https://idwiki.org/index.php?action=history&feed=atom&title=Autosomal_dominant_polycystic_kidney_disease 2026-05-19T09:11:12Z Revision history for this page on the wiki MediaWiki 1.43.8 https://idwiki.org/index.php?title=Autosomal_dominant_polycystic_kidney_disease&diff=4106&oldid=prev 2020-07-04T01:17:24Z

<p>Imported from text file</p> <p><b>New page</b></p><div>== Classification ==<br /> <br /> * Autosomal dominant PKD (ADPKD): presents in adulthood; family history<br /> * Autosomal recessive PKD (ARPKD): presents in childhood; severe<br /> <br /> == Clinical Presenation ==<br /> <br /> * Flank pain from renal hemorrhage, calculi, or UTI<br /> * Hypertension and hematuria<br /> * CKD, usually starting in the 4th decade<br /> ** Risk factors for progressive CKD include hypertension, early onset of symptoms, male gender, and increased renal size<br /> <br /> === Extrarenal complications ===<br /> <br /> * &#039;&#039;&#039;Cerebral aneurysms (5-20%),&#039;&#039;&#039; hepatic and pancreatic cysts, cardiac valve disease, colonic diverticula, abdominal wall and inguinal hernias and seminal vesicle cysts<br /> <br /> == Management ==<br /> <br /> === CKD ===<br /> <br /> * Manage risk factors, especially hypertension<br /> * ACEi/ARB for hypertension and to slow CKD (especially if proteinuric)<br /> * Eventually needs hemodialysis or renal transplant<br /> <br /> === Extrarenal Complications ===<br /> <br /> * Needs screening for cerebral aneurysms<br /> <br /> [[Category:Nephrology]]</div>

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