Nivolumab

From IDWiki
  • Immune checkpoint inhibitor targeting PD-1
  • Indicated for melanoma, NSCLC, SCLC, RCC, Hodgkin lymphoma, head and neck squamous cell carcinoma, urothelial carcinoma, colorectal cancer, hepatocellular carcinoma, and esophageal squamous cell carcinoma
  • Not particularly immunosuppressive
  • May increase risk of routine bacterial infections (including C. difficile), fungal infections (aspergillosis, pneumocystis, candidemia), viral infections (VZV, CMV, EBV)