Multiple endocrine neoplasia type 1

From IDWiki

Background

  • Also called Wermer syndrome

Clinical Manifestations

  • 3 P's: parathyroid, pancreas, and pituitary
  • Parathyroid
  • Pancreas:
    • Endocrine tumours of the pancreas, including gastrinomas (causing Zollinger-Ellison syndrome) and insulinomas (causing hypoglycemia)
    • Often metastatic by the time of diagnosis
  • Pituitary