have had more than one sexual partner in the previous 6 months		**persons who have had more than one sexual partner in the previous 6 months
	** persons with a history of sexually transmitted infections		**persons with a history of sexually transmitted infections
	** persons seeking evaluation or treatment for a sexually transmitted infection		**persons seeking evaluation or treatment for a sexually transmitted infection
	** persons who engage in high-risk sexual practices		**persons who engage in high-risk sexual practices
	** persons who use injection drugs		**persons who use injection drugs
	** men who have sex with men (MSM)		**men who have sex with men (MSM)
	* People with chronic liver disease from any cause, including those infected with hepatitis C. While these persons may not be at an increased risk of HB infection, they may be at risk of more severe disease if infection occurs.		*People with chronic liver disease from any cause, including those infected with hepatitis C. While these persons may not be at an increased risk of HB infection, they may be at risk of more severe disease if infection occurs.
	* Hemophiliacs and other people receiving repeated infusions of blood or blood products.		*Hemophiliacs and other people receiving repeated infusions of blood or blood products.
	* People with chronic renal disease, including those undergoing chronic dialysis (hemodialysis or peritoneal dialysis).		*People with chronic renal disease, including those undergoing chronic dialysis (hemodialysis or peritoneal dialysis).
	* People with congenital immunodeficiencies.		*People with congenital immunodeficiencies.
	* People who have undergone hematopoietic stem cell transplantation (HSCT) or are awaiting solid organ transplant.		*People who have undergone hematopoietic stem cell transplantation (HSCT) or are awaiting solid organ transplant.
	* HIV-infected person.		*HIV-infected person.
	* Travellers to [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png HB-endemic areas].		*Travellers to [http://gamapserver.who.int/mapLibrary/Files/Maps/Global_HepB_ITHRiskMap.png HB-endemic areas].
	* Health care workers, emergency service workers, and others with potential occupational exposure to blood, blood products and bodily fluids that may contain HB virus.		*Health care workers, emergency service workers, and others with potential occupational exposure to blood, blood products and bodily fluids that may contain HB virus.
	* Any person who wishes to decrease their risk of HB.		*Any person who wishes to decrease their risk of HB.

	== Dosing ==		==Dosing==

	*A higher dose of vaccine is required for:		*A higher dose of vaccine is required for:
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	*Can detect HBsAg in blood for 18 days after vaccination		*Can detect HBsAg in blood for 18 days after vaccination

	=== Post-Vaccine Serology ===		===Post-Vaccine Serology===

	*A cutoff of 10 IU/mL defines protective antibody titres		*A cutoff of 10 IU/mL defines protective antibody titres
	*About 5% are primary non-responders and never had positive titres; they are not immune		*About 5% are primary non-responders and never had positive titres; they are not immune
	*However, their titres may have waned over time but they maintain the ability to mount an antibody response once exposed		*However, their titres may have waned over time but they maintain the ability to mount an antibody response once exposed
			*Post-immunization serologic testing with anti-HBs titre should be done 1 to 6 months after completing the immunization schedule for:
			**Immunocompromised people
			**People with chronic kidney disease or who are on dialysis
			**People with advanced liver failure
			**Solid organ transplant candidates and recipients
			**Pregnant women at high risk of HB
			**People with potential percutaneous or mucosal exposure (delay for 6 months if they received HBIh)
			**Sexual and hosuehold contacts of acute cases and chronic carriers
			**Workers who require confirmation of immunity because of occupational exposure
			*Periodic monitoring is recommended for:
			**Immunocompromised people
			**People with chronic kidney disease or who are on dialysis (monitored annually)
	*Often need to revaccinate		*Often need to revaccinate

Aidan at 21:56, 23 February 2021

2021-02-23T21:56:35Z

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 *A higher dose of vaccine is required for:
 **[[Chronic kidney disease]]
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 **[[Hematopoietic stem cell transplantation]]
 *Can detect HBsAg in blood for 18 days after vaccination
 [[Category:Viral hepatitis]]

Aidan: Text replacement - "([Ss])olid-organ" to "$1olid organ"

2020-08-07T03:03:17Z

Text replacement - "([Ss])olid-organ" to "$1olid organ"

← Older revision		Revision as of 03:03, 7 August 2020
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	**[[HIV]]		**[[HIV]]
	**[[Primary immunodeficiency]]		**[[Primary immunodeficiency]]
	**[[Solid-organ transplantation]]		**[[Solid organ transplantation]]
	**[[Hematopoietic stem cell transplantation]]		**[[Hematopoietic stem cell transplantation]]
	*Can detect HBsAg in blood for 18 days after vaccination		*Can detect HBsAg in blood for 18 days after vaccination

Aidan at 15:07, 6 August 2020

2020-08-06T15:07:36Z

← Older revision		Revision as of 15:07, 6 August 2020
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			*A higher dose of vaccine is required for:
⚫	* Can detect HBsAg in blood for 18 days after vaccination
			**[[Chronic kidney disease]]
			**[[Hemodialysis]]
			**[[HIV]]
			**[[Primary immunodeficiency]]
			**[[Solid-organ transplantation]]
			**[[Hematopoietic stem cell transplantation]]
		⚫	*Can detect HBsAg in blood for 18 days after vaccination

	[[Category:Viral hepatitis]]		[[Category:Viral hepatitis]]

Aidan: Created page with "* Can detect HBsAg in blood for 18 days after vaccination Category:Viral hepatitis Category:Infectious diseases Category:Vaccination"

2020-08-06T15:06:09Z

Created page with "* Can detect HBsAg in blood for 18 days after vaccination Category:Viral hepatitis Category:Infectious diseases Category:Vaccination"

New page

* Can detect HBsAg in blood for 18 days after vaccination

[[Category:Viral hepatitis]]
[[Category:Infectious diseases]]
[[Category:Vaccination]]