Dimorphic fungi - Revision history

Aidan at 21:09, 7 March 2024

2024-03-07T21:09:03Z

← Older revision		Revision as of 21:09, 7 March 2024
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	\|[[fluconazole]] (with [[amphotericin B]] and [[flucytosine]] induction if severe)		\|[[fluconazole]] (with [[amphotericin B]] and [[flucytosine]] induction if severe)
	\|-		\|-
	\|[[~~Histoplasma\|~~Histoplasma capsulatum]]		\|[[Histoplasma capsulatum]]
	\|worldwide, including eastern North America, Central and South America, sub-Saharan Africa, and parts of Southeast Asia		\|worldwide, including eastern North America, Central and South America, sub-Saharan Africa, and parts of Southeast Asia
	\|pulmonary infection, CNS infection		\|pulmonary infection, CNS infection

Aidan: Text replacement - " species]]" to "]]"

2022-01-25T16:47:53Z

Text replacement - " species]]" to "]]"

Aidan at 15:29, 29 October 2020

2020-10-29T15:29:52Z

Show changes

Aidan at 15:28, 29 October 2020

2020-10-29T15:28:54Z

Show changes

Aidan at 14:38, 29 October 2020

2020-10-29T14:38:57Z

← Older revision		Revision as of 14:38, 29 October 2020
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			==Background==
⚫	*~~Fungi~~ that exist in a mold form at lower temperatures in the environment, and a yeast form at higher temperatures in the host body
			===Microbiology===
		⚫	*Broad category of fungi that exist in a mold form at lower temperatures in the environment, and a yeast form at higher temperatures in the host body
	*[[Cryptococcus]] does exhibit dimorphism, though it is predominately yeast and its dimorphism is not likely related to disease		*[[Cryptococcus]] does exhibit dimorphism, though it is predominately yeast and its dimorphism is not likely related to disease
			*Often referred to as endemic fungi based on their geographic niches

	{\| class="wikitable"		{\| class="wikitable"
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	\|[[amphotericin B]] induction followed by [[itraconazole]]		\|[[amphotericin B]] induction followed by [[itraconazole]]
	\|}		\|}

	==Distribution==
			* [[Blastomyces species]], including Blastomyces dermatitidis complex ([[Blastomyces dermatitidis]] and [[Blastomyces gilchristii]]), helices, silverae, parvus
			* [[Histoplasmosis capsulatum]] (var. ''capsulatum'' and var. ''duboisii'')
			* [[Coccidiodes species]], including [[Coccidioides immitis]] and [[Coccidioides posadasii]]
			* [[Paracoccidioides species]], including [[Paracoccidioides brasiliensis]] and [[Paracoccidioides lutzii]]
			* [[Talaromyces marneffei]]
			* [[Emergomyces species]], including [[Emergomyces pasteurianus]], [[Emergomyces africanus]], [[Emergomyces orientalis]], [[Emergomyces canadensis]], [[Emergomyces europaeus]]
			* [[Sporothrix species]] complex (Sporothrix brasiliensis, Sporothrix schenckii, Sporothrix globose, Sporothrix luriei)

			===Epidemiology===

	*Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]		*Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]

	=== Histoplasmosis ===		====Histoplasmosis====

	[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]		[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]

	=== Coccidiomycosis ===		====Coccidiomycosis====

	[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]		[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]

	=== Blastomycosis ===		====Blastomycosis====

	[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]		[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]

			== Prevention ==

			=== Laboratory Safety ===

			* Many are risk group 3 and need to notify lab if suspected
			* Opening the plates outside of a BSC is one of the highest risk actions

			[[Category:Fungi]]

Aidan at 17:27, 14 September 2020

2020-09-14T17:27:07Z

← Older revision		Revision as of 17:27, 14 September 2020
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	=== Histoplasmosis ===		=== Histoplasmosis ===

	[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]		[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]

	=== Coccidiomycosis ===		=== Coccidiomycosis ===

	[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]		[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]

	=== Blastomycosis ===		=== Blastomycosis ===

	[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]		[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]

Aidan: /* Distribution */

2020-09-14T17:26:45Z

Distribution

← Older revision		Revision as of 17:26, 14 September 2020
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	*Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]		*Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]

			=== Histoplasmosis ===
	[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]		[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]

			=== Coccidiomycosis ===
	[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]		[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]

			=== Blastomycosis ===
	[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]		[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]

Aidan at 17:23, 14 September 2020

2020-09-14T17:23:49Z

← Older revision		Revision as of 17:23, 14 September 2020
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	* Fungi that exist in a mold form at lower temperatures in the environment, and a yeast form at higher temperatures in the host body		*Fungi that exist in a mold form at lower temperatures in the environment, and a yeast form at higher temperatures in the host body
	* [[Cryptococcus]] does exhibit dimorphism, though it is predominately yeast and its dimorphism is not likely related to disease		*[[Cryptococcus]] does exhibit dimorphism, though it is predominately yeast and its dimorphism is not likely related to disease

	{\| class="wikitable"		{\| class="wikitable"
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	\|[[Paracoccidioides brasiliensis]]		\|[[Paracoccidioides brasiliensis]]
	\|South America		\|South America
			\|pulmonary infection
	\|
			\|[[itraconazole]] (with [[amphotericin B]] induction if severe)
	\|
	\|-		\|-
	\|[[Sporothrix schenckii]]		\|[[Sporothrix schenckii]]
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	\|[[Talaromyces marneffei]]		\|[[Talaromyces marneffei]]
	\|Southeast Asia		\|Southeast Asia
			\|disseminated (common in advanced [[HIV]]), pulmonary infection, abdominal abscess, skin lesions, osteomyelitis
	\|
			\|[[amphotericin B]] induction followed by [[itraconazole]]
	\|
	\|}		\|}
	<br />
	==Distribution==		==Distribution==

Aidan: added table

2020-08-20T18:41:05Z

added table

← Older revision		Revision as of 18:41, 20 August 2020
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			* Fungi that exist in a mold form at lower temperatures in the environment, and a yeast form at higher temperatures in the host body
	== Species ==
			* [[Cryptococcus]] does exhibit dimorphism, though it is predominately yeast and its dimorphism is not likely related to disease
⚫	* ''[[Blastomyces ~~dermatitidis~~]]''
⚫	* ''[[Histoplasma capsulatum]]''
	* ''[[Coccidioides immitis]]'' and ''[[Coccidioides posadasii]]''
	* ''[[Cryptococcus neoformans]]'' and ''[[Cryptococcus gattii]]''
⚫	* ''[[Sporothrix schenckii]]''

			{\| class="wikitable"
⚫	== Distribution ==
			!Organism
⚫	* Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]
			!Distribution
			!Diseases
			!Treatment
			\|-
		⚫	\|[[Blastomyces species]]
			\|eastern US and Canada, with some reported in Africa
			\|pulmonary infection, verrucous skin lesions, osteomyelitis, CNS infection
			\|[[itraconazole]] (with [[amphotericin B]] induction if severe)
			\|-
			\|[[Coccidioides species]]
			\|southwestern US and parts of South and Central America
			\|pulmonary infection, verrucous skin lesions, osteomyelitis, CNS infection
			\|[[fluconazole]] (with [[amphotericin B]] and [[flucytosine]] induction if severe)
			\|-
		⚫	\|[[Histoplasma\|Histoplasma capsulatum]]
			\|worldwide, including eastern North America, Central and South America, sub-Saharan Africa, and parts of Southeast Asia
			\|pulmonary infection, CNS infection
			\|[[itraconazole]] (with [[amphotericin B]] induction if severe)
			\|-
			\|[[Paracoccidioides brasiliensis]]
			\|South America
			\|
			\|
			\|-
		⚫	\|[[Sporothrix schenckii]]
			\|essentially worldwide
			\|[[nodular lymphangitis]]
			\|[[itraconazole]]
			\|-
			\|[[Talaromyces marneffei]]
			\|Southeast Asia
			\|
			\|
			\|}
			<br />
		⚫	==Distribution==

		⚫	*Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]

	[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]		[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]

Aidan: /* Distribution */

2020-02-13T20:34:11Z

Distribution

← Older revision		Revision as of 20:34, 13 February 2020
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	== Distribution ==		== Distribution ==
	* Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]		* Endemic dimorphic fungi are widely distributed[[CiteRef::PMID32040709]]

	[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]		[[File:Histoplasmosis_map.png\|frame\|Histoplasmosis]]

	[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]		[[File:Coccidiomycosis_map.png\|frame\|Coccidiomycosis]]

	[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]		[[File:Blastomycosis_map.png\|frame\|Blastomycosis]]

← Older revision		Revision as of 16:47, 25 January 2022
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	!Treatment		!Treatment
	\|-		\|-
	\|[[Blastomyces ~~species~~]]		\|[[Blastomyces]]
	\|eastern US and Canada, with some reported in Africa		\|eastern US and Canada, with some reported in Africa
	\|pulmonary infection, verrucous skin lesions, osteomyelitis, CNS infection		\|pulmonary infection, verrucous skin lesions, osteomyelitis, CNS infection
	\|[[itraconazole]] (with [[amphotericin B]] induction if severe)		\|[[itraconazole]] (with [[amphotericin B]] induction if severe)
	\|-		\|-
	\|[[Coccidioides ~~species~~]]		\|[[Coccidioides]]
	\|southwestern US and parts of South and Central America		\|southwestern US and parts of South and Central America
	\|pulmonary infection, verrucous skin lesions, osteomyelitis, CNS infection		\|pulmonary infection, verrucous skin lesions, osteomyelitis, CNS infection
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	*Often referred to as endemic fungi based on their geographic niches		*Often referred to as endemic fungi based on their geographic niches
	*Includes the following genera and species:		*Includes the following genera and species:
	**[[Blastomyces ~~species~~]], including Blastomyces dermatitidis complex ([[Blastomyces dermatitidis]] and [[Blastomyces gilchristii]]), helices, silverae, parvus		**[[Blastomyces]], including Blastomyces dermatitidis complex ([[Blastomyces dermatitidis]] and [[Blastomyces gilchristii]]), helices, silverae, parvus
	**[[Histoplasma capsulatum]] (var. ''capsulatum'' and var. ''duboisii'')		**[[Histoplasma capsulatum]] (var. ''capsulatum'' and var. ''duboisii'')
	**[[Coccidiodes ~~species~~]], including [[Coccidioides immitis]] and [[Coccidioides posadasii]]		**[[Coccidiodes]], including [[Coccidioides immitis]] and [[Coccidioides posadasii]]
	**[[Paracoccidioides ~~species~~]], including [[Paracoccidioides brasiliensis]] and [[Paracoccidioides lutzii]]		**[[Paracoccidioides]], including [[Paracoccidioides brasiliensis]] and [[Paracoccidioides lutzii]]
	**[[Talaromyces marneffei]]		**[[Talaromyces marneffei]]
	**[[Emergomyces ~~species~~]], including [[Emergomyces pasteurianus]], [[Emergomyces africanus]], [[Emergomyces orientalis]], [[Emergomyces canadensis]], [[Emergomyces europaeus]]		**[[Emergomyces]], including [[Emergomyces pasteurianus]], [[Emergomyces africanus]], [[Emergomyces orientalis]], [[Emergomyces canadensis]], [[Emergomyces europaeus]]
	**[[Sporothrix ~~species~~]] complex (Sporothrix brasiliensis, Sporothrix schenckii, Sporothrix globose, Sporothrix luriei)		**[[Sporothrix]] complex (Sporothrix brasiliensis, Sporothrix schenckii, Sporothrix globose, Sporothrix luriei)

	===Epidemiology===		===Epidemiology===