Phage therapy

Background

• Bacteriophages can be used to treat extensively drug-resistant infections, mostly gram-negative bacilli or mycobacteria
• Phages need to be trained for the specific bacterium and may be used synergistically with antibiotics

Access

• Process is in development, in Canada
• A regulatory nightmare

Companies

• Canadian companies
  • Cytophage (Winnipeg)
  • Phagelux (China-based company with site in Montreal)
• See also the Phage Directory

Further Reading

• Biological foundations of successful bacteriophage therapy. EMBO Mol Med. 2022:e12435.