View source for Corynebacterium jeikeium

* Species of [[Corynebacterium|''Corynebacterium'']] that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
* Essentially universally susceptible to [[vancomycin]] and [[linezolid]]
* High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible<ref name=":0">Neemuchwala A, Soares D, Ravirajan V, Marchand-Austin A, Kus JV, Patel SN. ''In Vitro'' Antibiotic Susceptibility Pattern of Non-diphtheriae Corynebacterium Isolates in Ontario, Canada, from 2011 to 2016. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01776-17. doi: [https://doi.org/10.1128/aac.01776-17 10.1128/AAC.01776-17]. PMID: [https://pubmed.ncbi.nlm.nih.gov/29339389/ 29339389]; PMCID: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5914010/ PMC5914010].</ref>
{| class="wikitable sortable"
|+From <ref name=":0" />
!Antibiotic
!Isolates
!% Susceptible
|-
|[[Penicillin]]
|76
|0
|-
|[[Ampicillin]]
|76
|ND
|-
|[[Oxacillin]]
|76
|ND
|-
|[[Erythromycin]]
|76
|11.8
|-
|[[Clindamycin]]
|76
|2.6
|-
|[[Ciprofloxacin]]
|75
|35.5
|-
|[[Levofloxacin]]
|75
|ND
|-
|[[Moxifloxacin]]
|76
|35.5
|-
|'''[[Tetracycline]]'''
|'''76'''
|'''92.1'''
|-
|'''[[Vancomycin]]'''
|'''76'''
|'''100'''
|-
|[[Trimethoprim-sulfamethoxazole]]
|76
|18.4
|-
|[[Tigecycline]]
|76
|ND
|-
|'''[[Rifampin]]'''
|'''76'''
|'''97.4'''
|-
|'''[[Quinupristin-dalfopristin]]'''
|'''76'''
|'''89.5'''
|-
|'''[[Linezolid]]'''
|'''76'''
|'''100'''
|-
|'''[[Gentamicin]]'''
|'''76'''
|'''81.6'''
|-
|'''[[Daptomycin]]'''
|'''75'''
|'''89.5'''
|-
|[[Chloramphenicol]]
|75
|ND
|-
|[[Nitrofurantoin]]
|76
|ND
|}
{| class="wikitable"
|
|
|
|
|
|
|-
|Penicillin
|76
|0.5 to >8
|>8
|>8
|0
|-
|    Ampicillin
|76
|≤0.12 to >8
|>8
|>8
|ND
|-
|    Oxacillin
|76
|0.5 to >4
|>4
|>4
|ND
|-
|    Erythromycin
|76
|≤0.25 to >4
|>4
|>4
|11.8
|-
|    Clindamycin
|76
|≤0.5 to >2
|>2
|>2
|2.6
|-
|    Ciprofloxacin
|75
|≤1 to >2
|>2
|>2
|35.5
|-
|    Levofloxacin
|75
|≤0.25 to >4
|>4
|>4
|ND
|-
|    Moxifloxacin<sup>''b''</sup>
|76
|≤0.25 to >4
|4
|>4
|35.5
|-
|    Tetracycline
|76
|≤2 to >16
|≤2
|≤2
|92.1
|-
|    Vancomycin
|76
|≤0.25 to 2
|0.50
|1
|100
|-
|    Trimethoprim-sulfamethoxazole
|76
|≤0.5 to >4
|>4
|>4
|18.4
|-
|    Tigecycline
|76
|≤0.03 to >0.5
|0.12
|0.25
|ND
|-
|    Rifampin
|76
|≤0.5 to >4
|≤0.5
|≤0.5
|97.4
|-
|    Quinupristin-dalfopristin
|76
|≤0.5 to 4
|≤0.5
|2
|89.5
|-
|    Linezolid
|76
|≤1
|≤1
|≤1
|100
|-
|    Gentamicin
|76
|≤2 to >16
|≤2
|>16
|81.6
|-
|    Daptomycin
|75
|≤0.5 to >4
|≤0.5
|1
|89.5
|-
|    Chloramphenicol
|75
|≤2 to >16
|4
|16
|ND
|-
|    Nitrofurantoin
|76
|≤32 to >64
|>64
|>64
|ND
|}
{{DISPLAYTITLE:''Corynebacterium jeikeium''}}
[[Category:Gram-positive bacilli]]