Haemophilus ducreyi - Revision history

Aidan at 16:16, 3 December 2020

2020-12-03T16:16:24Z

← Older revision		Revision as of 16:16, 3 December 2020
Line 1:		Line 1:
	== Background ==		==Background==

	* Causes '''chancroid'''		*Causes '''chancroid'''

	=== Microbiology ===		===Microbiology===

	* Fastidious Gram-negative bacillus		*Fastidious Gram-negative bacillus

	=== Epidemiology ===		===Epidemiology===

	* Present worldwide		*Present worldwide
	* Endemic when sex workers, for example, are pressured to have sex with multiple partners despite active genital lesions		*Endemic when sex workers, for example, are pressured to have sex with multiple partners despite active genital lesions

	== Clinical Manifestations ==		==Clinical Manifestations==

	* Presents initially with a papule at the site of inoculation, progressing to pustules, which rupture into painful, purulent, and shallow ulcers		*Presents initially with a papule at the site of inoculation, progressing to pustules, which rupture into painful, purulent, and shallow ulcers
	** Ulcer base often bleeds		**Ulcer base often bleeds
	** In men, lesions are more common on the prepuce, coronal sulcus, or penile shaft		**In men, lesions are more common on the prepuce, coronal sulcus, or penile shaft
	** In women, lesions occur more commonly on external genitalia, but can also occur within the vagina or on the cervix		**In women, lesions occur more commonly on external genitalia, but can also occur within the vagina or on the cervix
	* Often multiple ulcers		*Often multiple ulcers
	* May have associated painful [[lymphadenitis]], which can drain		*May have associated painful [[lymphadenitis]], which can drain

	== Diagnosis ==		==Diagnosis==

			*Not culturable
	* Culture for ''Haemophilus ducreyi'' from swab of lesion, or PCR if available
			*PCR if available
⚫	* Rule out other causes as appropriate with NAAT or PCR
			*Most commonly diagnosed with tissue biopsy using Giemsa or Wright stains
		⚫	*Rule out other causes as appropriate with NAAT or PCR

	== Management ==		==Management==

	* First-line: [[Is treated by::ciprofloxacin]] 500 mg PO once		*First-line: [[Is treated by::ciprofloxacin]] 500 mg PO once
	* Alternatives: [[Is treated by::erythromycin]] 500 mg PO tid for 7 days, [[Is treated by::azithromycin]] 1 g PO once, or [[Is treated by::ceftriaxone]] 250 mg IM once		*Alternatives: [[Is treated by::erythromycin]] 500 mg PO tid for 7 days, [[Is treated by::azithromycin]] 1 g PO once, or [[Is treated by::ceftriaxone]] 250 mg IM once
	* Rule out other STIs		*Rule out other STIs

	{{DISPLAYTITLE:''Haemophilus ducreyi''}}		{{DISPLAYTITLE:''Haemophilus ducreyi''}}

Aidan: /* Management */

2020-07-30T22:58:58Z

Management

← Older revision		Revision as of 22:58, 30 July 2020
Line 28:		Line 28:
	== Management ==		== Management ==

	* First-line: [[Is treated by::~~Ciprofloxacin~~]] 500 mg PO once		* First-line: [[Is treated by::ciprofloxacin]] 500 mg PO once
	* Alternatives: [[Is treated by::erythromycin]] 500 mg PO tid for 7 days, [[Is treated by::azithromycin]] 1 g PO once, or [[Is treated by::ceftriaxone]] 250 mg IM once		* Alternatives: [[Is treated by::erythromycin]] 500 mg PO tid for 7 days, [[Is treated by::azithromycin]] 1 g PO once, or [[Is treated by::ceftriaxone]] 250 mg IM once
	* Rule out other STIs		* Rule out other STIs

Aidan at 22:58, 30 July 2020

2020-07-30T22:58:50Z

← Older revision		Revision as of 22:58, 30 July 2020
Line 32:		Line 32:
	* Rule out other STIs		* Rule out other STIs

	{{DISPLAYTITLE:''Haemophilus ducreyi}}		{{DISPLAYTITLE:''Haemophilus ducreyi''}}
	[[Category:Infectious diseases]]		[[Category:Infectious diseases]]
	[[Category:Sexually-transmitted infections]]		[[Category:Sexually-transmitted infections]]

Aidan at 22:58, 30 July 2020

2020-07-30T22:58:39Z

← Older revision		Revision as of 22:58, 30 July 2020
Line 32:		Line 32:
	* Rule out other STIs		* Rule out other STIs

			{{DISPLAYTITLE:''Haemophilus ducreyi}}
	[[Category:Infectious diseases]]		[[Category:Infectious diseases]]
	[[Category:Sexually-transmitted infections]]		[[Category:Sexually-transmitted infections]]

Aidan: Created page with "== Background == * Causes '''chancroid''' === Microbiology === * Fastidious Gram-negative bacillus === Epidemiology === * Present worldwide * Endemic when sex workers, fo..."

2020-07-30T18:24:05Z

Created page with "== Background == * Causes '''chancroid''' === Microbiology === * Fastidious Gram-negative bacillus === Epidemiology === * Present worldwide * Endemic when sex workers, fo..."

New page

== Background ==

* Causes '''chancroid'''

=== Microbiology ===

* Fastidious Gram-negative bacillus

=== Epidemiology ===

* Present worldwide
* Endemic when sex workers, for example, are pressured to have sex with multiple partners despite active genital lesions

== Clinical Manifestations ==

* Presents initially with a papule at the site of inoculation, progressing to pustules, which rupture into painful, purulent, and shallow ulcers
** Ulcer base often bleeds
** In men, lesions are more common on the prepuce, coronal sulcus, or penile shaft
** In women, lesions occur more commonly on external genitalia, but can also occur within the vagina or on the cervix
* Often multiple ulcers
* May have associated painful [[lymphadenitis]], which can drain

== Diagnosis ==

* Culture for ''Haemophilus ducreyi'' from swab of lesion, or PCR if available
* Rule out other causes as appropriate with NAAT or PCR

== Management ==

* First-line: [[Is treated by::Ciprofloxacin]] 500 mg PO once
* Alternatives: [[Is treated by::erythromycin]] 500 mg PO tid for 7 days, [[Is treated by::azithromycin]] 1 g PO once, or [[Is treated by::ceftriaxone]] 250 mg IM once
* Rule out other STIs

[[Category:Infectious diseases]]
[[Category:Sexually-transmitted infections]]