Bartonella henselae - Revision history

Aidan: /* Other Syndromes */

2025-07-23T18:21:11Z

Other Syndromes

← Older revision		Revision as of 18:21, 23 July 2025
Line 41:		Line 41:
	**Culture-negative [[Causes::endocarditis]] in patients with existing valve abnormalities		**Culture-negative [[Causes::endocarditis]] in patients with existing valve abnormalities
	**Chronic endocarditis, with [[Causes::vasculitis]] and [[Causes::glomerulonephritis]]		**Chronic endocarditis, with [[Causes::vasculitis]] and [[Causes::glomerulonephritis]]
	*Disseminated disease is possible in immunocompromised patients, including bacteremia, disseminated skin lesions, and hepatosplenic lesions		*Disseminated disease is possible in immunocompromised patients, including bacteremia, disseminated skin lesions, and hepatosplenic lesions (see also [[bacillary angiomatosis]])

	==Diagnosis==		==Diagnosis==

Aidan at 18:18, 23 July 2025

2025-07-23T18:18:39Z

← Older revision		Revision as of 18:18, 23 July 2025
Line 1:		Line 1:
	==Background==		==Background==

			*Species of [[Stain::Gram-negative]] intracellular bacteria within the genus [[Genus::Bartonella]]
	*Causes '''cat-scratch disease'''		*Causes '''cat-scratch disease'''

Aidan: /* Diagnosis */

2024-10-17T15:23:13Z

Diagnosis

← Older revision		Revision as of 15:23, 17 October 2024
Line 44:		Line 44:
	==Diagnosis==		==Diagnosis==

	*Histopathology of node aspirate shows nonspecific inflammation, with granulomas and stellate ~~ncerosis~~		*Histopathology of node aspirate shows nonspecific inflammation, with granulomas and stellate necrosis
	**Microabscesses are classic finding		**Microabscesses are classic finding
	**Bacilli may be seen with Warthin-Starry staining		**Bacilli may be seen with Warthin-Starry staining

Aidan: /* Cat Scratch Disease */

2022-10-04T01:14:43Z

Cat Scratch Disease

← Older revision		Revision as of 01:14, 4 October 2022
Line 16:		Line 16:
	*Typical cat-scratch disease is a self-limited febrile illness with [[Causes::regional lymphadenopathy]]		*Typical cat-scratch disease is a self-limited febrile illness with [[Causes::regional lymphadenopathy]]
	**Following an incubation period of [[Usual incubation period::3 to 10 days]], and initial pustule develops at site of inoculation which may last for up to 3 weeks		**Following an incubation period of [[Usual incubation period::3 to 10 days]], and initial pustule develops at site of inoculation which may last for up to 3 weeks
			**Usually a history of cat exposure (adult or kitten), but 5-10% have no known exposure
	**This is followed in 1 to 7 weeks by ipsilateral [[Causes::lymphadenopathy]] (usually the head or neck)		**This is followed in 1 to 7 weeks by ipsilateral [[Causes::lymphadenopathy]] (usually the head or neck)
	***May involve one or more lymph nodes		***May involve one or more lymph nodes
Line 22:		Line 23:
	**There may be a concurrent low-grade [[Causes::fever]] for several days, with [[Causes::malaise]] or [[Causes::fatigue]]		**There may be a concurrent low-grade [[Causes::fever]] for several days, with [[Causes::malaise]] or [[Causes::fatigue]]
	**May have [[Causes::headache,]] sore throat, transient rash, or, rarely, [[Causes::erythema nodosum]]		**May have [[Causes::headache,]] sore throat, transient rash, or, rarely, [[Causes::erythema nodosum]]
	**May have mild leukocytosis (neutrophils or eosinophils)		**May have mild leukocytosis (neutrophils or eosinophils), mildly elevated C-reactive protein or ESR
	*CSD may be complicated by [[Causes::encephalopathy]] in 2 to 4% of cases		*CSD may be complicated by [[Causes::encephalopathy]] in 2 to 4% of cases
	**Headache is common, and they may develop seizures and neurologic deficits		**Headache is common, and they may develop seizures and neurologic deficits

Aidan: /* Management */

2020-09-17T01:14:20Z

Management

Show changes

Aidan: /* Clinical Manifestations */

2020-08-05T13:55:53Z

Clinical Manifestations

← Older revision		Revision as of 13:55, 5 August 2020
Line 10:		Line 10:
	==Clinical Manifestations==		==Clinical Manifestations==
	* Typical cat-scratch disease is a self-limited febrile illness with [[Causes::regional lymphadenopathy]]		* Typical cat-scratch disease is a self-limited febrile illness with [[Causes::regional lymphadenopathy]]
	** Following an incubation period of 3 to 10 days, and initial pustule develops at site of inoculation which may last for up to 3 weeks		** Following an incubation period of [[Usual incubation period::3 to 10 days]], and initial pustule develops at site of inoculation which may last for up to 3 weeks
	** This is followed in 1 to 7 weeks by ipsilateral [[Causes::lymphadenopathy]] (usually the head or neck)		** This is followed in 1 to 7 weeks by ipsilateral [[Causes::lymphadenopathy]] (usually the head or neck)
	*** May involve one or more lymph nodes		*** May involve one or more lymph nodes

Aidan: Text replacement - "Has vector::" to "Vector::"

2020-08-02T12:19:37Z

Text replacement - "Has vector::" to "Vector::"

← Older revision		Revision as of 12:19, 2 August 2020
Line 6:		Line 6:
	* Main reservoir is cats, and especially kittens		* Main reservoir is cats, and especially kittens
	* Infections are more common in children, likely due to increased exposure to kittens		* Infections are more common in children, likely due to increased exposure to kittens
	* Transmitted to humans by inoculation of cat flea (''[[~~Has vector~~::Ctenocephalides felis]]'') feces into a cat scratch or bite		* Transmitted to humans by inoculation of cat flea (''[[Vector::Ctenocephalides felis]]'') feces into a cat scratch or bite

	==Clinical Manifestations==		==Clinical Manifestations==

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-15T12:14:33Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

← Older revision		Revision as of 12:14, 15 July 2020
Line 8:		Line 8:
	* Transmitted to humans by inoculation of cat flea (''[[Has vector::Ctenocephalides felis]]'') feces into a cat scratch or bite		* Transmitted to humans by inoculation of cat flea (''[[Has vector::Ctenocephalides felis]]'') feces into a cat scratch or bite

	==Clinical ~~Presentation~~==		==Clinical Manifestations==
	* Typical cat-scratch disease is a self-limited febrile illness with [[Causes::regional lymphadenopathy]]		* Typical cat-scratch disease is a self-limited febrile illness with [[Causes::regional lymphadenopathy]]
	** Following an incubation period of 3 to 10 days, and initial pustule develops at site of inoculation which may last for up to 3 weeks		** Following an incubation period of 3 to 10 days, and initial pustule develops at site of inoculation which may last for up to 3 weeks

Aidan at 15:17, 20 June 2020

2020-06-20T15:17:59Z

← Older revision		Revision as of 15:17, 20 June 2020
Line 6:		Line 6:
	* Main reservoir is cats, and especially kittens		* Main reservoir is cats, and especially kittens
	* Infections are more common in children, likely due to increased exposure to kittens		* Infections are more common in children, likely due to increased exposure to kittens
	* Transmitted to humans by inoculation of cat flea (''[[Ctenocephalides felis]]'') feces into a cat scratch or bite		* Transmitted to humans by inoculation of cat flea (''[[Has vector::Ctenocephalides felis]]'') feces into a cat scratch or bite

	==Clinical Presentation==		==Clinical Presentation==

Aidan: /* Management */ added endocarditis

2020-05-16T01:25:00Z

Management: added endocarditis

← Older revision		Revision as of 01:25, 16 May 2020
Line 52:		Line 52:
	* First-line: [[Is treated by::azithromycin]] 500 mg po on day 1 followed by 250 mg po daily for 4 more days (10 mg/kg and 5 mg/kg for children)		* First-line: [[Is treated by::azithromycin]] 500 mg po on day 1 followed by 250 mg po daily for 4 more days (10 mg/kg and 5 mg/kg for children)
	* Hepatosplenic CSD in children may respond to combination [[Is treated by::azithromycin]] ± [[Is treated by::rifampin]] for 14 days		* Hepatosplenic CSD in children may respond to combination [[Is treated by::azithromycin]] ± [[Is treated by::rifampin]] for 14 days

			===Endocarditis===
			* [[Is treated by::Doxycycline]] and [[Is treated by::gentamicin]] for 14 days followed by [[doxycycline]] alone for three months, or until 6 weeks after valve replacement (if done)

	{{DISPLAYTITLE:''Bartonella henselae''}}		{{DISPLAYTITLE:''Bartonella henselae''}}