Primary aldosteronism

From IDWiki
(Redirected from Primary hyperaldosteronism)

Clinical Manifestations

  • Usually asymptomatic except for hypertension and hypokalemia
  • Can have muscle cramps
  • Family history
  • Resistant hypertension
  • Adrenal incidentaloma
  • Early onset hypertension
  • High normal sodium
  • Metabolic alkalosis

Differential Diagnosis

Diagnosis

  • Screening with plasma aldosterone/plasma renin ratio
    • Done preferably in morning sample
    • Taken in a sitting position after at least 15 minutes of rest
    • Avoid aldosterone antagonists, ARBs, β-blockers
  • Diagnosed with:
    • Oral salt load
    • Saline suppression
    • Captopril

Management