HSV in pregnancy - Revision history

Aidan: /* Management */

2020-07-21T02:30:19Z

Management

@@ Line 38: / Line 38: @@
 ==Clinical Manifestations==
-*Can also cause [[congenital HSV]] in the fetus
+*Can cause [[congenital HSV]] in the fetus
 ==Management==

Aidan: /* Management */

2020-07-21T01:57:45Z

Management

← Older revision		Revision as of 01:57, 21 July 2020
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	== Background ==		==Background==

	*Infection with [[herpes simplex virus]] during pregnancy		*Infection with [[herpes simplex virus]] during pregnancy

	=== Epidemiology ===		===Epidemiology===

	*Risk of perinatal transmission varies by maternal serostatus relative to the active infection at the time of delivery		*Risk of perinatal transmission varies by maternal serostatus relative to the active infection at the time of delivery
	** Newly acquired		**Newly acquired
	*** First-episode primary infection (mother has no serum antibodies to HSV-1 or -2 at onset): risk of transmission is about 60%		***First-episode primary infection (mother has no serum antibodies to HSV-1 or -2 at onset): risk of transmission is about 60%
	*** First-episode nonprimary infection (mother has a new infection with one HSV type in the presence of antibodies to the other type): risk of transmission is less than 30%		***First-episode nonprimary infection (mother has a new infection with one HSV type in the presence of antibodies to the other type): risk of transmission is less than 30%
	** Recurrent (mother has pre-existing antibodies to the HSV type that is isolated from the genital tract): risk of transmission is less than 2%		**Recurrent (mother has pre-existing antibodies to the HSV type that is isolated from the genital tract): risk of transmission is less than 2%

	{\| class="wikitable"		{\| class="wikitable"
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	\|}		\|}

	== Clinical Manifestations ==		==Clinical Manifestations==

	*If acquired during pregnancy, HSV can cause spontaneous abortion and should be treated for 7 to 10 days		*If acquired during pregnancy, HSV can cause spontaneous abortion and should be treated for 7 to 10 days
	*Can also cause [[congenital HSV]] in the fetus		*Can also cause [[congenital HSV]] in the fetus

	== Management ==		==Management==

	*If HSV-2-positive, then if there are lesions or PCR-positivity at time of labour, could consider Cesarean section		*If HSV-2-positive, then if there are lesions or PCR-positivity at time of labour, could consider Cesarean section
			*For the management of the neonate post-partum, refer to [[neonatal HSV]]

Aidan: added Epidemiology and restructured headers

2020-07-21T01:51:52Z

added Epidemiology and restructured headers

@@ Line 1: / Line 1: @@
 {| class="wikitable"
-! Serology      !! Neonatal HSV per 100,000 births
+!Risk of perinatal transmission!!Neonatal HSV per 100,000 births
 |-
-| Negative      || 54
+|Negative
 |-
-| HSV-1 only    || 26
+|HSV-1 only
 |-
-| HSV-2 only    || 35
+|HSV-2 only
 |-
-| HSV-1 + HSV-2 || 12
+|HSV-1 + HSV-2
 |-
-| HSV-2 ± HSV-1 || 22
+|HSV-2 ± HSV-1
 |}

Aidan: Created page with "* Infection with herpes simplex virus during pregnancy * Highest risk for transmission is perinatal primary infection {| class="wikitable" |+ Risk of neonatal acquisition..."

2019-10-17T00:32:44Z

Created page with "* Infection with herpes simplex virus during pregnancy * Highest risk for transmission is perinatal primary infection {| class="wikitable" |+ Risk of neonatal acquisition..."

New page

* Infection with [[herpes simplex virus]] during pregnancy
* Highest risk for transmission is perinatal primary infection

{| class="wikitable"
|+ Risk of neonatal acquisition of HSV based on maternal serostatus
! Serology !! Neonatal HSV per 100,000 births
|-
| Negative || 54
|-
| HSV-1 only || 26
|-
| HSV-2 only || 35
|-
| HSV-1 + HSV-2 || 12
|-
| HSV-2 ± HSV-1 || 22
|}

* If acquired during pregnancy, HSV can cause spontaneous abortion and should be treated for 7 to 10 days
* If HSV-2-positive, then if there are lesions or PCR-positivity at time of labour, could consider Cesarean section