Drug-drug interactions - Revision history

Aidan at 17:29, 20 August 2020

2020-08-20T17:29:46Z

← Older revision		Revision as of 17:29, 20 August 2020
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	\|}		\|}

	[[Category:~~Antimicrobials~~]]		[[Category:Medications]]

Aidan: linkified everything

2020-08-19T13:38:02Z

linkified everything

Show changes

Aidan at 13:29, 19 August 2020

2020-08-19T13:29:25Z

← Older revision		Revision as of 13:29, 19 August 2020
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	\|[[probenecid]]<br />[[sertraline]]<br />'''[[sulfamethoxazole]]'''<br />teniposide<br />'''[[voriconazole]]'''<br />zafirlukast		\|[[probenecid]]<br />[[sertraline]]<br />'''[[sulfamethoxazole]]'''<br />teniposide<br />'''[[voriconazole]]'''<br />zafirlukast
	\|'''[[rifampin]]'''<br />secorbarbital		\|'''[[rifampin]]'''<br />secorbarbital
	\|[[amitriptyline]]<br />[[celecoxib]]<br />[[diclofenac]]<br />[[fluoxetine]]<br />[[fluvastatin]]<br />[[glipizide]]<br />[[glyburide]]<br />[[ibuprofen~~]]<br />\|[[irbesartan]]<br />lornoxicam<br />[[losartan]]<br />[[meloxicam]]<br />nateglinide<br />[[omeprazole]]<br />[[phenytoin~~]]		\|[[amitriptyline]]<br />[[celecoxib]]<br />[[diclofenac]]<br />[[fluoxetine]]<br />[[fluvastatin]]<br />[[glipizide]]<br />[[glyburide]]<br />[[ibuprofen]]
			\|[[irbesartan]]<br />lornoxicam<br />[[losartan]]<br />[[meloxicam]]<br />nateglinide<br />[[omeprazole]]<br />[[phenytoin]]
	\|piroxicam<br />[[rosiglitazone]]<br />[[rosuvastatin]]<br />S-[[warfarin]]<br />tamoxifen<br />tolbutamide<br />torsemide		\|piroxicam<br />[[rosiglitazone]]<br />[[rosuvastatin]]<br />S-[[warfarin]]<br />tamoxifen<br />tolbutamide<br />torsemide
	\|-		\|-

Aidan at 13:25, 19 August 2020

2020-08-19T13:25:15Z

← Older revision		Revision as of 13:25, 19 August 2020
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	\|[[fluvoxamine]]<br />'''[[interferon]]'''<br />methoxsalen		\|[[fluvoxamine]]<br />'''[[interferon]]'''<br />methoxsalen
	\|[[Nicotine use disorder\|cigarette smoking]]<br />[[Cannabis use disorder\|marijuana smoking]]<br />[[modafinil]]<br />'''[[nafcillin]]'''		\|[[Nicotine use disorder\|cigarette smoking]]<br />[[Cannabis use disorder\|marijuana smoking]]<br />[[modafinil]]<br />'''[[nafcillin]]'''
	\|[[amitriptyline]]<br />[[caffeine]]<br />[[clomipramine]]<br />[[clozapine]]<br />[[cyclobenzaprine]]<br />[[estradiol]]<br />[[fluvoxamine]]		\|[[amitriptyline]]<br />[[caffeine]]<br />[[clomipramine]]<br />[[clozapine]]<br />[[cyclobenzaprine]]<br />[[estradiol]]<br />[[fluvoxamine]]<br />[[haloperidol]]
			\|mexiletine<br />[[naproxen]]<br />[[olanzapine]]<br />[[ondansetron]]<br />phenacetine<br />[[propranolol]]<br />riluzole<br />ropivacaine
	[[haloperidol]]
	\|mexiletine<br />[[naproxen]]<br />[[olanzapine]]

	[[ondansetron]]

	phenacetine<br />[[propranolol]]<br />riluzole

	ropivacaine
	\|tacrine<br />[[theophylline]]<br />[[tizanidine]]<br />[[verapamil]]<br />R-[[warfarin]]<br />zileuton<br />[[zolmitriptan]]		\|tacrine<br />[[theophylline]]<br />[[tizanidine]]<br />[[verapamil]]<br />R-[[warfarin]]<br />zileuton<br />[[zolmitriptan]]
	\|-		\|-
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	\|[[probenecid]]<br />[[sertraline]]<br />'''[[sulfamethoxazole]]'''<br />teniposide<br />'''[[voriconazole]]'''<br />zafirlukast		\|[[probenecid]]<br />[[sertraline]]<br />'''[[sulfamethoxazole]]'''<br />teniposide<br />'''[[voriconazole]]'''<br />zafirlukast
	\|'''[[rifampin]]'''<br />secorbarbital		\|'''[[rifampin]]'''<br />secorbarbital
	\|[[amitriptyline]]<br />[[celecoxib]]<br />[[diclofenac]]<br />[[fluoxetine]]<br />[[fluvastatin]]		\|[[amitriptyline]]<br />[[celecoxib]]<br />[[diclofenac]]<br />[[fluoxetine]]<br />[[fluvastatin]]<br />[[glipizide]]<br />[[glyburide]]<br />[[ibuprofen]]<br />\|[[irbesartan]]<br />lornoxicam<br />[[losartan]]<br />[[meloxicam]]<br />nateglinide<br />[[omeprazole]]<br />[[phenytoin]]
	[[glipizide]]<br />[[glyburide]]

	[[ibuprofen]]
	\|[[irbesartan]]<br />lornoxicam<br />[[losartan]]
	[[meloxicam]]<br />nateglinide<br />[[omeprazole]]<br />[[phenytoin]]
	\|piroxicam<br />[[rosiglitazone]]<br />[[rosuvastatin]]<br />S-[[warfarin]]<br />tamoxifen<br />tolbutamide<br />torsemide		\|piroxicam<br />[[rosiglitazone]]<br />[[rosuvastatin]]<br />S-[[warfarin]]<br />tamoxifen<br />tolbutamide<br />torsemide
	\|-		\|-
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	\|[[modafinil]]<br />[[omeprazole]]<br />oxcarbazepine<br />[[pantoprazole]]<br />[[probenecid]]<br />[[rabeprazole]]<br />ticlopidine<br />[[topiramate]]		\|[[modafinil]]<br />[[omeprazole]]<br />oxcarbazepine<br />[[pantoprazole]]<br />[[probenecid]]<br />[[rabeprazole]]<br />ticlopidine<br />[[topiramate]]
	\|[[carbamazepine]]<br />norethindrone<br />prednisone<br />'''[[rifampin]]'''		\|[[carbamazepine]]<br />norethindrone<br />prednisone<br />'''[[rifampin]]'''
	\|carisoprodol<br />'''[[chloramphenicol]]'''<br />[[citalopram]]<br />clomipramine<br />cyclophosphamide<br />esomeprazole<br />hexobarbital		\|carisoprodol<br />'''[[chloramphenicol]]'''<br />[[citalopram]]<br />clomipramine<br />cyclophosphamide<br />esomeprazole<br />hexobarbital<br />indomethacin
		⚫	\|[[lansoprazole]]<br />moclobemide<br />'''[[nelfinavir]]'''<br />nilutamide<br />[[omeprazole]]<br />[[pantoprazole]]<br />[[phenobarbital]]<br />[[phenytoin]]
	indomethacin
⚫	\|[[lansoprazole]]<br />moclobemide<br />'''[[nelfinavir]]'''<br />nilutamide
	[[omeprazole]]<br />[[pantoprazole]]<br />[[phenobarbital]]

	[[phenytoin]]
	\|primidone<br />[[progesterone]]<br />'''[[proguanil]]'''<br />[[propranolol]]<br />[[rabeprazole]]<br />teniposide<br />'''[[voriconazole]]'''		\|primidone<br />[[progesterone]]<br />'''[[proguanil]]'''<br />[[propranolol]]<br />[[rabeprazole]]<br />teniposide<br />'''[[voriconazole]]'''
	\|-		\|-
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	\|-		\|-
	\|CYP2D6		\|CYP2D6
	\|amiodarone<br />bupropion<br />celecoxib<br />chlorpheniramine<br />chlorpromazine<br />cimetidine<br />citalopram<br />clemastine<br />clomipramine<br />cocaine<br />diphenhydramine<br />doxepin<br />doxorubicin<br />duloxetine		\|amiodarone<br />bupropion<br />celecoxib<br />chlorpheniramine<br />chlorpromazine<br />cimetidine<br />citalopram<br />clemastine<br />clomipramine<br />cocaine<br />diphenhydramine<br />doxepin<br />doxorubicin<br />duloxetine<br />escitalopram
	escitalopram
	\|fluoxetine<br />hydroxyzine<br />metoclopramide<br />mibefradil<br />midodrine<br />moclobemide<br />paroxetine<br />perphenazine<br />quinidine<br />ranitidine<br />'''[[ritonavir]]'''<br />sertraline<br />terbinafine<br />ticlopidine		\|fluoxetine<br />hydroxyzine<br />metoclopramide<br />mibefradil<br />midodrine<br />moclobemide<br />paroxetine<br />perphenazine<br />quinidine<br />ranitidine<br />'''[[ritonavir]]'''<br />sertraline<br />terbinafine<br />ticlopidine
	\|dexamethasone<br />'''[[rifampin]]'''		\|dexamethasone<br />'''[[rifampin]]'''
	\|alprenolol<br />amitriptyline<br />amphetamine<br />aripiprazole<br />atomoxetine<br />carvedilol<br />chlorpheniramine<br />chlorpromazine<br />clomipramine<br />codeine		\|alprenolol<br />amitriptyline<br />amphetamine<br />aripiprazole<br />atomoxetine<br />carvedilol<br />chlorpheniramine<br />chlorpromazine<br />clomipramine<br />codeine
		⚫	\|debrisoquine<br />desipramine<br />dexfenfluramine<br />dextromethorphan<br />duloxetine<br />encainide<br />flecainide<br />fluoxetine<br />fluvoxamine<br />haloperidol
	\|debrisoquine
⚫	desipramine<br />dexfenfluramine<br />dextromethorphan<br />duloxetine

	encainide

	flecainide<br />fluoxetine<br />fluvoxamine<br />haloperidol
	\|imipramine<br />lidocaine<br />methoxyamphetamine<br />metoclopramide<br />paroxetine<br />perphenazine<br />propafenone<br />S-metoprolol<br />thioridazine<br />timolol		\|imipramine<br />lidocaine<br />methoxyamphetamine<br />metoclopramide<br />paroxetine<br />perphenazine<br />propafenone<br />S-metoprolol<br />thioridazine<br />timolol
	\|-		\|-
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	\|-		\|-
	\|CYP3A		\|CYP3A
	\|amiodarone<br />aprepitant<br />cimetidine<br />'''[[clarithromycin]]'''<br />'''[[cobicistat]]'''<br />'''[[delavirdine]]'''<br />diltiazem<br />'''[[elvitegravir]]'''<br />'''[[erythromycin]]'''<br />'''[[fluconazole]]'''<br />fluvoxamine<br />gestodene<br />imatinib		\|amiodarone<br />aprepitant<br />cimetidine<br />'''[[clarithromycin]]'''<br />'''[[cobicistat]]'''<br />'''[[delavirdine]]'''<br />diltiazem<br />'''[[elvitegravir]]'''<br />'''[[erythromycin]]'''<br />'''[[fluconazole]]'''<br />fluvoxamine<br />gestodene<br />imatinib<br />'''[[indinavir]]'''
	'''[[indinavir]]'''
	\|'''[[isavuconazonium]]'''<br />'''[[itraconazole]]'''<br />'''[[ketoconazole]]'''<br />mibefradil<br />mifepristone<br />nefazodone<br />'''[[nelfinavir]]'''<br />norfluoxetine<br />'''[[posaconazole]]'''<br />'''[[ritonavir]]'''<br />'''[[saquinavir]]'''<br />verapamil<br />'''[[voriconazole]]'''		\|'''[[isavuconazonium]]'''<br />'''[[itraconazole]]'''<br />'''[[ketoconazole]]'''<br />mibefradil<br />mifepristone<br />nefazodone<br />'''[[nelfinavir]]'''<br />norfluoxetine<br />'''[[posaconazole]]'''<br />'''[[ritonavir]]'''<br />'''[[saquinavir]]'''<br />verapamil<br />'''[[voriconazole]]'''
	\|barbiturates<br />carbamazepine<br />'''[[efavirenz]]'''<br />glucocorticoids<br />modafinil<br />nevirapine<br />oxcarbazepine<br />phenobarbital<br />phenytoin<br />pioglitazone<br />'''[[rifabutin]]'''<br />'''[[rifampin]]'''<br />St. John’s wort		\|barbiturates<br />carbamazepine<br />'''[[efavirenz]]'''<br />glucocorticoids<br />modafinil<br />nevirapine<br />oxcarbazepine<br />phenobarbital<br />phenytoin<br />pioglitazone<br />'''[[rifabutin]]'''<br />'''[[rifampin]]'''<br />St. John’s wort
	\|alfentanil<br />alprazolam<br />amlodipine<br />aprepitant<br />aripiprazole<br />'''[[artemisinin]]'''<br />astemizole<br />'''[[atazanavir]]'''<br />atorvastatin<br />'''[[bedaquiline]]'''<br />buspirone<br />cafergot<br />chlorpheniramine<br />cilostazol<br />'''[[clarithromycin]]'''<br />cocaine<br />cyclosporine<br />'''[[daclatasvir]]'''<br />'''[[dapsone]]'''<br />'''[[darunavir]]'''<br />dexamethasone<br />dextromethorphan<br />diltiazem<br />docetaxel<br />domperidone<br />'''[[elbasvir]]'''<br />eplerenone		\|alfentanil<br />alprazolam<br />amlodipine<br />aprepitant<br />aripiprazole<br />'''[[artemisinin]]'''<br />astemizole<br />'''[[atazanavir]]'''<br />atorvastatin<br />'''[[bedaquiline]]'''<br />buspirone<br />cafergot<br />chlorpheniramine<br />cilostazol<br />'''[[clarithromycin]]'''<br />cocaine<br />cyclosporine<br />'''[[daclatasvir]]'''<br />'''[[dapsone]]'''<br />'''[[darunavir]]'''<br />dexamethasone<br />dextromethorphan<br />diltiazem<br />docetaxel<br />domperidone<br />'''[[elbasvir]]'''<br />eplerenone
	\|'''[[erythromycin]]'''<br />estradiol<br />'''[[etravirine]]'''<br />felodipine<br />fentanyl<br />finasteride<br />'''[[fosamprenavir]]'''<br />'''[[grazoprevir]]'''<br />haloperidol<br />hydrocortisone<br />imitanib<br />'''[[indinavir]]'''<br />irinotecan<br />lidocaine<br />lovastatin<br />'''[[maraviroc]]'''<br />midazolam<br />nateglinide<br />'''[[nelfinavir]]'''		\|'''[[erythromycin]]'''<br />estradiol<br />'''[[etravirine]]'''<br />felodipine<br />fentanyl<br />finasteride<br />'''[[fosamprenavir]]'''<br />'''[[grazoprevir]]'''<br />haloperidol<br />hydrocortisone<br />imitanib<br />'''[[indinavir]]'''<br />irinotecan<br />lidocaine<br />lovastatin<br />'''[[maraviroc]]'''<br />midazolam<br />nateglinide<br />'''[[nelfinavir]]'''<br />nifedipine<br />nisoldipine<br />nitrendipine<br />ondansetron<br />'''[[paritaprevir]]'''<br />pimozide<br />'''[[praziquantel]]'''
	nifedipine<br />nisoldipine<br />nitrendipine<br />ondansetron<br />'''[[paritaprevir]]'''<br />pimozide<br />'''[[praziquantel]]'''
	\|progesterone<br />quetiapine<br />quinidine<br />'''[[quinine]]'''<br />risperidone<br />'''[[ritonavir]]'''<br />salmeterol<br />'''[[saquinavir]]'''<br />sildenafil<br />'''[[simeprevir]]'''<br />simvastatin<br />sirolimus<br />tacrolimus<br />tadalafil<br />taxol<br />terfenadine<br />testosterone<br />'''[[tipranavir]]'''<br />trazodone<br />triazolam<br />vardenafil<br />verapamil<br />vincristine<br />zaleplon<br />ziprasidone<br />zolpidem		\|progesterone<br />quetiapine<br />quinidine<br />'''[[quinine]]'''<br />risperidone<br />'''[[ritonavir]]'''<br />salmeterol<br />'''[[saquinavir]]'''<br />sildenafil<br />'''[[simeprevir]]'''<br />simvastatin<br />sirolimus<br />tacrolimus<br />tadalafil<br />taxol<br />terfenadine<br />testosterone<br />'''[[tipranavir]]'''<br />trazodone<br />triazolam<br />vardenafil<br />verapamil<br />vincristine<br />zaleplon<br />ziprasidone<br />zolpidem
	\|-		\|-

Aidan: Made table more usable

2020-08-19T13:22:40Z

Made table more usable

Show changes

Aidan: Created page with "{| class="wikitable" ! CYP ! Inhibitors ! Inducers ! Substrates |- | CYP1A2 | amiodarone
cimetidine
'''ciprofloxacin'''
fluvoxamine
'''interferon'''
2020-05-14T22:13:25Z

Created page with "{| class="wikitable" ! CYP ! Inhibitors ! Inducers ! Substrates |- | CYP1A2 | amiodarone cimetidine '''ciprofloxacin''' fluvoxamine '''interferon'''<br..."

New page
{| class="wikitable"
! CYP
! Inhibitors
! Inducers
! Substrates
|-
| CYP1A2
| amiodarone cimetidine '''[[ciprofloxacin]]''' fluvoxamine '''[[interferon]]''' methoxsalen
| cigarette smoking marijuana smoking modafinil '''[[nafcillin]]'''
| amitriptyline caffeine clomipramine clozapine cyclobenzaprine estradiol fluvoxamine haloperidol mexiletine naproxen olanzapine ondansetron phenacetine propranolol riluzole ropivacaine tacrine theophylline tizanidine verapamil R-warfarin zileuton zolmitriptan
|-
| CYP2B6
| ticlopidine thiotepa
| phenobarbital '''[[rifampin]]'''
| bupropion cyclophosphamide '''[[efavirenz]]''' ifosfamide methadone
|-
| CYP2C8
| gemfibrozil montelukast pioglitazone quercetin rosiglitazone '''[[trimethoprim]]'''
| '''[[rifampin]]'''
| amodiaquine '''[[dasabuvir]]''' cerivastatin paclitaxel torsemide repaglinide
|-
| CYP2C9
| amiodarone fenofibrate '''[[fluconazole]]''' fluvastatin fluvoxamine '''[[isoniazid]]''' probenecid sertraline '''[[sulfamethoxazole]]''' teniposide '''[[voriconazole]]''' zafirlukast
| '''[[rifampin]]''' secorbarbital
| amitriptyline celecoxib diclofenac fluoxetine fluvastatin glipizide glyburide ibuprofen irbesartan lornoxicam losartan meloxicam nateglinide omeprazole phenytoin piroxicam rosiglitazone rosuvastatin S-warfarin tamoxifen tolbutamide torsemide
|-
| CYP2C19
| cimetidine esomeprazole felbamate fluoxetine fluvoxamine indomethacin '''[[ketoconazole]]''' lansoprazole modafinil omeprazole oxcarbazepine pantoprazole probenecid rabeprazole ticlopidine topiramate
| carbamazepine norethindrone prednisone '''[[rifampin]]'''
| carisoprodol '''[[chloramphenicol]]''' citalopram clomipramine cyclophosphamide esomeprazole hexobarbital indomethacin lansoprazole moclobemide '''[[nelfinavir]]''' nilutamide omeprazole pantoprazole phenobarbital phenytoin primidone progesterone '''[[proguanil]]''' propranolol rabeprazole teniposide '''[[voriconazole]]'''
|-
| CYP2D6
| amiodarone bupropion celecoxib chlorpheniramine chlorpromazine cimetidine citalopram clemastine clomipramine cocaine diphenhydramine doxepin doxorubicin duloxetine escitalopram fluoxetine hydroxyzine metoclopramide mibefradil midodrine moclobemide paroxetine perphenazine quinidine ranitidine '''[[ritonavir]]''' sertraline terbinafine ticlopidine
| dexamethasone '''[[rifampin]]'''
| alprenolol amitriptyline amphetamine aripiprazole atomoxetine carvedilol chlorpheniramine chlorpromazine clomipramine codeine debrisoquine desipramine dexfenfluramine dextromethorphan duloxetine encainide flecainide fluoxetine fluvoxamine haloperidol imipramine lidocaine methoxyamphetamine metoclopramide paroxetine perphenazine propafenone S-metoprolol thioridazine timolol
|-
| CYP2E1
| disulfiram
| ethanol '''[[isoniazid]]'''
| acetaminophen chlorzoxazone enflurane ethanol halothane isoflurane methoxyflurane sevoflurane
|-
| CYP3A
| amiodarone aprepitant cimetidine '''[[clarithromycin]]''' '''[[cobicistat]]''' '''[[delavirdine]]''' diltiazem '''[[elvitegravir]]''' '''[[erythromycin]]''' '''[[fluconazole]]''' fluvoxamine gestodene imatinib '''[[indinavir]]''' '''[[isavuconazonium]]''' '''[[itraconazole]]''' '''[[ketoconazole]]''' mibefradil mifepristone nefazodone '''[[nelfinavir]]''' norfluoxetine '''[[posaconazole]]''' '''[[ritonavir]]''' '''[[saquinavir]]''' verapamil '''[[voriconazole]]'''
| barbiturates carbamazepine '''[[efavirenz]]''' glucocorticoids modafinil nevirapine oxcarbazepine phenobarbital phenytoin pioglitazone '''[[rifabutin]]''' '''[[rifampin]]''' St. John’s wort
| alfentanil alprazolam amlodipine aprepitant aripiprazole '''[[artemisinin]]''' astemizole '''[[atazanavir]]''' atorvastatin '''[[bedaquiline]]''' buspirone cafergot chlorpheniramine cilostazol '''[[clarithromycin]]''' cocaine cyclosporine '''[[daclatasvir]]''' '''[[dapsone]]''' '''[[darunavir]]''' dexamethasone dextromethorphan diltiazem docetaxel domperidone '''[[elbasvir]]''' eplerenone '''[[erythromycin]]''' estradiol '''[[etravirine]]''' felodipine fentanyl finasteride '''[[fosamprenavir]]''' '''[[grazoprevir]]''' haloperidol hydrocortisone imitanib '''[[indinavir]]''' irinotecan lidocaine lovastatin '''[[maraviroc]]''' midazolam nateglinide '''[[nelfinavir]]''' nifedipine nisoldipine nitrendipine ondansetron '''[[paritaprevir]]''' pimozide '''[[praziquantel]]''' progesterone quetiapine quinidine '''[[quinine]]''' risperidone '''[[ritonavir]]''' salmeterol '''[[saquinavir]]''' sildenafil '''[[simeprevir]]''' simvastatin sirolimus tacrolimus tadalafil taxol terfenadine testosterone '''[[tipranavir]]''' trazodone triazolam vardenafil verapamil vincristine zaleplon ziprasidone zolpidem
|}

[[Category:Antimicrobials]]