Aidan: Created page with "* Monoclonal IgG1 antibody against CD52 Induces lysis of lymphoctes and other CD52 cells Results in severe and prolonged lymphopenia * Indications include B-cell c..."

2022-03-17T01:11:47Z

Created page with "* Monoclonal IgG1 antibody against CD52 ** Induces lysis of lymphoctes and other CD52 cells ** Results in severe and prolonged lymphopenia * Indications include B-cell c..."

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* Monoclonal IgG1 antibody against CD52
** Induces lysis of lymphoctes and other CD52 cells
** Results in severe and prolonged [[lymphopenia]]
* Indications include [[B-cell chronic lymphocytic leukemia]], [[T-cell prolymphocytic leukemia]], and [[non-Hodgkin lymphoma]]
* Infectious complications including severe [[bacteremia]], [[pneumonia]], [[meningitis]], [[CMV]], [[VZV]], [[HSV]], [[PJP]], [[PML]], [[acanthamebiasis]], [[Balamuthia mandrillaris]], [[toxoplasmosis]], [[histoplasmosis]], [[cryptococcosis]], [[aspergillosis]], other invasive fungal infections, [[BK virus]], [[HHV-6]], [[parvovirus]], [[adenovirus]], [[candidiasis]], [[TB]], [[NTM]], [[BCG]], and [[Rhodococcus]]
* Needs prophylaxis against [[PJP]] and [[herpesviruses]] for at least 2 months and until CD4 counts are ≥200

[[Category:Monoclonal antibodies]]

Alemtuzumab - Revision history

Aidan: Created page with "* Monoclonal IgG1 antibody against CD52 ** Induces lysis of lymphoctes and other CD52 cells ** Results in severe and prolonged lymphopenia * Indications include B-cell c..."

Aidan: Created page with "* Monoclonal IgG1 antibody against CD52 Induces lysis of lymphoctes and other CD52 cells Results in severe and prolonged lymphopenia * Indications include B-cell c..."