Doxycycline - Revision history

Aidan at 18:56, 3 February 2026

2026-02-03T18:56:18Z

← Older revision		Revision as of 18:56, 3 February 2026
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	* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}		* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}

			=== Pharmacokinetics and Pharmacodynamics ===
	=== Distribution ===

			* Absorption is good, around 80 to 90%
	* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this[[CiteRef::jodlowski2020do]]		* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this[[CiteRef::jodlowski2020do]]
	* CSF concentration is 15-25% of serum, but with 200 mg twice daily dosing should be reliably above MIC for [[syphilis]] and [[Lyme disease]][[CiteRef::yim1985pe]][[CiteRef::dotevall1989pe]]		* CSF concentration is 15-25% of serum, but with 200 mg twice daily dosing should be reliably above MIC for [[syphilis]] and [[Lyme disease]][[CiteRef::yim1985pe]][[CiteRef::dotevall1989pe]]
			* Elimination half-life is 12 to 25 hours

	== Dosing ==		== Dosing ==

Aidan: /* Distribution */

2026-02-03T18:46:14Z

Distribution

← Older revision		Revision as of 18:46, 3 February 2026
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	* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this[[CiteRef::jodlowski2020do]]		* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this[[CiteRef::jodlowski2020do]]
			* CSF concentration is 15-25% of serum, but with 200 mg twice daily dosing should be reliably above MIC for [[syphilis]] and [[Lyme disease]][[CiteRef::yim1985pe]][[CiteRef::dotevall1989pe]]

	== Dosing ==		== Dosing ==

Aidan at 17:38, 19 September 2024

2024-09-19T17:38:00Z

← Older revision		Revision as of 17:38, 19 September 2024
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	=== Distribution ===		=== Distribution ===

	* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this~~<ref>Tomasz Jodlowski, Charles R Ashby, Sarath G Nath, Doxycycline for ESBL-E Cystitis, ''Clinical Infectious Diseases'', Volume 73, Issue 1, 1 July 2021, Pages e274–e275, https~~:~~//doi.org/10.1093/cid/ciaa1898</ref>~~		* Achieves only low concentrations in the urine, so generally not recommended for UTIs, though some debate about this[[CiteRef::jodlowski2020do]]

	== Dosing ==		== Dosing ==

Aidan at 14:57, 1 November 2023

2023-11-01T14:57:43Z

← Older revision		Revision as of 14:57, 1 November 2023
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	=== Adverse Effects ===		=== Adverse Effects ===
	* Counsel on high risk of sun sensitivity and pill esophagitis		* Counsel on high risk of sun sensitivity and pill esophagitis

			=== Pregnancy ===
	* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining		* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining
	** However, can often tolerate short courses up to 5 days without issue		** However, can often tolerate short courses up to 5 days without issue

Aidan at 14:56, 1 November 2023

2023-11-01T14:56:49Z

@@ Line 1: / Line 1: @@
 * Tetracycline antibiotic
 * Usual dosing 100 mg po BID
 * Counsel on high risk of sun sensitivity and pill esophagitis
 * Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining
 ** However, can often tolerate short courses up to 5 days without issue
 [[Category:Tetracyclines]]

Aidan at 12:49, 30 August 2022

2022-08-30T12:49:10Z

← Older revision		Revision as of 12:49, 30 August 2022
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	* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining		* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining
	** However, can often tolerate short courses up to 5 days without issue		** However, can often tolerate short courses up to 5 days without issue
			* Achieves only low concentrations in the urine, so generally not recommended for UTIs
	* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}		* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}

Aidan at 14:05, 26 August 2020

2020-08-26T14:05:11Z

← Older revision		Revision as of 14:05, 26 August 2020
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	* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}		* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}

	[[Category:~~Antibiotics~~]]		[[Category:Tetracyclines]]

Aidan at 15:19, 6 December 2019

2019-12-06T15:19:53Z

← Older revision		Revision as of 15:19, 6 December 2019
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	* Usual dosing 100 mg po BID		* Usual dosing 100 mg po BID
	* Counsel on high risk of sun sensitivity and pill esophagitis		* Counsel on high risk of sun sensitivity and pill esophagitis
			* Generally avoid using in pregnant women and children less than 8 years of age due to bone and tooth staining
			** However, can often tolerate short courses up to 5 days without issue
	* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}		* Can treat: {{#ask: [[Is treated by::doxycycline]]\|default=none}}

Aidan: Created page with "* Tetracycline antibiotic * Usual dosing 100 mg po BID * Counsel on high risk of sun sensitivity and pill esophagitis * Can treat: {{#ask: Is treated by::doxycycline|defau..."

2019-12-06T15:19:00Z

Created page with "* Tetracycline antibiotic * Usual dosing 100 mg po BID * Counsel on high risk of sun sensitivity and pill esophagitis * Can treat: {{#ask: Is treated by::doxycycline|defau..."

New page

* Tetracycline antibiotic
* Usual dosing 100 mg po BID
* Counsel on high risk of sun sensitivity and pill esophagitis
* Can treat: {{#ask: [[Is treated by::doxycycline]]|default=none}}

[[Category:Antibiotics]]