Aidan: Created page with "== Background == * Previously known as benign ethnic neutropenia * Polymorphisms in ACKR1 gene, which encodes Duffy antigen receptor for chemokines (DARC) * The mutations lead to neutrophils leaving circulation for tissue, resulting in lower peripheral blood neutrophil counts * The gene mutation is present in about 60 to 70% of people with African ancestry, and may have evolved to impair entry of Plasmodium vivax into RBCs * About 10% of people with DANC will have a..."

2022-11-02T16:29:09Z

Created page with "== Background == * Previously known as benign ethnic neutropenia * Polymorphisms in ACKR1 gene, which encodes Duffy antigen receptor for chemokines (DARC) * The mutations lead to neutrophils leaving circulation for tissue, resulting in lower peripheral blood neutrophil counts * The gene mutation is present in about 60 to 70% of people with African ancestry, and may have evolved to impair entry of Plasmodium vivax into RBCs * About 10% of people with DANC will have a..."

New page

== Background ==

* Previously known as benign ethnic neutropenia
* Polymorphisms in ACKR1 gene, which encodes Duffy antigen receptor for chemokines (DARC)
* The mutations lead to neutrophils leaving circulation for tissue, resulting in lower peripheral blood neutrophil counts
* The gene mutation is present in about 60 to 70% of people with African ancestry, and may have evolved to impair entry of [[Plasmodium vivax]] into RBCs
* About 10% of people with DANC will have an ANC less than 1.5

[[Category:Hematology]]

Duffy-null associated neutrophil count - Revision history