Congenital CMV - Revision history

Aidan at 16:21, 20 September 2020

2020-09-20T16:21:56Z

← Older revision		Revision as of 16:21, 20 September 2020
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	* The focus of prevention is on [[CMV in pregnancy#Prevention\|preventing maternal disease]]		* The focus of prevention is on [[CMV in pregnancy#Prevention\|preventing maternal disease]]

	[[Category:Pediatrics]]
	[[Category:Congenital infections]]		[[Category:Congenital infections]]

2020-09-20T13:19:46Z

Diagnosis

@@ Line 63: / Line 63: @@
 |}
-* Overall, 20% of infected babies will have permanent neurological sequelae
+*Overall, 20% of infected babies will have permanent neurological sequelae
-** 50% of those symptomatic at birth and 15% of those asymptomatic
+**50% of those symptomatic at birth and 15% of those asymptomatic
 ==Clinical Manifestations==
@@ Line 91: / Line 91: @@
 ==Diagnosis==
-*In mom, IgM antibodies
+*In mom, [[CMV in pregnancy#Diagnosis|serology]]
 ==Management==
 [[Category:Pediatrics]]

2020-09-20T01:02:57Z

@@ Line 14: / Line 14: @@
 ***'''Reinfection''': 5% risk
 ***'''Reactivation''': 1% risk
 ==Clinical Manifestations==

2020-08-20T18:17:20Z

← Older revision		Revision as of 18:17, 20 August 2020
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	[[Category:Pediatrics]]		[[Category:Pediatrics]]
			[[Category:Congenital infections]]

2020-08-17T15:10:06Z

Clinical Manifestations

← Older revision		Revision as of 15:10, 17 August 2020
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	== Background ==		==Background==

	* Infection with [[cytomegalovirus]] acquired in utero		*Infection with [[cytomegalovirus]] acquired in utero
	* See also [[CMV in pregnancy]]		*See also [[CMV in pregnancy]]

	===Epidemiology===		===Epidemiology===
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	*Mother may have had asymptomatic infection		*Mother may have had asymptomatic infection
	*At birth		*At birth (10%)
	**[[Causes::Microcephaly]]		**[[Causes::Microcephaly]] (35-50%)
	**[[Causes::Periventricular calcifications]]		**[[Causes::Periventricular calcifications]]
	**[[Causes::~~Chorioretinitis~~]]		**[[Causes::Seizure]] (5-10%)
	**[[Causes::~~Sensorineural hearing loss~~]]		**[[Causes::Chorioretinitis]] (10-15%)
			**[[Causes::Sensorineural hearing loss]] (35%)
	**[[Causes::Optic nerve atrophy]]		**[[Causes::Optic nerve atrophy]]
	**[[Causes::~~Hepatosplenomegaly~~]]		**[[Causes::Petechiae]] (50-75%)
			**[[Causes::Neonatal jaundice]] (40-70%)
			**[[Causes::Hepatosplenomegaly]] (40-60%)
			**Small size for gestational age (40-50%)
			**[[Causes::Lethargy]] and [[Causes::hypotonia]] (30%)
			**Poor suck (20%)
	**[[Causes::Cytopenias]]		**[[Causes::Cytopenias]]
			**[[Causes::Hemolytic anemia]] (5-10%)
			**[[Causes::Pneumonia]] (5-10%)
	*Later		*Later
	**[[Causes::Cognitive deficits]] (7%)		**[[Causes::Cognitive deficits]] (7%)

2020-08-02T13:32:48Z

← Older revision		Revision as of 13:32, 2 August 2020
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	==~~Epidemiology~~==		== Background ==

			* Infection with [[cytomegalovirus]] acquired in utero
			* See also [[CMV in pregnancy]]

			===Epidemiology===

	*Maternal seroconversion in about 2% of pregnancies		*Maternal seroconversion in about 2% of pregnancies

2020-07-14T23:28:43Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 23:28, 14 July 2020
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	***'''Reactivation''': 1% risk		***'''Reactivation''': 1% risk

	==Clinical ~~Presentation~~==		==Clinical Manifestations==

	*Mother may have had asymptomatic infection		*Mother may have had asymptomatic infection

2020-07-14T00:34:44Z

Epidemiology

← Older revision		Revision as of 00:34, 14 July 2020
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	**Higher in childcare workers		**Higher in childcare workers
	*Risk of transmission to fetus		*Risk of transmission to fetus
			**About 1 in 200 live births in US
	**'''Primary infection''': 30% risk of congenital CMV; higher risk later in pregnancy, but worse outcomes earlier		**'''Primary infection''': 30% risk of congenital CMV; higher risk later in pregnancy, but worse outcomes earlier
	**Non-primary		**Non-primary

2020-07-14T00:33:16Z

Epidemiology

@@ Line 1: / Line 1: @@
-== Epidemiology ==
+==Epidemiology==
-== Clinical Presentation ==
+==Clinical Presentation==
 [[Category:Pediatrics]]

2020-02-08T15:07:51Z

Clinical Presentation: semantic links

← Older revision		Revision as of 15:07, 8 February 2020
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	* Mother may have had asymptomatic infection		* Mother may have had asymptomatic infection
	* At birth		* At birth
	** Microcephaly		** [[Causes::Microcephaly]]
	** Periventricular calcifications		** [[Causes::Periventricular calcifications]]
	** Chorioretinitis		** [[Causes::Chorioretinitis]]
	** Sensorineural hearing loss		** [[Causes::Sensorineural hearing loss]]
	** Optic nerve atrophy		** [[Causes::Optic nerve atrophy]]
	** Hepatosplenomegaly		** [[Causes::Hepatosplenomegaly]]
			** [[Causes::Cytopenias]]
	** Cytopenia
	* Later		* Later
	** Cognitive deficits (7%)		** [[Causes::Cognitive deficits]] (7%)
	** Sensorineural hearing loss (20%)		** [[Causes::Sensorineural hearing loss]] (20%)

	== Diagnosis ==		== Diagnosis ==