https://idwiki.org/index.php?action=history&feed=atom&title=Drug-induced_thrombotic_microangiopathy 2026-04-25T20:20:53Z Revision history for this page on the wiki MediaWiki 1.43.8 https://idwiki.org/index.php?title=Drug-induced_thrombotic_microangiopathy&diff=10704&oldid=prev 2024-09-19T17:39:14Z

<p>al-nouri2015dr</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:39, 19 September 2024</td> </tr><tr> <td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td> </tr> <tr> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* May present with a [[TTP]]- or [[HUS]]-like syndrome</div></td> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* May present with a [[TTP]]- or [[HUS]]-like syndrome</div></td> </tr> <tr> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Variable and unceratain pathophysiology; likely some immune-mediated and some directly toxic</div></td> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Variable and unceratain pathophysiology; likely some immune-mediated and some directly toxic</div></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Associations that are probably true include: [[bevacizumab]], [[cocaine]], [[Cyclosporine|'''cyclosporine''']], [[docetaxel]], [[everolimus]], [[gemcitabine]], [[interferon α]], [[interferon β]], [[interferon polycarboxylate]], [[mitomycin]], [[muromonab-CD3]], [[oxaliplatin]], [[penicillin]], [[pentostatin]], [[quetiapine]], [[Quinine|'''quinine''']], [[sirolimus]], [[sulfisoxazole]], [[sunitinib]], [[Tacrolimus|'''tacrolimus''']], [[trielina]], and [[vincristine]]<del style="font-weight: bold; text-decoration: none;">&lt;ref&gt;Al-Nouri ZL, Reese JA, Terrell DR, Vesely SK, George JN. Drug-induced thrombotic microangiopathy</del>:<del style="font-weight: bold; text-decoration: none;"> a systematic review of published reports. Blood. 2015 Jan 22;125(4)</del>:<del style="font-weight: bold; text-decoration: none;">616</del>-<del style="font-weight: bold; text-decoration: none;">8. doi: [https://doi.org/10.1182%2Fblood-2014-11-611335 10.1182/blood-2014-11-611335</del>]<del style="font-weight: bold; text-decoration: none;">. Epub 2014 Nov 20. PMID: [https://pubmed.ncbi.nlm.nih.gov/25414441 25414441]; PMCID: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304106/ PMC4304106</del>]<del style="font-weight: bold; text-decoration: none;">.&lt;/ref&gt;</del></div></td> <td class="diff-marker" data-marker="+"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>* Associations that are probably true include: [[bevacizumab]], [[cocaine]], [[Cyclosporine|'''cyclosporine''']], [[docetaxel]], [[everolimus]], [[gemcitabine]], [[interferon α]], [[interferon β]], [[interferon polycarboxylate]], [[mitomycin]], [[muromonab-CD3]], [[oxaliplatin]], [[penicillin]], [[pentostatin]], [[quetiapine]], [[Quinine|'''quinine''']], [[sirolimus]], [[sulfisoxazole]], [[sunitinib]], [[Tacrolimus|'''tacrolimus''']], [[trielina]], and [[vincristine]]<ins style="font-weight: bold; text-decoration: none;">[[CiteRef</ins>::<ins style="font-weight: bold; text-decoration: none;">al</ins>-<ins style="font-weight: bold; text-decoration: none;">nouri2015dr</ins>]]</div></td> </tr> <tr> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br /></td> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br /></td> </tr> <tr> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Further Reading ==</div></td> <td class="diff-marker"></td> <td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Further Reading ==</div></td> </tr> <!-- diff cache key site7_mediawiki:diff:1.41:old-9918:rev-10704:wikidiff2=table:1.13.0:bc2a06be --> </table>

Aidan https://idwiki.org/index.php?title=Drug-induced_thrombotic_microangiopathy&diff=9918&oldid=prev 2023-04-20T13:59:18Z

<p>Created page with &quot;== Background == * A <a href="/Thrombotic_microangiopathy" title="Thrombotic microangiopathy">thrombotic microangiopathy</a> caused by exposure to certain medications * May present with a <a href="/TTP" class="mw-redirect" title="TTP">TTP</a>- or <a href="/HUS" class="mw-redirect" title="HUS">HUS</a>-like syndrome * Variable and unceratain pathophysiology; likely some immune-mediated and some directly toxic * Associations that are probably true include: <a href="/Bevacizumab" title="Bevacizumab">bevacizumab</a>, <a href="/Cocaine" title="Cocaine">cocaine</a>, <a href="/index.php?title=Cyclosporine&amp;action=edit&amp;redlink=1" class="new" title="Cyclosporine (page does not exist)">&#039;&#039;&#039;cyclosporine&#039;&#039;&#039;</a>, <a href="/index.php?title=Docetaxel&amp;action=edit&amp;redlink=1" class="new" title="Docetaxel (page does not exist)">docetaxel</a>, <a href="/Everolimus" title="Everolimus">everolimus</a>, <a href="/index.php?title=Gemcitabine&amp;action=edit&amp;redlink=1" class="new" title="Gemcitabine (page does not exist)">gemcitabine</a>, <a href="/index.php?title=Interferon_%CE%B1&amp;action=edit&amp;redlink=1" class="new" title="Interferon α (page does not exist)">interferon α</a>, <a href="/index.php?title=Interferon_%CE%B2&amp;action=edit&amp;redlink=1" class="new" title="Interferon β (page does not exist)">interferon β</a>, <a href="/index.php?title=Interferon_polycarboxylate&amp;action=edit&amp;redlink=1" class="new" title="Interferon polycarboxylate (page does not exist)">interferon polycarboxylate</a>...&quot;</p> <p><b>New page</b></p><div>== Background ==<br /> <br /> * A [[thrombotic microangiopathy]] caused by exposure to certain medications<br /> * May present with a [[TTP]]- or [[HUS]]-like syndrome<br /> * Variable and unceratain pathophysiology; likely some immune-mediated and some directly toxic<br /> * Associations that are probably true include: [[bevacizumab]], [[cocaine]], [[Cyclosporine|&#039;&#039;&#039;cyclosporine&#039;&#039;&#039;]], [[docetaxel]], [[everolimus]], [[gemcitabine]], [[interferon α]], [[interferon β]], [[interferon polycarboxylate]], [[mitomycin]], [[muromonab-CD3]], [[oxaliplatin]], [[penicillin]], [[pentostatin]], [[quetiapine]], [[Quinine|&#039;&#039;&#039;quinine&#039;&#039;&#039;]], [[sirolimus]], [[sulfisoxazole]], [[sunitinib]], [[Tacrolimus|&#039;&#039;&#039;tacrolimus&#039;&#039;&#039;]], [[trielina]], and [[vincristine]]&lt;ref&gt;Al-Nouri ZL, Reese JA, Terrell DR, Vesely SK, George JN. Drug-induced thrombotic microangiopathy: a systematic review of published reports. Blood. 2015 Jan 22;125(4):616-8. doi: [https://doi.org/10.1182%2Fblood-2014-11-611335 10.1182/blood-2014-11-611335]. Epub 2014 Nov 20. PMID: [https://pubmed.ncbi.nlm.nih.gov/25414441 25414441]; PMCID: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304106/ PMC4304106].&lt;/ref&gt;<br /> <br /> == Further Reading ==<br /> <br /> * Drug-induced thrombotic microangiopathy: a systematic review of published reports. &#039;&#039;Blood&#039;&#039;. 2015 Jan 22;125(4):616-8. doi: [https://doi.org/10.1182/blood-2014-11-611335 10.1182/blood-2014-11-611335]. PMID: [[25414441]]; PMCID: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304106/ PMC4304106].<br /> <br /> [[Category:Thrombotic microangiopathies]]</div>

Aidan