Aseptic meningitis - Revision history

Aidan: /* Differential Diagnosis */

2025-11-10T17:31:41Z

Differential Diagnosis

← Older revision		Revision as of 17:31, 10 November 2025
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	***[[Herpes simplex virus]] (especially HSV-2, as primary infection)		***[[Herpes simplex virus]] (especially HSV-2, as primary infection)
	***[[Varicella]]		***[[Varicella]]
	***[[Mumps]] (encephalitis), measles (acute encephalitis)		***[[Mumps]] (encephalitis), [[Measles virus\|measles]] (acute encephalitis)
	***[[Arboviruses]]		***[[Arboviruses]]
	***[[Lymphocytic choriomeningitis virus]] (LCMV)		***[[Lymphocytic choriomeningitis virus]] (LCMV)

Aidan at 14:08, 25 July 2023

2023-07-25T14:08:24Z

← Older revision		Revision as of 14:08, 25 July 2023
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	==Differential Diagnosis==		==Differential Diagnosis==

			*See also causes of [[CSF pleocytosis]]
	*Infectious		*Infectious
	**Viral		**Viral

Aidan: /* Differential Diagnosis */

2023-05-02T16:28:39Z

Differential Diagnosis

← Older revision		Revision as of 16:28, 2 May 2023
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	****CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33		****CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33
	***[[Parechovirus]], especially in very young children and immunocompromised hosts		***[[Parechovirus]], especially in very young children and immunocompromised hosts
	***[[Herpes]] (especially HSV-2, as primary infection)		***[[Herpes simplex virus]] (especially HSV-2, as primary infection)
	***[[Varicella]]		***[[Varicella]]
	***[[Mumps]] (encephalitis), measles (acute encephalitis)		***[[Mumps]] (encephalitis), measles (acute encephalitis)

Aidan: Text replacement - " species]]" to "]]"

2022-02-02T19:53:59Z

Text replacement - " species]]" to "]]"

← Older revision		Revision as of 19:53, 2 February 2022
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	***[[Leptospirosis]]		***[[Leptospirosis]]
	***[[Lyme disease]]		***[[Lyme disease]]
	***[[Rickettsia ~~species~~]] (before onset of fever)		***[[Rickettsia]] (before onset of fever)
	***Other causes of [[bacterial meningitis]] after antibiotics		***Other causes of [[bacterial meningitis]] after antibiotics
	**Mycobacterial		**Mycobacterial

Aidan at 14:08, 17 September 2020

2020-09-17T14:08:29Z

← Older revision		Revision as of 14:08, 17 September 2020
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	* Signs and symptoms of meningeal inflammation with negative routine bacterial culture of CSF		*Signs and symptoms of meningeal inflammation with negative routine bacterial culture of CSF

	==Differential Diagnosis==		==Differential Diagnosis==
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	***[[Enterovirus]] EV-B species (includes Group B coxsackieviruses and echoviruses) are the most common cause of aseptic meningitis in both children and adults		***[[Enterovirus]] EV-B species (includes Group B coxsackieviruses and echoviruses) are the most common cause of aseptic meningitis in both children and adults
	****CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33		****CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33
			***[[Parechovirus]], especially in very young children and immunocompromised hosts
	***[[Herpes]] (especially HSV-2, as primary infection)		***[[Herpes]] (especially HSV-2, as primary infection)
	***[[Varicella]]		***[[Varicella]]

Aidan at 19:07, 14 September 2020

2020-09-14T19:07:16Z

← Older revision		Revision as of 19:07, 14 September 2020
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			* Signs and symptoms of meningeal inflammation with negative routine bacterial culture of CSF

	==Differential Diagnosis==		==Differential Diagnosis==

Aidan at 19:06, 14 September 2020

2020-09-14T19:06:45Z

← Older revision		Revision as of 19:06, 14 September 2020
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	***[[IVIg]]		***[[IVIg]]
	***[[Azathioprine]]		***[[Azathioprine]]
	***[[NSAIDs]]		***[[Ibuprofen]] and other [[NSAIDs]]
	***[[Allopurinol]]		***[[Allopurinol]]
	**Malignancy		**Malignancy
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	***[[Lymphoma]]		***[[Lymphoma]]
	***Metastatic [[carcinoma]] or [[adenocarcinoma]]		***Metastatic [[carcinoma]] or [[adenocarcinoma]]
			**Other
			***[[Epidermoid cyst]]
			***Post-vaccination

	==Investigations==		==Investigations==

Aidan at 19:06, 14 September 2020

2020-09-14T19:06:01Z

← Older revision		Revision as of 19:06, 14 September 2020
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	== Differential Diagnosis ==		==Differential Diagnosis==

	* Infectious		*Infectious
	** Viral		**Viral
	*** [[Enterovirus]] EV-B species (includes Group B coxsackieviruses and echoviruses) are the most common cause of aseptic meningitis in both children and adults		***[[Enterovirus]] EV-B species (includes Group B coxsackieviruses and echoviruses) are the most common cause of aseptic meningitis in both children and adults
	**** CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33		****CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33
	*** [[Herpes]] (especially HSV-2, as primary infection)		***[[Herpes]] (especially HSV-2, as primary infection)
	*** [[Varicella]]		***[[Varicella]]
	*** [[Mumps]] (encephalitis), measles (acute encephalitis)		***[[Mumps]] (encephalitis), measles (acute encephalitis)
	*** [[Arboviruses]]		***[[Arboviruses]]
	*** [[Lymphocytic choriomeningitis virus]] (LCMV)		***[[Lymphocytic choriomeningitis virus]] (LCMV)
	*** Acute [[HIV]]		***Acute [[HIV]]
	*** [[EBV]], [[influenza]], [[Colorado tick virus]], [[rabies]]		***[[EBV]], [[influenza]], [[Colorado tick virus]], [[rabies]]
	** Bacterial		**Bacterial
	*** [[Leptospirosis]]		***[[Leptospirosis]]
	*** [[Lyme disease]]		***[[Lyme disease]]
	*** [[Rickettsia species]] (before onset of fever)		***[[Rickettsia species]] (before onset of fever)
	*** Other causes of [[bacterial meningitis]] after antibiotics		***Other causes of [[bacterial meningitis]] after antibiotics
	** Mycobacterial		**Mycobacterial
	** Fungal		**Fungal
	* Non-infectious		*Non-infectious
			**Autoimmune or inflammatory
	** Systemic lupus erythematosus		***[[Systemic lupus erythematosus]]
⚫	** Drug-induced meningitis
			***[[Behçet disease]]
⚫	*** IVIg
			***[[Sarcoidosis]]
⚫	*** Azathioprine
			***[[Vogt-Koyanagi-Harada syndrome]]
⚫	*** NSAIDs
		⚫	**Drug-induced meningitis
	*** [[TMP-SMX]], [[amoxicillin]], [[isoniazid]]		***Antimicrobials: [[TMP-SMX]], [[amoxicillin]], [[isoniazid]]
⚫	*** Allopurinol
		⚫	***[[IVIg]]
		⚫	***[[Azathioprine]]
		⚫	***[[NSAIDs]]
		⚫	***[[Allopurinol]]
			**Malignancy
			***[[Leukemia]]
			***[[Lymphoma]]
			***Metastatic [[carcinoma]] or [[adenocarcinoma]]

	== Investigations ==		==Investigations==

	* Enterovirus		*[[Enterovirus]]
	** Usually positive PCR of CSF		**Usually positive PCR of CSF
	** Can look for enterovirus in stool, nasopharyngeal, and throat, as well as conjunctiva if there is conjunctivitis		**Can look for enterovirus in stool, nasopharyngeal, and throat, as well as conjunctiva if there is conjunctivitis
	** Persists in stool for several weeks, but less specific		**Persists in stool for several weeks, but less specific
	** NP preferred over throat		**NP preferred over throat
	* Parechovirus PCR if very young child or immunocompromised		*[[Parechovirus]] PCR if very young child or immunocompromised
	* West Nile IgM/IgG/PCR from CSF and blood		*[[West Nile virus]] IgM/IgG/PCR from CSF and blood
	* Syphilis screening EIA		*[[Syphilis]] screening EIA
	* HIV screen		*[[HIV]] screen

	[[Category:CNS infections]]		[[Category:CNS infections]]

Aidan: /* Differential Diagnosis */

2019-08-15T20:17:16Z

Differential Diagnosis

← Older revision		Revision as of 20:17, 15 August 2019
Line 3:		Line 3:
	* Infectious		* Infectious
	** Viral		** Viral
	*** EV-B species (includes Group B coxsackieviruses and echoviruses) are the most common cause of aseptic meningitis in both children and adults		*** [[Enterovirus]] EV-B species (includes Group B coxsackieviruses and echoviruses) are the most common cause of aseptic meningitis in both children and adults
	**** CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33		**** CV-B2 to CV-B5, E-6, E-6, E-9, E-11, E-13, E-16, E-18, E-30, and E-33
	*** Herpes (especially HSV-2, as primary infection)		*** [[Herpes]] (especially HSV-2, as primary infection)
	*** Varicella		*** [[Varicella]]
	*** Mumps (encephalitis), measles (acute encephalitis)		*** [[Mumps]] (encephalitis), measles (acute encephalitis)
	*** Arboviruses		*** [[Arboviruses]]
	*** Lymphocytic choriomeningitis virus (LCMV)		*** [[Lymphocytic choriomeningitis virus]] (LCMV)
	*** Acute HIV		*** Acute [[HIV]]
	*** EBV, influenza, Colorado tick virus, rabies		*** [[EBV]], [[influenza]], [[Colorado tick virus]], [[rabies]]
	** Bacterial		** Bacterial
	*** Leptospirosis		*** [[Leptospirosis]]
	*** Lyme disease		*** [[Lyme disease]]
	*** ~~Rickettsioses~~ (before onset of fever)		*** [[Rickettsia species]] (before onset of fever)
	*** Other causes of bacterial meningitis after antibiotics		*** Other causes of [[bacterial meningitis]] after antibiotics
	** Mycobacterial		** Mycobacterial
	** Fungal		** Fungal
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	*** Azathioprine		*** Azathioprine
	*** NSAIDs		*** NSAIDs
	*** ~~Septra~~, amoxicillin, isoniazid		*** [[TMP-SMX]], [[amoxicillin]], [[isoniazid]]
	*** Allopurinol		*** Allopurinol

Aidan at 20:15, 15 August 2019

2019-08-15T20:15:57Z

← Older revision		Revision as of 20:15, 15 August 2019
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	= Differential Diagnosis =		== Differential Diagnosis ==

	* Infectious		* Infectious
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	*** Allopurinol		*** Allopurinol

	= Investigations =		== Investigations ==

	* Enterovirus		* Enterovirus