Antibiotic spectrum index - Revision history

Aidan: fixed typo

2025-10-10T14:16:24Z

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	\|[[Moxifloxacin]]		\|[[Moxifloxacin]]
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	\|[[Imipenem-cilastatin]]		\|[[Imipenem-cilastatin]]
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	\|[[Tigecycline]]		\|[[Tigecycline]]
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	MSSA = methicillin-susceptible [[Staphylococcus aureus]]; E/K = [[Escherichia coli]]/[[Klebsiella]]; M/H.flu = [[Moraxella]] and [[Haemophilus influenzae]]; Pseudo = [[Pseudomonas aeruginosa]]; MRSA = [[methicillin-resistant Staphylococcus aureus]]; PRP = penicillin-resistant [[pneumococcus]]; VRE = vancomycin-resistant [[Enterococcus]]; atypicals = [[Mycoplasma pneumoniae]] and [[Chlamidophila]]; MDRO = multidrug-resistant organisms		MSSA = methicillin-susceptible [[Staphylococcus aureus]]; E/K = [[Escherichia coli]]/[[Klebsiella]]; M/H.flu = [[Moraxella]] and [[Haemophilus influenzae]]; Pseudo = [[Pseudomonas aeruginosa]]; MRSA = [[methicillin-resistant Staphylococcus aureus]]; PRP = penicillin-resistant [[pneumococcus]]; VRE = vancomycin-resistant [[Enterococcus]]; atypicals = [[Mycoplasma pneumoniae]] and [[Chlamidophila]]; MDRO = multidrug-resistant organisms

Aidan: formatting, colour

2025-10-10T14:15:31Z

formatting, colour

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Aidan at 18:34, 4 April 2024

2024-04-04T18:34:06Z

← Older revision		Revision as of 18:34, 4 April 2024
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	* For each patient, the number of points for every antibiotic is added to give a total daily ASI		* For each patient, the number of points for every antibiotic is added to give a total daily ASI

	== ~~Sample~~ ~~Spectrum Indices~~ ==		== Working Ranking ==

			* The following is a reasonable list of commonly-used antibiotics, order from broadest to narrowest, not based on the ASI
			* [[Cefiderocol]], [[Colistin]], [[Polymyxin B]], [[Meropenem-vaborbactam]], [[Imipenem-relebactam]], [[Ceftazidime-avibactam]], [[Ceftolozane-tazobactam]], [[Tigecycline]], [[Meropenem]], [[Doripenem]], [[Ertapenem]], [[Piperacillin-tazobactam]], [[Ticarcillin-clavulanate]], [[Fosfomycin]], [[Moxifloxacin]], [[Levofloxacin]], [[Ciprofloxacin]], [[Doxycycline]], [[Amikacin]], [[Tobramycin]], [[Gentamicin]], [[Cefipime]], [[Ceftazidime]], [[Trimethoprim-sulfamethoxazole]], [[Ampicillin-sulbactam]], [[Amoxicillin-clavulanate]], [[Ceftaroline]], [[Ceftriaxone]], [[Cefuroxime]], [[Cefazolin]], [[Ampicillin]], [[Amoxicillin]]

			== Sample Spectrum Index ==
	{\| class="wikitable sortable"		{\| class="wikitable sortable"
	!Antibiotic		!Antibiotic

Aidan: added table caption

2022-09-22T12:20:30Z

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← Older revision		Revision as of 12:20, 22 September 2022
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	** Penicillin-resistant [[pneumococcus]] (PRP)		** Penicillin-resistant [[pneumococcus]] (PRP)
	** [[Moraxella]] and [[Haemophilus influenzae]]		** [[Moraxella]] and [[Haemophilus influenzae]]
	** [[Mycoplasma]] and [[Chlamydophila]]		** [[Mycoplasma]] and [[Chlamydophila]] (atypicals)
	** [[Anaerobes]] (in general)		** [[Anaerobes]] (in general)
	** [[Bacteriodes fragilis]] (specifically)		** [[Bacteriodes fragilis]] (specifically)
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	!Antibiotic		!Antibiotic
	!MSSA		!MSSA
			!E.faeca
	!Enterococcus
	!Anaerobes		!Anaerobes
	!Bacteroides		!Bacteroides
			!M/H.flu
	!Moraxella/Haemophilus
			!E/K
	!Escherichia/Klebsiella
	!AmpC		!AmpC
	!ESBL		!ESBL
			!Pseudo
	!Pseudomonas
	!MRSA		!MRSA
			!PRP
	!Pen-R pneumococcus
	!VRE		!VRE
			!Atypicals
	!Atypical
	!MDRO		!MDRO
	!ASI		!ASI
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	\|}		\|}
			MSSA = methicillin-susceptible [[Staphylococcus aureus]]; E/K = [[Escherichia coli]]/[[Klebsiella]]; M/H.flu = [[Moraxella]] and [[Haemophilus influenzae]]; Pseudo = [[Pseudomonas aeruginosa]]; MRSA = [[methicillin-resistant Staphylococcus aureus]]; PRP = penicillin-resistant [[pneumococcus]]; VRE = vancomycin-resistant [[Enterococcus]]; atypicals = [[Mycoplasma pneumoniae]] and [[Chlamidophila]]; MDRO = multidrug-resistant organisms

	==Further Reading==		==Further Reading==

Aidan: links

2022-09-22T12:16:20Z

links

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Aidan: added spectrum table

2022-09-22T12:13:32Z

added spectrum table

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Aidan: added links

2022-09-22T11:48:59Z

added links

← Older revision		Revision as of 11:48, 22 September 2022
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	* Measures the spectrum of an antibiotic, with a range from 0 to 14		* Measures the spectrum of an antibiotic, with a range from 0 to 14
	* One point for activity against each of the following:		* One point for activity against each of the following:
	** Methicillin-sensitive Staphylococcus aureus (MSSA)		** Methicillin-sensitive [[Staphylococcus aureus]] (MSSA)
	** Methicillin-resistant S. aureus (MRSA)		** [[Methicillin-resistant Staphylococcus aureus]] (MRSA)
	** Enterococcus faecalis		** [[Enterococcus faecalis]]
	** Vancomycin-resistant Enterococcus faecalis (VRE)		** Vancomycin-resistant [[Enterococcus faecalis]] (VRE)
	** Escherichia coli and Klebsiella		** [[Escherichia coli]] and [[Klebsiella]]
	** ~~ampC~~ producers		** [[AmpC β-lactamase\|AmpC producers]]
	** Extended-spectrum β-lactamase (ESBL) E. coli/Klebsiella		** [[Extended-spectrum β-lactamases\|Extended-spectrum β-lactamase]] (ESBL) E. coli/Klebsiella
	** Pseudomonas aeruginosa		** [[Pseudomonas aeruginosa]]
	** Penicillin-resistant pneumococcus (PRP)		** Penicillin-resistant [[pneumococcus]] (PRP)
	** Moraxella and Haemophilus influenzae		** [[Moraxella]] and [[Haemophilus influenzae]]
	** Mycoplasma and Chlamydophila		** [[Mycoplasma]] and [[Chlamydophila]]
	** Anaerobes (1 point; 2 points for Bacteriodes fragilis)		** [[Anaerobes]] (1 point; 2 points for [[Bacteriodes fragilis]])

	==Further Reading==		==Further Reading==

Aidan: Created page with "* Measures the spectrum of an antibiotic, with a range from 0 to 14 * One point for activity against each of the following: Methicillin-sensitive Staphylococcus aureus (MSSA) Methicillin-resistant S. aureus (MRSA) Enterococcus faecalis Vancomycin-resistant Enterococcus faecalis (VRE) Escherichia coli and Klebsiella ampC producers Extended-spectrum β-lactamase (ESBL) E. coli/Klebsiella Pseudomonas aeruginosa ** Penicillin-resistant pneumococcus (P..."

2022-09-22T11:46:35Z

Created page with "* Measures the spectrum of an antibiotic, with a range from 0 to 14 * One point for activity against each of the following: ** Methicillin-sensitive Staphylococcus aureus (MSSA) ** Methicillin-resistant S. aureus (MRSA) ** Enterococcus faecalis ** Vancomycin-resistant Enterococcus faecalis (VRE) ** Escherichia coli and Klebsiella ** ampC producers ** Extended-spectrum β-lactamase (ESBL) E. coli/Klebsiella ** Pseudomonas aeruginosa ** Penicillin-resistant pneumococcus (P..."

New page

* Measures the spectrum of an antibiotic, with a range from 0 to 14
* One point for activity against each of the following:
** Methicillin-sensitive Staphylococcus aureus (MSSA)
** Methicillin-resistant S. aureus (MRSA)
** Enterococcus faecalis
** Vancomycin-resistant Enterococcus faecalis (VRE)
** Escherichia coli and Klebsiella
** ampC producers
** Extended-spectrum β-lactamase (ESBL) E. coli/Klebsiella
** Pseudomonas aeruginosa
** Penicillin-resistant pneumococcus (PRP)
** Moraxella and Haemophilus influenzae
** Mycoplasma and Chlamydophila
** Anaerobes (1 point; 2 points for Bacteriodes fragilis)

==Further Reading==
* Development and Application of an Antibiotic Spectrum Index for Benchmarking Antibiotic Selection Patterns Across Hospitals. ''Infect Control Hosp Epidemiol''. 2017;38(8):993-997. doi: [https://doi.org/10.1017/ice.2017.94 10.1017/ice.2017.94].