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*A [[substance use disorder]] involving heroin, fentanyl, or other opioid medications ===Opioid Substitution Therapy (OST)===

*Recommended as first-line treatment for [[opioid use disorder]] in Canadian guidelines *Buprenorphine is partial μ-opioid receptor agonist

* Full opioid agonist ...ratory illness, sedating medications, liver or renal failure, or uncertain opioid tolerance)

*Full opioid agonist *Approved for chronic pain, but used off-label for [[opioid use disorder]]