Platelet transfusion
From IDWiki
Indications
- In non-immune thrombocytopenia, it is reasonable to maintain platelets over 10
- For procedures with low risk of blood loss (e.g. appendectomy, cholecystectomy, vaginal delivery)
- Platelets less than 20: transfuse 1 dose
- Platelets 20 to 50: transfuse 1 dose if significant bleeding occurs
- For procedures with high risk of blood loss, transfuse 1 dose for platelets less than 50
- For neurosurgery, ophthalmologic procedures, or significant head trauma with high risk of intracranial hemorrhage, maintain platelets above 100 (may need multiple doses)
- For bleeding from platelet dysfunction (e.g. post-cardiopulmonary bypass, or congenital platelet defect), transfusion may be required regardless of platelet count
Contraindications
- Caution in prothrombotic thrombocytopenia syndromes like HIT, TTP, and catastrophic antiphospholipid syndrome
- Of limited utility in ITP
