https://idwiki.org/index.php?action=history&feed=atom&title=Euthyroid_sick_syndrome 2026-05-13T00:34:17Z Revision history for this page on the wiki MediaWiki 1.43.8 https://idwiki.org/index.php?title=Euthyroid_sick_syndrome&diff=7793&oldid=prev 2021-04-19T01:27:39Z

<p>Created page with &quot;== Background == * Refers to abnormal thyroid function tests in the context of systemic non-thyroidal illness, surgery, or fasting * Transient abnormalities of thyroid functi...&quot;</p> <p><b>New page</b></p><div>== Background ==<br /> <br /> * Refers to abnormal thyroid function tests in the context of systemic non-thyroidal illness, surgery, or fasting<br /> * Transient abnormalities of thyroid function tests are seen in many hospitalized patients<br /> * May be classified as<br /> ** Low T3 syndrome<br /> ** Low T3/low T4 syndrome<br /> ** High T4 syndrome<br /> ** Other abnormalities<br /> <br /> == Clinical Presentation ==<br /> <br /> * Admitted to hospital for non-thyroidal illness or surgery<br /> ** Most common in patients with severe illness<br /> * Thyroid function tests are abnormal<br /> ** Most commonly low free T3 with normal free T4 and TSH (70% of hospitalized patients)<br /> ** Low T3 and low T4 is seen in severely or critically ill patients and portends a poor prognosis<br /> *** One mechanism is decreased TSH in response to [[corticosteroids]] and [[dopamine]]<br /> ** High total T4 is seen in patients with elevated TBG, as seen in [[chronic hepatitis]], [[primary biliary cirrhosis]], and [[acute intermittent porphyria]]<br /> ** High free and total T4 may be seen in patients treated with [[amiodarone]] or given CT contrast agents<br /> ** Treatment with [[heparin]] can cause a false laboratory measurement of elevated free T4<br /> <br /> == Further Reading ==<br /> <br /> * Euthyroid Sick Syndrome: Is It a Misnomer? &#039;&#039;J Clin Endocrinol Metabol&#039;&#039;. 1997;82(2):329–334. doi: [https://doi.org/10.1210/jcem.82.2.3745 10.1210/jcem.82.2.3745]<br /> <br /> [[Category:Endocrinology]]</div>

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