Background
Etiologies
CNS: stroke , intracranial hemorrhage , infection, trauma, and psychosis
Malignancy: ectopic ADH production by small cell carcinoma or, even more rarely, with other lung cancers, head-and-neck cancer, olfactory neuroblastoma, and extrapulmonary small cell carcinoma
Medications: chlorpropamide , carbamazepine , oxcarbazepine , high-dose cyclophosphamide , SSRIs
Others: vincristine , cinblastine , cinorelbine , cisplatin , thiothixene , thioridazine , haloperidol , amitriptyline , MAO inhibitors , melphalan , ifosfamide , methotrexate , opiates , NSAIDs , interferon alpha , interferon gamma , sodium valproate , bromocriptine , lorcainide , amiodarone , ciprofloxacin , high-dose imatinib , and ecstasy
Surgery, likely mediated by pain, but also specifically after transsphenoidal pituitary surgery
Lung disease: pneumonia , occasionally also with asthma , atelectasis , respiratory failure, and pneumothorax
Endocrinopathies: hypopituitarism and hypothyroidism
HIV
Hereditary SIADH
Idiopathy, more common in older patients though occasionally found later to be from occult malignancy
Differential Diagnosis