Thomasclavelia ramosa

Background

• Previously known as Clostridium ramosum
• Gram-positive, spore-forming, anaerobic bacillus
• Member of gastrointestinal flora
• Rarely causes disease in humans, usually in immunocompromised patients

Clinical Manifestations

• Can cause bacteremia, sometimes in mixed culture
  • Sources are usually GI-related or pressure sores

Further Reading

• A few case series of bacteremia:
  • Clostridium ramosum (C. ramosum) Bacteremia: Single-center Study. Open Forum Infect Dis. 2017;4(Suppl_1):S556. doi: 10.1093/ofid/ofx163.1446
  • Clostridium ramosum bacteremia: A case series at a general acute care hospital. J Infect Chemother. 2023 Jan;29(1):78-81. doi: 10.1016/j.jiac.2022.09.009. Epub 2022 Sep 23. PMID: 36154869.