Ehrlichia - Revision history

Aidan at 14:03, 22 September 2022

2022-09-22T14:03:20Z

← Older revision		Revision as of 14:03, 22 September 2022
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	*''E. chaffeensis'' is primarily found in south-central and eastern North America		*''E. chaffeensis'' is primarily found in south-central and eastern North America
			**Rejected by NML for patients from Ontario without travel
	*'''Vectors''' are a variety of ticks:		*'''Vectors''' are a variety of ticks:
	**''E. chaffeensis'' is transmitted by ''[[Vector::Amblyomma americanum]]'' ticks (the Lone Star tick)		**''E. chaffeensis'' is transmitted by ''[[Vector::Amblyomma americanum]]'' ticks (the Lone Star tick)

2022-01-27T20:54:15Z

Aidan moved page Ehrlichia species to Ehrlichia over a redirect without leaving a redirect

← Older revision		Revision as of 20:54, 27 January 2022
(No difference)

2022-01-27T20:54:10Z

← Older revision		Revision as of 20:54, 27 January 2022
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	*Can use [[rifampin]] as second-line, for pregnant women and children		*Can use [[rifampin]] as second-line, for pregnant women and children

	{{DISPLAYTITLE:''Ehrlichia'' ~~species~~}}		{{DISPLAYTITLE:''Ehrlichia''}}
	[[Category:Rickettsioses]]		[[Category:Rickettsioses]]

2020-10-29T14:18:10Z

← Older revision		Revision as of 14:18, 29 October 2020
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			<br />
⚫	*Causes '''human monocytotropic ehrlichiosis''', aka. "Rocky Mountain '''spotless''' fever"

	==Background==		==Background==

		⚫	* Causes '''human monocytotropic ehrlichiosis''', aka. "Rocky Mountain '''spotless''' fever"

	===Microbiology===		===Microbiology===

2020-08-16T19:00:03Z

Epidemiology

← Older revision		Revision as of 19:00, 16 August 2020
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	**Of note, it is not transmitted transovarially in the ticks		**Of note, it is not transmitted transovarially in the ticks
	*'''Reservoirs'''		*'''Reservoirs'''
	**The main reservoir is [[~~Has reservoir~~::~~White~~-tailed deer]]		**The main reservoir is [[Reservoir::Odocoileus virginianus]] (white-tailed deer)
	**For ''E. chaffeensis'', others include humans, dogs, coyotes, and marsh deer		**For ''E. chaffeensis'', others include humans, dogs, coyotes, and marsh deer
	**For ''E. ewingii'', dogs, humans, and deer		**For ''E. ewingii'', dogs, humans, and deer

2020-08-16T18:59:11Z

Microbiology

2020-08-05T13:58:55Z

E. chaffeensis (human monocytotropic ehrlichiosis)

← Older revision		Revision as of 13:58, 5 August 2020
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	* Usually causes a mild-to-severe multisystem illness in immunocompetent		* Usually causes a mild-to-severe multisystem illness in immunocompetent
	** Can cause overwhelming infection in immunosuppressed, especially [[HIV/AIDS]]		** Can cause overwhelming infection in immunosuppressed, especially [[HIV/AIDS]]
	* Incubation period of 7 days		* Incubation period of [[Usual incubation period::7 days]]
	* [[Causes::Fever]], [[Causes::headache]], [[Causes::myalgias]], and [[Causes::malaise]] are most common		* [[Causes::Fever]], [[Causes::headache]], [[Causes::myalgias]], and [[Causes::malaise]] are most common
	* [[Causes::Nausea]] and [[Causes::vomiting]] in a half, and [[Causes::weight loss]]		* [[Causes::Nausea]] and [[Causes::vomiting]] in a half, and [[Causes::weight loss]]

2020-08-02T13:32:15Z

Text replacement - "Has vector::" to "Vector::"

← Older revision		Revision as of 13:32, 2 August 2020
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	* ''E. chaffeensis'' is primarily found in south-central and eastern North America		* ''E. chaffeensis'' is primarily found in south-central and eastern North America
	* '''Vectors''' are a variety of ticks:		* '''Vectors''' are a variety of ticks:
	** ''E. chaffeensis'' is transmitted by ''[[~~Has vector~~::Amblyomma americanum]]'' ticks (the Lone Star tick)		** ''E. chaffeensis'' is transmitted by ''[[Vector::Amblyomma americanum]]'' ticks (the Lone Star tick)
	** ''E. ewingii''is transmitted by [[~~Has vector~~::Amblyomma americanum]]'' and ''[[~~Has vector~~::Dermacentor variabilis]]''		** ''E. ewingii''is transmitted by [[Vector::Amblyomma americanum]]'' and ''[[Vector::Dermacentor variabilis]]''
	** ''E. muris'' is transmitted by ''[[~~Has vector~~::Ixodes persulcatus]]'' and ''[[~~Has vector~~::Haemaphysalis flava]]''		** ''E. muris'' is transmitted by ''[[Vector::Ixodes persulcatus]]'' and ''[[Vector::Haemaphysalis flava]]''
	** ''E. muris''-like agent is transmitted by ''[[~~Has vector~~::Ixodes scapularis]]''		** ''E. muris''-like agent is transmitted by ''[[Vector::Ixodes scapularis]]''
	** Of note, it is not transmitted transovarially in the ticks		** Of note, it is not transmitted transovarially in the ticks
	* '''Reservoirs'''		* '''Reservoirs'''

2020-07-21T01:52:44Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 01:52, 21 July 2020
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	** Increased TNF-alpha, IL 1-alpha and 1-beta, IL-6, IL-10, and defective Th1 cytokines (IFN-gamma and IL-2)		** Increased TNF-alpha, IL 1-alpha and 1-beta, IL-6, IL-10, and defective Th1 cytokines (IFN-gamma and IL-2)

	== Clinical ~~Presentation~~ ==		== Clinical Manifestations ==
	=== ''E. chaffeensis'' (human monocytotropic ehrlichiosis) ===		=== ''E. chaffeensis'' (human monocytotropic ehrlichiosis) ===
	* Usually causes a mild-to-severe multisystem illness in immunocompetent		* Usually causes a mild-to-severe multisystem illness in immunocompetent

2020-03-08T14:00:14Z

Microbiology: cleaned up

← Older revision		Revision as of 14:00, 8 March 2020
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	* Small, obligately intracellular Gram-negative bacteria		* Small, obligately intracellular Gram-negative bacteria
	* Related to ''[[Anaplasma]]'' and ''[[Rickettsia]]'' genera		* Related to ''[[Anaplasma]]'' and ''[[Rickettsia]]'' genera
			* Includes the following species:
	* ''E. chaffeensis'' is the most common cause of human infection		** '''''E. chaffeensis''''' is the most common cause of human infection
	* ''E. ewingii'', ''E. muris'', ''R. muris''-like agent, ''E. canis'', and ''E. ruminantium'' ~~can all cause human disease~~, with slightly different tick vectors and mammalian hosts		** Other species that can cause disease in humans includes '''''E. ewingii''''', '''''E. muris'''', '''''E. muris''-like agent''', '''''E. canis''''', and '''''E. ruminantium''''', with slightly different tick vectors and mammalian hosts
	* Cells have two ultrastructural forms: larger reticulate cells (RC) and small, dense core cells (DC)		* Cells have two ultrastructural forms: larger '''reticulate cells''' (RC) and small, '''dense core cells''' (DC)
	* Intracellularly, they form aggregates called '''morulae''' (mulberries)		* Intracellularly, they form aggregates called '''morulae''' (mulberries)