https://idwiki.org/index.php?action=history&feed=atom&title=Eosinophilic_cellulitisEosinophilic cellulitis - Revision history2026-04-28T19:25:25ZRevision history for this page on the wikiMediaWiki 1.43.8https://idwiki.org/index.php?title=Eosinophilic_cellulitis&diff=11242&oldid=prevAidan: Created page with "== Background == * Idiopathic syndrome of eosinophilic infiltration into skin * Many proposed triggers but none definite == Clinical Manifestations == * Sudden onset large, inflamed edematous patches, often with vesicles or bullae mimicking cellulitis * Often preceded by pruritus or burning * Often on trunk and extremities * Fevers may be absent or low-grade * Patches evolve over days, and can have central healing while border becomes purple * Patches regress with..."2025-09-08T18:13:16Z<p>Created page with "== Background == * Idiopathic syndrome of eosinophilic infiltration into skin * Many proposed triggers but none definite == Clinical Manifestations == * Sudden onset large, inflamed edematous patches, often with vesicles or bullae mimicking <a href="/Cellulitis" title="Cellulitis">cellulitis</a> * Often preceded by pruritus or burning * Often on trunk and extremities * Fevers may be absent or low-grade * Patches evolve over days, and can have central healing while border becomes purple * Patches regress with..."</p>
<p><b>New page</b></p><div>== Background ==<br />
<br />
* Idiopathic syndrome of eosinophilic infiltration into skin<br />
* Many proposed triggers but none definite<br />
<br />
== Clinical Manifestations ==<br />
<br />
* Sudden onset large, inflamed edematous patches, often with vesicles or bullae mimicking [[cellulitis]]<br />
* Often preceded by pruritus or burning<br />
* Often on trunk and extremities<br />
* Fevers may be absent or low-grade<br />
* Patches evolve over days, and can have central healing while border becomes purple<br />
* Patches regress within about 10 days, with return to normal skin around 4 to 6 weeks<br />
* Typically relapses over months to years, though with good long-term prognosis<br />
<br />
== Diagnosis ==<br />
<br />
* Biopsy results can vary by age of lesion<br />
** Dermal infiltration of eosinophils, some with degranulation<br />
*** May be superficial, deep dermal, or hypodermal (e.g. eosinophilic panniculitis)<br />
** Later, "flame-figures" in mid to deep dermis, consisting of collagen fibres with eosinophilic granules<br />
** Eosinophils eventually disappear and are replaced by phagocytic granulomas<br />
** Should ''not'' show evidence of vasculitis<br />
* Peripheral eosinophilia in about 50% of patients<br />
<br />
== Management ==<br />
<br />
* Corticosteroids with prednisone 0.5 to 1 mg/kg/day followed by rapid taper<br />
* [[Dapsone]]<br />
* Antihistamines</div>Aidan