Complement deficiency - Revision history

Aidan at 15:31, 9 February 2026

2026-02-09T15:31:53Z

← Older revision		Revision as of 15:31, 9 February 2026
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	\|Early (C1, C2, and C4)		\|Early (C1, C2, and C4)
	\|Encapsulated bacterial infections like [[Streptococcus pneumoniae]] and [[Haemophilus influenzae]] type b. Higher risk of autoimmune diseases, particularly [[systemic lupus erythematosus]])		\|Encapsulated bacterial infections like [[Streptococcus pneumoniae]] and [[Haemophilus influenzae]] type b. Higher risk of autoimmune diseases, particularly [[systemic lupus erythematosus]].
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	\|Early (C3)		\|Early (C3)

Aidan: /* Clinical Manifestations */

2023-02-24T17:07:04Z

Clinical Manifestations

← Older revision		Revision as of 17:07, 24 February 2023
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	\|Early (C3)		\|Early (C3)
	\|~~Ssevere~~ recurrent pyogenic infections early in life		\|Severe recurrent pyogenic infections early in life
	\|-		\|-
	\|Late (C5-C9)		\|Late (C5-C9)

Aidan: Created page with "== Background == * Group of primary or acquired immunodeficiencies affecting the complement system within the innate humoural immune system * Usually autosomal recessive genetic diseases * Commonly defined as early (C1-C4) or late (C5-C9) == Clinical Manifestations == {| class="wikitable" !Deficiency ! |- |Early (C1, C2, and C4) |Encapsulated bacterial infections like Streptococcus pneumoniae and Haemophilus influenzae type b. Higher risk..."

2023-02-24T16:55:20Z

Created page with "== Background == * Group of primary or acquired immunodeficiencies affecting the complement system within the innate humoural immune system * Usually autosomal recessive genetic diseases * Commonly defined as early (C1-C4) or late (C5-C9) == Clinical Manifestations == {| class="wikitable" !Deficiency ! |- |Early (C1, C2, and C4) |Encapsulated bacterial infections like Streptococcus pneumoniae and Haemophilus influenzae type b. Higher risk..."

New page

== Background ==

* Group of primary or acquired [[Immunodeficiency|immunodeficiencies]] affecting the complement system within the innate humoural immune system
* Usually autosomal recessive genetic diseases
* Commonly defined as early (C1-C4) or late (C5-C9)

== Clinical Manifestations ==
{| class="wikitable"
!Deficiency
!
|-
|Early (C1, C2, and C4)
|Encapsulated bacterial infections like [[Streptococcus pneumoniae]] and [[Haemophilus influenzae]] type b. Higher risk of autoimmune diseases, particularly [[systemic lupus erythematosus]])
|-
|Early (C3)
|Ssevere recurrent pyogenic infections early in life
|-
|Late (C5-C9)
|Recurrent [[Neisseria]] infections
|-
|Alternative (properdin)
|Recurrent [[Neisseria]] infections
|-
|Mannan-binding lectin
|Increase frequency of pyogenic infections, particularly in young children
|}
[[Category:Immunodeficiencies]]