https://idwiki.org/index.php?action=history&feed=atom&title=Common_variable_immune_deficiency 2026-04-26T03:07:31Z Revision history for this page on the wiki MediaWiki 1.43.8 https://idwiki.org/index.php?title=Common_variable_immune_deficiency&diff=11321&oldid=prev 2025-10-06T20:32:10Z

<p>Redirected page to <a href="/Common_variable_immunodeficiency" title="Common variable immunodeficiency">Common variable immunodeficiency</a></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:32, 6 October 2025</td> </tr><tr> <td colspan="2" class="diff-lineno">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td> </tr> <tr> <td colspan="2" class="diff-empty diff-side-deleted"></td> <td class="diff-marker"><a class="mw-diff-movedpara-right" title="Paragraph was moved. Click to jump to old location." href="#movedpara_2_13_lhs">&#x26AB;</a></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><a name="movedpara_0_0_rhs"></a><ins style="font-weight: bold; text-decoration: none;">#REDIRECT</ins> <ins style="font-weight: bold; text-decoration: none;">[[Common</ins> <ins style="font-weight: bold; text-decoration: none;">variable</ins> immunodeficiency<ins style="font-weight: bold; text-decoration: none;">]]</ins></div></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== Clinical Manifestations ==</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><br /></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Recurrent sinopulmonary infections</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Chronic diarrhea, including IBD-like disease</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Can have concurrent autoimmune disease, including [[ITP]], [[AIHA]], [[rheumatoid arthritis]], [[pernicious anemia]], [[autoimmune thyroiditis]], and [[vitiligo]]</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Can have signs and symptoms of allergic rhinitis and asthma</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Can have splenomegaly and lymphadenopathy</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Increased risk of [[non-Hodgkin lymphoma]]</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><br /></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== Differential Diagnosis ==</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><br /></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Primary hypogammaglobulinemia</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** IgG subclass deficiency</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Hyperimmunoglobulin M syndrome</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker"><a class="mw-diff-movedpara-left" title="Paragraph was moved. Click to jump to new location." href="#movedpara_0_0_rhs">&#x26AB;</a></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><a name="movedpara_2_13_lhs"></a><del style="font-weight: bold; text-decoration: none;">**</del> <del style="font-weight: bold; text-decoration: none;">Other</del> <del style="font-weight: bold; text-decoration: none;">combined</del> immunodeficiency</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Secondary hypogammaglobulinemia</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Drugs, including [[rituximab]], [[CAR-T]], [[BiTE]], long-term [[corticosteroids]], certain antiseizure medications, cytotoxic chemotherapy</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Malignancy, including [[CLL]], [[lymphoma]], [[multiple myeloma]], and [[Waldenström macroglobulinemia]]</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Thymoma with hypogammaglobulinemia ([[Good syndrome]])</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><br /></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>== Diagnosis ==</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><br /></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* Over the age of 4 years</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* All of the following:</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Low IgA and/or IgM</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Poor or absent response to immunization</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <tr> <td class="diff-marker" data-marker="−"></td> <td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>** Absence of other immunodeficiency</div></td> <td colspan="2" class="diff-empty diff-side-added"></td> </tr> <!-- diff cache key site7_mediawiki:diff:1.41:old-11319:rev-11321:wikidiff2=table:1.13.0:bc2a06be --> </table>

Aidan https://idwiki.org/index.php?title=Common_variable_immune_deficiency&diff=11319&oldid=prev 2025-10-06T20:30:10Z

<p>Created page with &quot;== Clinical Manifestations == * Recurrent sinopulmonary infections * Chronic diarrhea, including IBD-like disease * Can have concurrent autoimmune disease, including <a href="/index.php?title=ITP&amp;action=edit&amp;redlink=1" class="new" title="ITP (page does not exist)">ITP</a>, <a href="/index.php?title=AIHA&amp;action=edit&amp;redlink=1" class="new" title="AIHA (page does not exist)">AIHA</a>, <a href="/Rheumatoid_arthritis" title="Rheumatoid arthritis">rheumatoid arthritis</a>, <a href="/index.php?title=Pernicious_anemia&amp;action=edit&amp;redlink=1" class="new" title="Pernicious anemia (page does not exist)">pernicious anemia</a>, <a href="/index.php?title=Autoimmune_thyroiditis&amp;action=edit&amp;redlink=1" class="new" title="Autoimmune thyroiditis (page does not exist)">autoimmune thyroiditis</a>, and <a href="/index.php?title=Vitiligo&amp;action=edit&amp;redlink=1" class="new" title="Vitiligo (page does not exist)">vitiligo</a> * Can have signs and symptoms of allergic rhinitis and asthma * Can have splenomegaly and lymphadenopathy * Increased risk of <a href="/index.php?title=Non-Hodgkin_lymphoma&amp;action=edit&amp;redlink=1" class="new" title="Non-Hodgkin lymphoma (page does not exist)">non-Hodgkin lymphoma</a> == Differential Diagnosis == * Primary hyp...&quot;</p> <p><b>New page</b></p><div>== Clinical Manifestations ==<br /> <br /> * Recurrent sinopulmonary infections<br /> * Chronic diarrhea, including IBD-like disease<br /> * Can have concurrent autoimmune disease, including [[ITP]], [[AIHA]], [[rheumatoid arthritis]], [[pernicious anemia]], [[autoimmune thyroiditis]], and [[vitiligo]]<br /> * Can have signs and symptoms of allergic rhinitis and asthma<br /> * Can have splenomegaly and lymphadenopathy<br /> * Increased risk of [[non-Hodgkin lymphoma]]<br /> <br /> == Differential Diagnosis ==<br /> <br /> * Primary hypogammaglobulinemia<br /> ** IgG subclass deficiency<br /> ** Hyperimmunoglobulin M syndrome<br /> ** Other combined immunodeficiency<br /> * Secondary hypogammaglobulinemia<br /> ** Drugs, including [[rituximab]], [[CAR-T]], [[BiTE]], long-term [[corticosteroids]], certain antiseizure medications, cytotoxic chemotherapy<br /> ** Malignancy, including [[CLL]], [[lymphoma]], [[multiple myeloma]], and [[Waldenström macroglobulinemia]]<br /> ** Thymoma with hypogammaglobulinemia ([[Good syndrome]])<br /> <br /> == Diagnosis ==<br /> <br /> * Over the age of 4 years<br /> * All of the following:<br /> ** Low IgA and/or IgM<br /> ** Poor or absent response to immunization<br /> ** Absence of other immunodeficiency</div>

Aidan