Bacillus anthracis - Revision history

Aidan: Text replacement - "[[Hemolysis::" to "[[Hemolysis pattern::"

2026-01-27T15:19:48Z

Text replacement - "[[Hemolysis::" to "[[Hemolysis pattern::"

← Older revision		Revision as of 15:19, 27 January 2026
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	===Microbiology===		===Microbiology===

	*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]		*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus]] by being [[Motility::non-motile]] and [[Hemolysis pattern::non-hemolytic]]
	*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance		*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance
	*The main toxin has subunits A and B		*The main toxin has subunits A and B

Aidan at 17:17, 19 September 2024

2024-09-19T17:17:37Z

← Older revision		Revision as of 17:17, 19 September 2024
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	* Meningitis: [[ciprofloxacin]] plus [[meropenem]] plus [[linezolid]]		* Meningitis: [[ciprofloxacin]] plus [[meropenem]] plus [[linezolid]]
	** Duration 2-3 weeks, then prophylaxis to complete 60 days		** Duration 2-3 weeks, then prophylaxis to complete 60 days
			* Almost universally susceptible to [[ciprofloxacin]] and [[doxycycline]][[CiteRef::maxson2022sy]]
	* Almost universally susceptible to [[ciprofloxacin]] and [[doxycycline]]<ref>Tucker Maxson, Thiphasone Kongphet-Tran, Thitipong Mongkolrattanothai, Tatiana Travis, Katherine Hendricks, Corinne Parker, Heather P McLaughlin, Julia Bugrysheva, Frank Ambrosio, Pierre Michel, Blake Cherney, Christine Lascols, David Sue, Systematic Review of In Vitro Antimicrobial Susceptibility Testing for ''Bacillus anthracis'', 1947–2019, ''Clinical Infectious Diseases'', Volume 75, Issue Supplement_3, 15 October 2022, Pages S373–S378, <nowiki>https://doi.org/10.1093/cid/ciac520</nowiki></ref>
	* Generally susceptible to [[penicillin]], though should wait for susceptibility results before using		* Generally susceptible to [[penicillin]], though should wait for susceptibility results before using
	* Often resistant to extended-spectrum β-lactams such as [[ceftriaxone]] and [[ceftazidime]], as well as [[aztreonam]] and [[TMP-SMX]]		* Often resistant to extended-spectrum β-lactams such as [[ceftriaxone]] and [[ceftazidime]], as well as [[aztreonam]] and [[TMP-SMX]]

Aidan at 02:43, 23 October 2022

2022-10-23T02:43:43Z

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 *Infects oropharynx or abdomen
 *Causes sepsis{{DISPLAYTITLE:''Bacillus anthracis''}}
 [[Category:Gram-positive bacilli]]

Aidan: Text replacement - " species]]" to "]]"

2022-02-09T08:37:05Z

Text replacement - " species]]" to "]]"

← Older revision		Revision as of 08:37, 9 February 2022
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	===Microbiology===		===Microbiology===

	*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus ~~species~~]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]		*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]
	*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance		*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance
	*The main toxin has subunits A and B		*The main toxin has subunits A and B

Aidan at 18:07, 7 October 2021

2021-10-07T18:07:48Z

← Older revision		Revision as of 18:07, 7 October 2021
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	*Causes '''anthrax'''

	==Background==		==Background==

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	*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus species]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]		*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus species]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]
	*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance		*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance
			*The main toxin has subunits A and B
			**A subunit may be either EF (edema factor) or LF (lethal factor)
			**B subunit is the protective antigen, against which antibodies react
			*Lives in soil
			*Wild and farm animals that have contact with contaminated soil is a common exposure, including to wool and animal hides
			*Can also be acquired by inhalation of spores

	==Clinical Manifestations==		==Clinical Manifestations==

	===Cutaneous ~~anthrax~~===		===Cutaneous Anthrax===

	*Caused by inoculation of spores into soft tissue		*Caused by inoculation of spores into soft tissue
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	*May progress to sepsis		*May progress to sepsis

	===Pulmonary ~~anthrax~~===		===Pulmonary Anthrax===

	*Caused by inhalation of spores		*Caused by inhalation of spores
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	*Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death		*Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death

	===Gastrointestinal ~~anthrax~~===		===Gastrointestinal Anthrax===

	*Caused by ingestion of spores		*Caused by ingestion of spores

Aidan: Text replacement - "[[Cellular shape::" to "[[Shape::"

2020-10-08T14:25:45Z

Text replacement - "[[Cellular shape::" to "[[Shape::"

← Older revision		Revision as of 14:25, 8 October 2020
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	===Microbiology===		===Microbiology===

	*[[Stain::Gram-positive]] [[~~Cellular shape~~::bacillus]] that is distinguished from other [[Bacillus species]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]		*[[Stain::Gram-positive]] [[Shape::bacillus]] that is distinguished from other [[Bacillus species]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]
	*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance		*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance

Aidan: /* Clinical Manifestations */

2020-08-05T13:43:44Z

Clinical Manifestations

← Older revision		Revision as of 13:43, 5 August 2020
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	*Caused by inoculation of spores into soft tissue		*Caused by inoculation of spores into soft tissue
	*Incubation period of 2 to 5 days		*Incubation period of [[Usual incubation period::2 to 5 days]]
	*Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar		*Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar
	*May progress to sepsis		*May progress to sepsis
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	*Infects oropharynx or abdomen		*Infects oropharynx or abdomen
	*Causes sepsis{{DISPLAYTITLE:''Bacillus anthracis''}}		*Causes sepsis{{DISPLAYTITLE:''Bacillus anthracis''}}

	[[Category:Gram-positive bacilli]]		[[Category:Gram-positive bacilli]]

Aidan: /* Microbiology */

2020-07-28T00:49:57Z

Microbiology

← Older revision		Revision as of 00:49, 28 July 2020
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	*Causes '''anthrax'''		*Causes '''anthrax'''

	== Background ==		==Background==

	=== Microbiology ===		===Microbiology===

	*[[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is distinguished from other [[Bacillus species]] by being non-motile and non-hemolytic		*[[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is distinguished from other [[Bacillus species]] by being [[Motility::non-motile]] and [[Hemolysis::non-hemolytic]]
			*Colonies are gray, flat, and may have a "Medusa head" or "comet" appearance

	== Clinical Manifestations ==		==Clinical Manifestations==

	=== Cutaneous anthrax ===		===Cutaneous anthrax===

	* Caused by inoculation of spores into soft tissue		*Caused by inoculation of spores into soft tissue
	* Incubation period of 2 to 5 days		*Incubation period of 2 to 5 days
	* Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar		*Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar
	* May progress to sepsis		*May progress to sepsis

	=== Pulmonary anthrax ===		===Pulmonary anthrax===

	* Caused by inhalation of spores		*Caused by inhalation of spores
	* Also known as woolsorter's disease		*Also known as woolsorter's disease
	* Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death		*Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death

	=== Gastrointestinal anthrax ===		===Gastrointestinal anthrax===

	* Caused by ingestion of spores		*Caused by ingestion of spores
	* Infects oropharynx or abdomen		*Infects oropharynx or abdomen
	* Causes sepsis		*Causes sepsis{{DISPLAYTITLE:''Bacillus anthracis''}}

	<br />{{DISPLAYTITLE:''Bacillus anthracis''}}
	[[Category:Gram-positive bacilli]]		[[Category:Gram-positive bacilli]]

Aidan at 00:48, 28 July 2020

2020-07-28T00:48:32Z

← Older revision		Revision as of 00:48, 28 July 2020
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	* Causes '''anthrax'''		*Causes '''anthrax'''
⚫	* [[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is non-motile and non-hemolytic

			== Background ==
⚫	{{DISPLAYTITLE:''Bacillus anthracis''}}

			=== Microbiology ===

		⚫	*[[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is distinguished from other [[Bacillus species]] by being non-motile and non-hemolytic

			== Clinical Manifestations ==

			=== Cutaneous anthrax ===

			* Caused by inoculation of spores into soft tissue
			* Incubation period of 2 to 5 days
			* Lesion develops at site of inoculation, starting as erythemaous papule, then ulceration, then eschar
			* May progress to sepsis

			=== Pulmonary anthrax ===

			* Caused by inhalation of spores
			* Also known as woolsorter's disease
			* Start with malaise, fever, and nonproductive cough, followed by respiratory distress, severe pulmonary edema, and death

			=== Gastrointestinal anthrax ===

			* Caused by ingestion of spores
			* Infects oropharynx or abdomen
			* Causes sepsis

		⚫	<br />{{DISPLAYTITLE:''Bacillus anthracis''}}
	[[Category:Gram-positive bacilli]]		[[Category:Gram-positive bacilli]]

Aidan at 00:44, 28 July 2020

2020-07-28T00:44:22Z

← Older revision		Revision as of 00:44, 28 July 2020
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	* Causes '''anthrax'''		* Causes '''anthrax'''
	* Stain::Gram-positive]] [[Cellular shape::bacillus]] that is non-motile and non-hemolytic		* [[Stain::Gram-positive]] [[Cellular shape::bacillus]] that is non-motile and non-hemolytic

	{{DISPLAYTITLE:''Bacillus anthracis''}}		{{DISPLAYTITLE:''Bacillus anthracis''}}