View source for Severe inflammatory response syndrome

== Definition ==

* SIRS requires two or more of the following:
** Temperature &gt;38 or &lt;36
** Heart rate &gt;90
** Respiratory rate &gt;20 or PaCO2 &lt;32
** WBC &gt;12k or &lt;4k, or bands &gt;10%
* Sepsis is SIRS with a suspected infection
* Severe sepsis is sepsis with end-organ dysfunction
** Elevated lactate
** Decreased urine output
** Elevated creatinine
** Elevated INR
* Septic shock is sepsis with shock despite adequate resuscitation

[[Category:Critical care]]
[[Category:Clinical exam]]