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	<id>https://idwiki.org/index.php?action=history&amp;feed=atom&amp;title=Antiepileptic_drugs</id>
	<title>Antiepileptic drugs - Revision history</title>
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	<updated>2026-05-13T00:01:43Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://idwiki.org/index.php?title=Antiepileptic_drugs&amp;diff=7790&amp;oldid=prev</id>
		<title>Aidan at 15:11, 14 April 2021</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Antiepileptic_drugs&amp;diff=7790&amp;oldid=prev"/>
		<updated>2021-04-14T15:11:56Z</updated>

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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:11, 14 April 2021&lt;/td&gt;
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  &lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* Titrate over several months&lt;/div&gt;&lt;/td&gt;
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		<author><name>Aidan</name></author>
	</entry>
	<entry>
		<id>https://idwiki.org/index.php?title=Antiepileptic_drugs&amp;diff=4090&amp;oldid=prev</id>
		<title>Maintenance script: Imported from text file</title>
		<link rel="alternate" type="text/html" href="https://idwiki.org/index.php?title=Antiepileptic_drugs&amp;diff=4090&amp;oldid=prev"/>
		<updated>2020-07-04T01:17:23Z</updated>

		<summary type="html">&lt;p&gt;Imported from text file&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== General Approach ==&lt;br /&gt;
&lt;br /&gt;
* Partial seizure&lt;br /&gt;
** Phenytoin&lt;br /&gt;
** Carbamazepine (Tegretol)&lt;br /&gt;
** Lacosimide, especially as add-on&lt;br /&gt;
* Generalized&lt;br /&gt;
** &amp;#039;&amp;#039;&amp;#039;Valproic acid&amp;#039;&amp;#039;&amp;#039;, unless young woman&lt;br /&gt;
** Lamotrigine (Lamictal)&lt;br /&gt;
** Leviteracetam (Keppra)&lt;br /&gt;
** Phenobarbital&lt;br /&gt;
&lt;br /&gt;
== Considerations ==&lt;br /&gt;
&lt;br /&gt;
* Cost&lt;br /&gt;
** Phenytoin&lt;br /&gt;
** Valproic acid&lt;br /&gt;
** Carbamazepine&lt;br /&gt;
* Rapidity of onset&lt;br /&gt;
** Levitiracetam&lt;br /&gt;
** Clobazam&lt;br /&gt;
** Phenytoin&lt;br /&gt;
** Valproic acid&lt;br /&gt;
* Pregnancy&lt;br /&gt;
** Avoid valproic acid, phenytoin, topiramate, polypharmacy&lt;br /&gt;
** Lamotrigine, leviteracetam are good?&lt;br /&gt;
* Type of seizure&lt;br /&gt;
** Generalized&lt;br /&gt;
*** Valproic acid for boys&lt;br /&gt;
*** Lamotrigine for girls and women&lt;br /&gt;
** Focal&lt;br /&gt;
*** Carbamazepine&lt;br /&gt;
* Enzyme induction by concurrent medications&lt;br /&gt;
* Renal or hepatic metabolism and excretion&lt;br /&gt;
* Side effect profile&lt;br /&gt;
** Phenytoin&lt;br /&gt;
*** Hirsutism&lt;br /&gt;
*** Loading: hypotension, cardiac arrhythmias, and purple glove syndrome&lt;br /&gt;
** Valproic acid&lt;br /&gt;
*** PCOS&lt;br /&gt;
*** Fatty liver&lt;br /&gt;
** Skin reactions, especially with older medication&lt;br /&gt;
&lt;br /&gt;
== Initiation ==&lt;br /&gt;
&lt;br /&gt;
* Loading&lt;br /&gt;
** No need for loading unless in status epilepticus or high risk for recurrence&lt;br /&gt;
** IV loading of phenytoin can cause ataxia&lt;br /&gt;
** Other options can use IV valproic acid or levitiracetam, can use midazolam or propanol in the interim&lt;br /&gt;
* Titrate over several months&lt;br /&gt;
&lt;br /&gt;
[[Category:Medication]]&lt;/div&gt;</summary>
		<author><name>Maintenance script</name></author>
	</entry>
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