Stable ischemic heart disease

From IDWiki

Management

Risk Factor Modification

  • Dyslipidemia
    • If CV risk >20%, high-intensity statin regardless of baseline lipids
    • If CV risk 7.5 to 20%, can use moderate-intensity statin
  • Hypertension
    • Following lifestyle modification, preference should be given to ACE inhibitors and ARBs
  • Diabetes mellitus
    • Good glycemic control
    • Likely benefits from SGLT-2 inhibitors
  • Diet & exercise
  • Cardiac rehab
  • Annual influenza vaccination

Coronary Artery Disease

  • Antiplatelet therapy: long-term ASA is recommended
  • Anticoagulation: can consider low-dose rivaroxaban 2.5 mg PO bid in addition to ASA if at high risk for CV disease and low bleeding risk
  • Lipid-lowering: see above
  • Beta-blockers
    • Used primarily as anti-anginal medication
      • Alternatives include calcium channel blockers and long-acting nitrates
      • Can use combination therapy if still symptomatic
    • Definitely indicated after ACS or heart failure, but unclear benefit in stable IHD
  • RAS inhibitors: indicated with acute MI, heart failure, LCEF <40%, diabetes, and proteinuric chronic kidney disease