View source for Cryopyrin-associated periodic syndrome

== Background ==

* Mutation in NLRP3 gene
* One of the [[periodic fever syndrome]]

== Clinical Manifestations ==

* Three different clinical manifestations:
** [[Familial cold-associated syndrome]] (FCAS)
*** Episodes of fever, rashes, arthralgias, usually triggered by exposure to cold
** [[Muckle-Wells syndrome]] (MWS)
*** Episodes of fever, but with migrating urticaria-like lesions, ocular abnormalities, and progressive sensorineural deafness, and possibly amyloidosis
** [[Chronic infantile neurological cutaneous articular syndrome]] (CINCA syndrome)

[[Category:Periodic fever syndromes]]