Bartonella bacilliformis - Revision history

Aidan: /* Clinical Manifestations */

2020-08-05T13:47:36Z

Clinical Manifestations

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	==Clinical Manifestations==		==Clinical Manifestations==
	* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')		* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')
	* The acute phase starts after an incubation period of 3 to 12 weeks, and is characterized by fever, malaise, and a hemolytic anemia		* The acute phase starts after an incubation period of [[Usual incubation period::3 to 12 weeks]], and is characterized by fever, malaise, and a hemolytic anemia
	** May only last a week and not present for medical care		** May only last a week and not present for medical care
	** More severe disease can include high fever, chills, diaphoresis, anorexia, prostration, headache, and altered mental status		** More severe disease can include high fever, chills, diaphoresis, anorexia, prostration, headache, and altered mental status

Aidan: Text replacement - "Has vector::" to "Vector::"

2020-08-02T12:15:06Z

Text replacement - "Has vector::" to "Vector::"

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	===Epidemiology===		===Epidemiology===
	* Range is essentially restricted to the Andean mountains in Peru, Ecuador, and Colombia		* Range is essentially restricted to the Andean mountains in Peru, Ecuador, and Colombia
	* Transmitted by ''[[~~Has vector~~::Lutzomyia]]'' sand flies		* Transmitted by ''[[Vector::Lutzomyia]]'' sand flies
	* Humans are primary reservoir		* Humans are primary reservoir

Aidan: Text replacement - "Clinical Presentation" to "Clinical Manifestations"

2020-07-18T14:38:02Z

Text replacement - "Clinical Presentation" to "Clinical Manifestations"

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	* Humans are primary reservoir		* Humans are primary reservoir

	==Clinical ~~Presentation~~==		==Clinical Manifestations==
	* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')		* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')
	* The acute phase starts after an incubation period of 3 to 12 weeks, and is characterized by fever, malaise, and a hemolytic anemia		* The acute phase starts after an incubation period of 3 to 12 weeks, and is characterized by fever, malaise, and a hemolytic anemia

Aidan: /* Clinical Presentation */

2020-05-16T00:46:15Z

Clinical Presentation

← Older revision		Revision as of 00:46, 16 May 2020
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	==Clinical Presentation==		==Clinical Presentation==
	* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')		* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')
	* The acute phase is characterized by fever, malaise, and a hemolytic anemia		* The acute phase starts after an incubation period of 3 to 12 weeks, and is characterized by fever, malaise, and a hemolytic anemia
			** May only last a week and not present for medical care
⚫	* The late phase is characterized by nodular skin lesions
			** More severe disease can include high fever, chills, diaphoresis, anorexia, prostration, headache, and altered mental status
			** The anemia can be profound in severe disease
			** May be accompanied by severe myalgias and arthralgias, abdominal pain, emesis, jaundice, lymphadenopathy, thrombocytopenia, seizures, delirium, meningoencephalitis, obtundation, dyspnea, hepatic dysfunction, and angina, likely secondary to anemia and microvascular thrombosis
			** Severe disease has high mortality if untreated, but decreases to 10% if treated
		⚫	* The late phase occurs weeks to months after the acute phase, and is characterized by disseminated nodular skin lesions
			** Crops of lesions proceed from miliary, to nodular, to mulaire lesions
			** Mulaire lesions are superficial vascular bulbous lesions that can bleed and ulcerate
			** Lesions can also be internal
			** Lesions can come and go, with recurrences, over weeks to months

	==Diagnosis==		==Diagnosis==

Aidan at 00:32, 16 May 2020

2020-05-16T00:32:23Z

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	==Management==		==Management==

			{{DISPLAYTITLE:''Bartonella bacilliformis''}}

Aidan: initial creation with brief epidemiology and presentation

2020-05-16T00:32:06Z

initial creation with brief epidemiology and presentation

New page

==Background==
===Epidemiology===
* Range is essentially restricted to the Andean mountains in Peru, Ecuador, and Colombia
* Transmitted by ''[[Has vector::Lutzomyia]]'' sand flies
* Humans are primary reservoir

==Clinical Presentation==
* Traditionally presents as a biphasic illness with an acute phase ('''Oroya fever''') and a late phase ('''verruga peruana''')
* The acute phase is characterized by fever, malaise, and a hemolytic anemia
* The late phase is characterized by nodular skin lesions

==Diagnosis==
* During acute phase, may see intraerythrocytic bacteria on blood film

==Management==