Osteomyelitis with orthopedic hardware

From IDWiki

Management

  • Antimicrobial selection as per the management of osteomyelitis
  • Following complete explantation, 4 to 6 weeks of IV antibiotics
  • With retained hardware, 6 weeks of IV followed by stepdown to oral therapy for another 3 to 6 months (or lifelong suppression)

Further Reading

  • Four versus six weeks of antibiotic therapy for osteoarticular infections after implant removal: a randomized trial. J Antimicrob Chemother. 2019(74)8:2394-2399. doi: 10.1093/jac/dkz202