View source for Post-transplant acute limbic encephalitis

* Limbic encephalitis syndrome following hematopoietic stem cell transplantation

== Background ==
* Caused by [[HHV-6B]][[CiteRef::ongrádi2016ro]]

== Clinical Manifestations ==
* Onset 2 weeks to 2 months after transplant
* Presents with confusion, amnesia, hallucinations
* Can cause seizures
* Hyponatremia is common

== Management ==
* Treat seizures with antiepileptic medications
* Treat any possible concomitant risk factors such as hyponytremia
* Antivirals: [[Is treated by::acyclovir]], [[Is treated by::ganciclovir]], or [[Is treated by::foscarnet]] for 10 days to 4 weeks

== Further Reading ==
* Post-transplant acute limbic encephalitis: clinical features and relationship to HHV6. ''Neurology''. 2007;69(2):156-165. DOI: [https://doi.org/10.1212/01.wnl.0000265591.10200.d7 10.1212/01.wnl.0000265591.10200.d7]

[[Category:Immunocompromised hosts]]
[[Category:CNS infections]]