Neonatal HCV
From IDWiki
Background
Epidemiology
- About 5% risk of vertical transmission, though higher if coinfected with HIV
- About half are transmitted antepartum and half intrapartum
Clinical Manifestations
- Asymptomatic, usually for decades, before slowly progressive liver disease
Management
Perinatal Exposure
- Not urgent, as it is a chronic illness that may not manifest for decades
- Serology to be done at 12-18 months for diagnosis
- If significant anxiety, can send HCV-PCR at 3 to 6 months
- 25-30% will spontaneous clear it
- Still need serology at 12-18 months, and repeat PCR around 18 months
